相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。KEGG for taxonomy-based analysis of pathways and genomes
Minoru Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2023)
Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H
Kevin P. Kotredes et al.
FRONTIERS IN AGING NEUROSCIENCE (2021)
TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF-κB signaling
Caixia Li et al.
CELL BIOLOGY INTERNATIONAL (2019)
IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences
Kristoffer Vitting-Seerup et al.
BIOINFORMATICS (2019)
Microglia-neuron crosstalk: Signaling mechanism and control of synaptic transmission
Silvia Marinelli et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2019)
Alteration of scaffold: Possible role of MACF1 in Alzheimer's disease pathogenesis
Xiaolong Wang et al.
MEDICAL HYPOTHESES (2019)
Toward understanding the origin and evolution of cellular organisms
Minoru Kanehisa
PROTEIN SCIENCE (2019)
RNA Splicing and Disease: Animal Models to Therapies
Matias Montes et al.
TRENDS IN GENETICS (2019)
RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease
Isaac Bishof et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease
Paul J. Cheng-Hathaway et al.
MOLECULAR NEURODEGENERATION (2018)
Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain
Guillermo Carbajosa et al.
NEUROBIOLOGY OF AGING (2018)
TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
Yingjun Zhao et al.
NEURON (2018)
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans
Xianyuan Xiang et al.
MOLECULAR NEURODEGENERATION (2018)
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility
Towfique Raj et al.
NATURE GENETICS (2018)
Bidirectional Microglia-Neuron Communication in Health and Disease
Zsuzsanna Szepesi et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease
Erik C. B. Johnson et al.
MOLECULAR NEURODEGENERATION (2018)
Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy
Heike J. Wobst et al.
SCIENTIFIC REPORTS (2017)
RNA mis-splicing in disease
Marina M. Scotti et al.
NATURE REVIEWS GENETICS (2016)
Loss of the tumor suppressor spinophilin (PPP1R9B) increases the cancer stem cell population in breast tumors
I. Ferrer et al.
ONCOGENE (2016)
Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisenseoligonucleotides
Anthony J. Hinrich et al.
EMBO MOLECULAR MEDICINE (2016)
The hnRNP family: insights into their role in health and disease
Thomas Geuens et al.
HUMAN GENETICS (2016)
TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
Felix L. Yeh et al.
NEURON (2016)
Altered protein phosphorylation as a resource for potential AD biomarkers
Ana Gabriela Henriques et al.
SCIENTIFIC REPORTS (2016)
Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations
Sarah Bianchi et al.
SCIENTIFIC REPORTS (2016)
HTSeq-a Python framework to work with high-throughput sequencing data
Simon Anders et al.
BIOINFORMATICS (2015)
Trimmomatic: a flexible trimmer for Illumina sequence data
Anthony M. Bolger et al.
BIOINFORMATICS (2014)
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
Ye Zhang et al.
JOURNAL OF NEUROSCIENCE (2014)
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Claudio Franceschi et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
RBPmap: a web server for mapping binding sites of RNA-binding proteins
Inbal Paz et al.
NUCLEIC ACIDS RESEARCH (2014)
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
Gernot Kleinberger et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Abundant kif21b is associated with accelerated progression in neurodegenerative diseases
Karim L. Kreft et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
A survey of software for genome-wide discovery of differential splicing in RNA-Seq data
Joan E. Hooper
HUMAN GENOMICS (2014)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing
Maria Elena Avale et al.
HUMAN MOLECULAR GENETICS (2013)
TREM2 R47H Variant as a Risk Factor for Early-Onset Alzheimer's Disease
Cyril Pottier et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Alternative splicing: a pivotal step between eukaryotic transcription and translation
Alberto R. Kornblihtt et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Thorlakur Jonsson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Genetic deletion could increase the risk of early-onset Parkinson's disease
[Anonymous]
FUTURE NEUROLOGY (2013)
RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer's brain synaptosomes
J. P. Palavicini et al.
CELL DEATH & DISEASE (2013)
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease
Bing Bai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Detecting differential usage of exons from RNA-seq data
Simon Anders et al.
GENOME RESEARCH (2012)
MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
Daniah Trabzuni et al.
HUMAN MOLECULAR GENETICS (2012)
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
Guangchuang Yu et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)
The Evolutionary Landscape of Alternative Splicing in Vertebrate Species
Nuno L. Barbosa-Morais et al.
SCIENCE (2012)
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li et al.
BMC BIOINFORMATICS (2011)
Alternative isoform regulation in human tissue transcriptomes
Eric T. Wang et al.
NATURE (2008)
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
Qun Pan et al.
NATURE GENETICS (2008)
Heterogeneous ribonucleoprotein M is a splicing regulatory protein that can enhance or silence splicing of alternatively spliced Exons
Ruben H. Hovhannisyan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Splicing in disease: disruption of the splicing code and the decoding machinery
Guey-Shin Wang et al.
NATURE REVIEWS GENETICS (2007)
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Tetsuaki Arai et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis
S Durinck et al.
BIOINFORMATICS (2005)
Heterozygous mutations of the kinesin KIF21A in congenital fibrosis of the extraocular muscles type 1 (CFEOM1)
K Yamada et al.
NATURE GENETICS (2003)
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
L Buée et al.
BRAIN RESEARCH REVIEWS (2000)
KEGG: Kyoto Encyclopedia of Genes and Genomes
M Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2000)
分享论文
