4.7 Article

PTPRO suppresses lymph node metastasis of esophageal carcinoma by dephosphorylating MET

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Immunology

PTPRO-related CD8+ T-cell signatures predict prognosis and immunotherapy response in patients with breast cancer

Hongmei Dong et al.

Summary: PTPRO significantly influences CD8(+) T-cell infiltration in breast cancer, suggesting a potential role in immunomodulation. The PTPRO-based PTS provides a new immune cell paradigm for prognosis, which is valuable for immunotherapy decisions in cancer patients.

FRONTIERS IN IMMUNOLOGY (2022)

Article Cell Biology

Neoantigen-based cancer vaccination using chimeric RNA-loaded dendritic cell-derived extracellular vesicles

Xiao Xiong et al.

Summary: This study demonstrates the potential of using cancer-specific transcription-induced chimeric RNAs to produce a cell-free cancer vaccine that induces potent CD8(+) T cell-mediated anticancer immunity. This novel approach may be particularly useful for developing cancer vaccines to treat malignancies with low mutational burden or without mutation-based antigens.

JOURNAL OF EXTRACELLULAR VESICLES (2022)

Article Cell Biology

Tumor-Derived Exosomal Protein Tyrosine Phosphatase Receptor Type O Polarizes Macrophage to Suppress Breast Tumor Cell Invasion and Migration

Hongmei Dong et al.

Summary: The study found that the tumor-derived exosomal PTPRO inhibits breast cancer invasion and migration by modulating macrophage polarization. The anti-tumoral effect of exosomal PTPRO is mediated by inactivating the STAT family in macrophages, highlighting a novel mechanism for therapeutic strategies against breast cancer.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Multidisciplinary Sciences

Splice variant of growth hormone-releasing hormone receptor drives esophageal squamous cell carcinoma conferring a therapeutic target

Xiao Xiong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Biochemistry & Molecular Biology

Systems Biology of Cancer Metastasis

Yasir Suhail et al.

CELL SYSTEMS (2019)

Article Obstetrics & Gynecology

Clinical significance of c-Met and phospho-c-Met (Tyr1234/1235) in ovarian cancer

Ling Lim et al.

TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY (2019)

Article Oncology

Intracranial Activity of Cabozantinib in MET Exon 14-Positive NSCLC with Brain Metastases

Samuel J. Klempner et al.

JOURNAL OF THORACIC ONCOLOGY (2017)

Article Medicine, Research & Experimental

Activation of MET pathway predicts poor outcome to cetuximab in patients with recurrent or metastatic head and neck cancer

Juan Madoz-Gurpide et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2015)

Review Oncology

Targeting MET Amplification as a New Oncogenic Driver

Hisato Kawakami et al.

CANCERS (2014)

Article Oncology

Gene amplification of EGFR, HER2, FGFR2 and MET in esophageal squamous cell carcinoma

Hiroaki Kato et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2013)

Article Biochemistry & Molecular Biology

Substrate Specificity of R3 Receptor-like Protein-tyrosine Phosphatase Subfamily toward Receptor Protein-tyrosine Kinases

Juichi Sakuraba et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Medicine, Research & Experimental

PTPRO promoter methylation is predictive of poorer outcome for HER2-positive breast cancer: indication for personalized therapy

Yi-Teng Huang et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2013)

Article Oncology

The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype

Francesca De Bacco et al.

CANCER RESEARCH (2012)

Review Oncology

Inside the human cancer tyrosine phosphatome

Sofi G. Julien et al.

NATURE REVIEWS CANCER (2011)

Review Cell Biology

MET signalling: principles and functions in development, organ regeneration and cancer

Livio Trusolino et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Regulation of the Met Receptor-tyrosine Kinase by the Protein-tyrosine Phosphatase 1B and T-cell Phosphatase

Veena Sangwan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

Jeffrey A. Engelman et al.

SCIENCE (2007)

Article Multidisciplinary Sciences

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

GA Smolen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Oncology

Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice

XH Tang et al.

CLINICAL CANCER RESEARCH (2004)

Review Cell Biology

Met, metastasis, motility and more

C Birchmeier et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)