Researchers have created an intelligent bacterial strain that can detect and monitor inflammation biomarkers in the gut. It responds by releasing an immunomodulator, allowing for diagnosis and therapy for intestinal inflammation.
Engineered microbes show potential for diagnosing and treating diseases. In this issue of Cell Host & Microbe, Zou et al. develop an intelligentbacterial strain that detects and monitors an inflammation biomarker in the gut and responds by releasing an immunomodulator, thereby combining diagnosis and ther-apy for intestinal inflammation.
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