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GM1 promotes TrkA-mediated neuroblastoma cell differentiation by occupying a plasma membrane domain different from TrkA
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Glycosylation in health and disease
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Ganglioside GD1a suppresses LPS-induced pro-inflammatory cytokines in RAW264.7 macrophages by reducing MAPKs and NF-κB signaling pathways through TLR4
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NATURE CHEMICAL BIOLOGY (2015)
Gangliosides Drive the Tumor Infiltration and Function of Myeloid-Derived Suppressor Cells
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Monosialic ganglioside GM3 specifically suppresses the monocyte adhesion to endothelial cells for inflammation
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The Ganglioside GM3 Is Associated with Cisplatin-Induced Apoptosis in Human Colon Cancer Cells
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Detection of N-glycolyated gangliosides in non-small-cell lung cancer using GMR8 monoclonal antibody
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Ganglioside GM3 inhibits hepatoma cell motility via down-regulating activity of EGFR and PI3K/AKT signaling pathway
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Ganglioside GM3 promotes HGF-stimulated motility of murine hepatoma cell through enhanced phosphorylation of cMet at specific tyrosine sites and PI3K/Akt-mediated migration signaling
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Altered ganglioside GD3 in HeLa cells might influence the cytotoxic abilities of NK cells
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Relationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer
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Ganglioside-exposed dendritic cells inhibit T-cell effector function by promoting regulatory cell activity
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GM1/GD1b/GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line
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CANCER RESEARCH (2009)
Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells
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Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer
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Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells
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In vivo modulation of epidermal growth factor receptor phosphorylation in mice expressing different Gangliosides
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Milk-derived GM3 and GD3 differentially inhibit dendritic cell maturation and effector functionalities
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Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis
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Gangliosides inhibit the development from monocytes to dendritic cells
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Inhibition of human neuroblastoma cell proliferation and EGF receptor phosphorylation by gangliosides GM1, GM3 GD1A and GT1B
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Ganglioside GD1a enhances immunoglobulin production by human peripheral blood mononuclear cells
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EXPERIMENTAL HEMATOLOGY (2000)
Inverse relationship of expression between GM3 and globo-series ganglioside in human renal cell carcinoma
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