Chemotherapy-Induced Oral Complications and Prophylaxis Strategies

Cancer is currently a significant therapeutic challenge and is frequently connected with numerous adverse effects. Despite many improvements in chemotherapy, oral complications are common, leading to poor quality of life and chemotherapeutic dose reduction, which impair survival. This review summarizes the most common dental complications in patients receiving chemotherapy. We mainly focus on oral mucositis as it is a major cause of dose-limiting toxicity. Furthermore, oral candidiasis, viral infections, and xerostomia will be discussed. Conclusions: preventing complications is significantly more important than treating them. All patients beginning systemic anticancer treatment should undergo a thorough oral examination and get appropriate prophylaxis.

Automated summary

Cancer treatment poses a significant challenge, often resulting in adverse effects, including oral complications. This review focuses on the common dental problems encountered by patients undergoing chemotherapy, with a particular emphasis on oral mucositis, a major dose-limiting toxicity. Additionally, oral candidiasis, viral infections, and xerostomia are discussed. The prevention of these complications is crucial, and all patients should undergo a thorough oral examination and receive appropriate prophylaxis before starting systemic anticancer treatment.