Recent advances in the use of Steady-State Isotopic Transient Kinetic Analysis data in (micro)kinetic modeling for catalyst and process design

Developing new catalysts with improved performance is crucial for establishing a sustainable chemical industry and requires atomic-scale knowledge of the relevant catalyst-species interactions. A powerful experimental technique to gather such detailed knowledge is Steady-State Isotopic Transient Kinetic Analysis (SSITKA). By combining SSITKA with (micro)kinetic modeling, the observed catalyst performance can be rationalized to advance the development of structure-activity relationships, and to obtain fundamental insights in complex reaction pathways. In turn, tailored experimental and computational methodologies provide the tools to access this detailed information. This mini review summarizes the developments that have been made in these fields during the last decade.

Automated summary

Developing new catalysts with improved performance is crucial for a sustainable chemical industry. Steady-State Isotopic Transient Kinetic Analysis (SSITKA) is a powerful experimental technique that provides detailed knowledge of catalyst-species interactions. By combining SSITKA with (micro)kinetic modeling, structure-activity relationships can be advanced and insights into complex reaction pathways can be obtained. This mini review summarizes the developments in these fields over the last decade.