4.4 Article

Non-24-h sleep-wake rhythm disorder in a sighted individual with bipolar disorder

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Behaviorally and environmentally induced non-24-hour sleep-wake rhythm disorder in sighted patients

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Summary: This study found no evidence of circadian dysfunction in sighted individuals with non-24-hour sleep-wake rhythm disorder. Instead, sleep-wake timing appeared to dissociate from the circadian timing system, and the disorder may be light- and/or behaviorally induced.

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Summary: This study found that individuals with a late chronotype were more likely to experience depressive symptoms over a 5-year period, even after adjusting for age, sex, and baseline mood. Late chronotypes also reported fewer hypomania/mania episodes during the follow up. These results suggest that circadian phase advancing treatments should be explored as a means to reduce depressive symptoms in late chronotypes with bipolar disorder.

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Non-24-Hour Sleep - Wake Syndrome in Sighted and Blind Patients

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