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Phuong T. Huynh et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
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Daisuke Izumi et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
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Dong Tang et al.
TUMOR BIOLOGY (2016)
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CANCER RESEARCH (2016)
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Christopher J. Tape et al.
CELL (2016)
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Sanya-Eduarda Kuzet et al.
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Michael R. Horsman et al.
JOURNAL OF RADIATION RESEARCH (2016)
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LANCET (2016)
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Yao Yuan et al.
ONCOLOGY REPORTS (2016)
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Katarzyna Ratajczak-Wielgomas et al.
ONCOLOGY REPORTS (2016)
Pericyte-fibroblast transition promotes tumor growth and metastasis
Kayoko Hosaka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion
Antonios Chronopoulos et al.
NATURE COMMUNICATIONS (2016)
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J-t Cheng et al.
ONCOGENESIS (2016)
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SCIENTIFIC REPORTS (2016)
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Mikkel Morsing et al.
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Carla Garza-Lombo et al.
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Raghu Kalluri
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Kingsley O. Osuala et al.
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Yasuhiko Ohshio et al.
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Chris D. Madsen et al.
EMBO REPORTS (2015)
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I. Acerbi et al.
INTEGRATIVE BIOLOGY (2015)
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Shinya Neri et al.
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Andrey Alexeyenko et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
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Go J. Yoshida
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Maria-Giuseppina Procopio et al.
NATURE CELL BIOLOGY (2015)
Differential regulation of the Hippo pathway by adherens junctions and apical-basal cell polarity modules
Chih-Chao Yang et al.
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Yuval Rinkevich et al.
SCIENCE (2015)
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Ryan R. Driskell et al.
TRENDS IN CELL BIOLOGY (2015)
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Fernando Vazquez-Villa et al.
TUMOR BIOLOGY (2015)
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Jean Albrengues et al.
NATURE COMMUNICATIONS (2015)
Cyclic stretching of soft substrates induces spreading and growth
Yidan Cui et al.
NATURE COMMUNICATIONS (2015)
Stretching Fibroblasts Remodels Fibronectin and Alters Cancer Cell Migration
Mingfang Ao et al.
SCIENTIFIC REPORTS (2015)
The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts
Anna Kuchnio et al.
CELL REPORTS (2015)
Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation
Daoxiang Zhang et al.
CELL REPORTS (2015)
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Lindsay T. McDonald et al.
NEOPLASIA (2015)
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Kazuyoshi Shiga et al.
CANCERS (2015)
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Najma Latif et al.
EUROPEAN HEART JOURNAL (2015)
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Rebeca San Martin et al.
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Francesca Gattazzo et al.
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Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
Y. Yu et al.
BRITISH JOURNAL OF CANCER (2014)
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Berna C. Oezdemir et al.
CANCER CELL (2014)
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Andrew D. Rhim et al.
CANCER CELL (2014)
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Mara H. Sherman et al.
CELL (2014)
CAF reprogramming inhibits ovarian cancer progression
Tsz-Lun Yeung et al.
CELL CYCLE (2014)
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Michael W. Pickup et al.
EMBO REPORTS (2014)
Fibroblast heterogeneity in the cancer wound
Daniel Oehlund et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
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George S. Karagiannis et al.
MOLECULAR ONCOLOGY (2014)
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L. J. A. C. Hawinkels et al.
ONCOGENE (2014)
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Kazuko Ino et al.
PLOS ONE (2014)
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Twana Alkasalias et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Carcinoma-associated fibroblasts provide operational flexibility in metastasis
Olivier De Wever et al.
SEMINARS IN CANCER BIOLOGY (2014)
TGF-beta in CAF-mediated tumor growth and metastasis
A. Calon et al.
SEMINARS IN CANCER BIOLOGY (2014)
Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling
Wan-Jiun Chen et al.
NATURE COMMUNICATIONS (2014)
Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity
Liang-Chuan S. Wang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Fibroblasts in fibrosis: novel roles and mediators
Ryan T. Kendall et al.
FRONTIERS IN PHARMACOLOGY (2014)
Docetaxel Conjugate Nanoparticles That Target α-Smooth Muscle Actin-Expressing Stromal Cells Suppress Breast Cancer Metastasis
Mami Murakami et al.
CANCER RESEARCH (2013)
Identification of Two Distinct Carcinoma-Associated Fibroblast Subtypes with Differential Tumor-Promoting Abilities in Oral Squamous Cell Carcinoma
Daniela Elena Costea et al.
CANCER RESEARCH (2013)
A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response
Ning Ding et al.
CELL (2013)
Carbonic anhydrase IX from cancer-associated ibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells
Tania Fiaschi et al.
CELL CYCLE (2013)
Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
Antonio Jimeno et al.
CLINICAL CANCER RESEARCH (2013)
Bone marrow cells as precursors of the tumor stroma
Daniel L. Worthley et al.
EXPERIMENTAL CELL RESEARCH (2013)
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
Michael A. Jacobetz et al.
GUT (2013)
Cancer cell bioenergetics and pH regulation influence breast cancer cell resistance to paclitaxel and doxorubicin
Diana Tavares-Valente et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2013)
Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force
Katarina Wolf et al.
JOURNAL OF CELL BIOLOGY (2013)
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
Edward W. Roberts et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
Eric Tran et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Antitumor Effects of Chimeric Receptor Engineered Human T Cells Directed to Tumor Stroma
Sunitha Kakarla et al.
MOLECULAR THERAPY (2013)
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Fernando Calvo et al.
NATURE CELL BIOLOGY (2013)
Microenvironmental regulation of tumor progression and metastasis
Daniela F. Quail et al.
NATURE MEDICINE (2013)
Candidate Markers That Associate with Chemotherapy Resistance in Breast Cancer through the Study on Taxotere-Induced Damage to Tumor Microenvironment and Gene Expression Profiling of Carcinoma-Associated Fibroblasts (CAFs)
Guohua Rong et al.
PLOS ONE (2013)
Tumor stroma as targets for cancer therapy
Jing Zhang et al.
PHARMACOLOGY & THERAPEUTICS (2013)
CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer
Albrecht Neesse et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury
Yuchang Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
Christine Feig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
'Cancer associated fibroblasts' - more than meets the eye
Shalom Madar et al.
TRENDS IN MOLECULAR MEDICINE (2013)
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
Vikash P. Chauhan et al.
NATURE COMMUNICATIONS (2013)
Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis
Younghun Jung et al.
NATURE COMMUNICATIONS (2013)
Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
Paolo Cirri et al.
CANCER AND METASTASIS REVIEWS (2012)
Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
Paolo P. Provenzano et al.
CANCER CELL (2012)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Exploiting Synthetic Lethality for the Therapy of ABC Diffuse Large B Cell Lymphoma
Yibin Yang et al.
CANCER CELL (2012)
Cancer Cells Cue the p53 Response of Cancer-Associated Fibroblasts to Cisplatin
Jens O. Schmid et al.
CANCER RESEARCH (2012)
Cancer-Associated Fibroblasts Drive the Progression of Metastasis through both Paracrine and Mechanical Pressure on Cancer Tissue
George S. Karagiannis et al.
MOLECULAR CANCER RESEARCH (2012)
Comprehensive care and care at the center of the new recommendation HAS
Elisa Derrien
ACTUALITES PHARMACEUTIQUES (2012)
Origins of the Tumor Microenvironment: Quantitative Assessment of Adipose-Derived and Bone Marrow-Derived Stroma
Shannon Kidd et al.
PLOS ONE (2012)
Functional Screen of Paracrine Signals in Breast Carcinoma Fibroblasts
Gui Su et al.
PLOS ONE (2012)
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
Triantafyllos Stylianopoulos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Desmoplasia in Pancreatic Cancer. Can We Fight It?
E. E. Merika et al.
GASTROENTEROLOGY RESEARCH AND PRACTICE (2012)
Interactions between cancer stem cells and their niche govern metastatic colonization
Ilaria Malanchi et al.
NATURE (2012)
ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma
Victoria Sanz-Moreno et al.
CANCER CELL (2011)
Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
Michael Quante et al.
CANCER CELL (2011)
Breast Cancer Subtype-Specific Interactions with the Microenvironment Dictate Mechanisms of Invasion
Tuyen T. Dang et al.
CANCER RESEARCH (2011)
Pancreatic Stellate Cells Radioprotect Pancreatic Cancer Cells through β1-Integrin Signaling
Tine S. Mantoni et al.
CANCER RESEARCH (2011)
Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis
Jacky G. Goetz et al.
CELL (2011)
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Greg M. Delgoffe et al.
CURRENT OPINION IN IMMUNOLOGY (2011)
Stromal biology and therapy in pancreatic cancer
Albrecht Neesse et al.
GUT (2011)
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Robert R. Langley et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Role of YAP/TAZ in mechanotransduction
Sirio Dupont et al.
NATURE (2011)
Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver
Christoph H. Oesterreicher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors
Benjamin Diop-Frimpong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization
Joyce T. O'Connell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Fibrocytes: emerging effector cells in chronic inflammation
Ronald A. Reilkoff et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Pathological roles of MAPK signaling pathways in human diseases
Eun Kyung Kim et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
Neta Erez et al.
CANCER CELL (2010)
Breast Carcinoma-Associated Fibroblasts Rarely Contain p53 Mutations or Chromosomal Aberrations
Abdel Nasser Hosein et al.
CANCER RESEARCH (2010)
Dishevelled: The hub of Wnt signaling
Chan Gao et al.
CELLULAR SIGNALLING (2010)
Overexpression of Smoothened Activates the Sonic Hedgehog Signaling Pathway in Pancreatic Cancer-Associated Fibroblasts
Kimberly Walter et al.
CLINICAL CANCER RESEARCH (2010)
Dynamic interplay between the collagen scaffold and tumor evolution
Mikala Egeblad et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Hallmarks of cancer: Interactions with the tumor stroma
Kristian Pietras et al.
EXPERIMENTAL CELL RESEARCH (2010)
Activation of fibroblasts in cancer stroma
Kati Rasanen et al.
EXPERIMENTAL CELL RESEARCH (2010)
Cancer associated fibroblasts (CAFs) in tumor microenvironment
Fei Xing et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2010)
The Fibroblast Integrin α11β1 Is Induced in a Mechanosensitive Manner Involving Activin A and Regulates Myofibroblast Differentiation
Sergio Carracedo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Louis Vermeulen et al.
NATURE CELL BIOLOGY (2010)
Methylation determines fibroblast activation and fibrogenesis in the kidney
Wibke Bechtel et al.
NATURE MEDICINE (2010)
The final steps of integrin activation: the end game
Sanford J. Shattil et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast
M. Bauer et al.
ONCOGENE (2010)
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-α
Matthew Kraman et al.
SCIENCE (2010)
Physico-mechanical aspects of extracellular matrix influences on tumorigenic behaviors
Edna Cukierman et al.
SEMINARS IN CANCER BIOLOGY (2010)
T Cells and Stromal Fibroblasts in Human Tumor Microenvironments Represent Potential Therapeutic Targets
Jennifer L. Barnas et al.
CANCER MICROENVIRONMENT (2010)
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CANCER CELL (2009)
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Purevdorj B. Olkhanud et al.
CANCER RESEARCH (2009)
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
Kandice R. Levental et al.
CELL (2009)
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Stephanos Pavlides et al.
CELL CYCLE (2009)
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Bryan T. MacDonald et al.
DEVELOPMENTAL CELL (2009)
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GENESIS (2009)
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Martin Mendoza et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer
Marcus C. B. Tan et al.
JOURNAL OF IMMUNOLOGY (2009)
Differential Influence of Normal and Cancer-Associated Fibroblasts on the Growth of Human Epithelial Cells in an In vitro Cocultivation Model of Prostate Cancer
Nicole Paland et al.
MOLECULAR CANCER RESEARCH (2009)
Pulmonary fibrosis: pathogenesis, etiology and regulation
M. S. Wilson et al.
MUCOSAL IMMUNOLOGY (2009)
Pten in stromal fibroblasts suppresses mammary epithelial tumours
Anthony J. Trimboli et al.
NATURE (2009)
Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive et al.
SCIENCE (2009)
The Nuclear Factor NF-κB Pathway in Inflammation
Toby Lawrence
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
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Kimberly Walter et al.
CANCER BIOLOGY & THERAPY (2008)
Shared principles in NF-κB signaling
Matthew S. Hayden et al.
CELL (2008)
Stromal fibroblasts activated by tumor cells promote angiogenesis in mouse gastric cancer
Xiaoying Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Periostin is expressed in pericryptal fibroblasts and cancer-associated fibroblasts in the colon
Yoshinao Kikuchi et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2008)
A paracrine requirement for hedgehog signalling in cancer
Robert L. Yauch et al.
NATURE (2008)
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
Wen Qiu et al.
NATURE GENETICS (2008)
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Matthias Schaefer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
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T. L. Whiteside
ONCOGENE (2008)
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Cedric Gaggioli et al.
NATURE CELL BIOLOGY (2007)
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Elisabeth M. Zeisberg et al.
CANCER RESEARCH (2007)
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Kalyani Narra et al.
CANCER BIOLOGY & THERAPY (2007)
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Tint Lwin et al.
BLOOD (2007)
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Elisabeth M. Zeisberg et al.
NATURE MEDICINE (2007)
Integrin all regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells
Chang-Qi Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
beta 1 integrin mediated adhesion increases Bim protein degradation and contributes to drug resistance in leukaemia cells
L. A. Hazlehurst et al.
BRITISH JOURNAL OF HAEMATOLOGY (2007)
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Robin J. McAnulty
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
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Paolo P. Provenzano et al.
BMC MEDICINE (2006)
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Hikaru Sugimoto et al.
CANCER BIOLOGY & THERAPY (2006)
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D. Ribatti et al.
CLINICAL AND EXPERIMENTAL MEDICINE (2006)
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Markus Loeffler et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
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Ami Citri et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Good cop, bad cop:: the different faces of NF-κB
ND Perkins et al.
CELL DEATH AND DIFFERENTIATION (2006)
Intestinal fibroblast-derived IL-10 increases survival of mucosal T cells by inhibiting growth factor deprivation- and fas-mediated apoptosis
K Ina et al.
JOURNAL OF IMMUNOLOGY (2005)
Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent proinvasive signals to human colon cancer cells through RhoA and Rac
O De Wever et al.
FASEB JOURNAL (2004)
The treatment of cancer in Greek antiquity
A Karpozilos et al.
EUROPEAN JOURNAL OF CANCER (2004)
Molecular characterization of the tumor microenvironment in breast cancer
M Allinen et al.
CANCER CELL (2004)
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K Fukino et al.
CANCER RESEARCH (2004)
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A Desmouliere et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2004)
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OW Petersen et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
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MA Huber et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2003)
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
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