Microneedle arrays integrated with microfluidic systems: Emerging applications and fluid flow modeling

Microneedle arrays are patches of needles at micro- and nano-scale, which are competent and versatile technologies that have been merged with microfluidic systems to construct more capable devices for biomedical applications, such as drug delivery, wound healing, biosensing, and sampling body fluids. In this paper, several designs and applications are reviewed. In addition, modeling approaches used in microneedle designs for fluid flow and mass transfer are discussed, and the challenges are highlighted.

Automated summary

This paper reviews the designs and applications of microneedle arrays, which are micro- and nano-scale patches of needles that have been combined with microfluidic systems to create more advanced devices for biomedical applications, including drug delivery, wound healing, biosensing, and body fluid sampling. The paper also discusses modeling approaches for fluid flow and mass transfer in microneedle designs and highlights the challenges.