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Florence Jornod et al.
BIOINFORMATICS (2022)
mTOR inhibitor PP242 increases antitumor activity of sulforaphane by blocking Akt/mTOR pathway in esophageal squamous cell carcinoma
Zhaoming Lu et al.
MOLECULAR BIOLOGY REPORTS (2022)
Tumor Promoting Effects of Sulforaphane on Diethylnitrosamine-Induced Murine Hepatocarcinogenesis
Jie Zheng et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Prediction of Oral Acute Toxicity of Organophosphates Using QSAR Methods
Mina Kianpour et al.
CURRENT COMPUTER-AIDED DRUG DESIGN (2021)
Comparative Toxicogenomics Database (CTD): update 2021
Allan Peter Davis et al.
NUCLEIC ACIDS RESEARCH (2021)
Sulforaphane enhances the antitumor response of chimeric antigen receptor T cells by regulating PD-1/PD-L1 pathway
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BMC MEDICINE (2021)
Sulforaphane Causes Cell Cycle Arrest and Apoptosis in Human Glioblastoma U87MG and U373MG Cell Lines under Hypoxic Conditions
Giulia Sita et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway
Marija Petkovic et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2021)
Potential of Sulforaphane as a Natural Immune System Enhancer: A Review
Andrea Mahn et al.
MOLECULES (2021)
Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation
Yanhong Shou et al.
CELL DEATH & DISEASE (2021)
Daily Lifestyle and Inflammatory Skin Diseases
Yu Sawada et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Deciphering Adverse Outcome Pathway Network Linked to Bisphenol F Using Text Mining and Systems Toxicology Approaches
Marylene Rugard et al.
TOXICOLOGICAL SCIENCES (2020)
Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells
Patrick Wellington da Silva dos Santos et al.
FOOD AND CHEMICAL TOXICOLOGY (2020)
Sulforaphane as an anticancer molecule: mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems
Mohammad M. Kamal et al.
ARCHIVES OF PHARMACAL RESEARCH (2020)
The Combination of Sulforaphane and Fernblock (R) XP Improves Individual Beneficial Effects in Normal and Neoplastic Human Skin Cell Lines
Simona Serini et al.
NUTRIENTS (2020)
The Integrative Role of Sulforaphane in Preventing Inflammation, Oxidative Stress and Fatigue: A Review of a Potential Protective Phytochemical
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ANTIOXIDANTS (2020)
Predicting the mutagenic potential of chemicals in tobacco products usingin silicotoxicology tools
Reema Goel et al.
TOXICOLOGY MECHANISMS AND METHODS (2020)
Salinomycin and Sulforaphane Exerted Synergistic Antiproliferative and Proapoptotic Effects on Colorectal Cancer Cells by Inhibiting the PI3K/Akt Signaling Pathway in vitro and in vivo
Fang Liu et al.
ONCOTARGETS AND THERAPY (2020)
The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Taoming Liu et al.
FRONTIERS IN IMMUNOLOGY (2020)
Linking Bisphenol S to Adverse Outcome Pathways Using a Combined Text Mining and Systems Biology Approach
Jean-Charles Carvaillo et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2019)
Broccoli or Sulforaphane: Is It the Source or Dose That Matters?
Yoko Yagishita et al.
MOLECULES (2019)
Sulforaphane: Its Coming of Age as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease
Christine A. Houghton
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Pathophysiology of atopic dermatitis: Clinical implications
Jihyun Kim et al.
ALLERGY AND ASTHMA PROCEEDINGS (2019)
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis
Chunfeng Xie et al.
THERANOSTICS (2019)
Antitumor activity and expression profiles of genes induced by sulforaphane in human melanoma cells
Paola Arcidiacono et al.
EUROPEAN JOURNAL OF NUTRITION (2018)
AOP-DB: A database resource for the exploration of Adverse Outcome Pathways through integrated association networks
Maureen E. Pittman et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2018)
Skin Gene Expression Is Prognostic for the Trajectory of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis
Giuseppina Stifano et al.
ARTHRITIS & RHEUMATOLOGY (2018)
Increased seizure susceptibility and other toxicity symptoms following acute sulforaphane treatment in mice
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TOXICOLOGY AND APPLIED PHARMACOLOGY (2017)
Classification of baseline toxicants for QSAR predictions to replace fish acute toxicity studies
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ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS (2017)
NaviGO: interactive tool for visualization and functional similarity and coherence analysis with gene ontology
Qing Wei et al.
BMC BIOINFORMATICS (2017)
The effect of sulforaphane on the cell cycle, apoptosis and expression of cyclin D1 and p21 in the A549 non-small cell lung cancer cell line
Agnieszka Zuryn et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Sulforaphene-Carboplatin Combination Synergistically Enhances Apoptosis by Disruption of Mitochondrial Membrane Potential and Cell Cycle Arrest in Human Non-Small Cell Lung Carcinoma
Saswata Chatterjee et al.
JOURNAL OF MEDICINAL FOOD (2016)
Hypoxia-Inducible Factors Regulate Filaggrin Expression and Epidermal Barrier Function
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JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)
NetworkAnalyst - integrative approaches for protein-protein interaction network analysis and visual exploration
Jianguo Xia et al.
NUCLEIC ACIDS RESEARCH (2014)
Sulforaphane and phenylethyl isothiocyanate protect human skin against UVR-induced oxidative stress and apoptosis: Role of Nrf2-dependent gene expression and antioxidant enzymes
Konrad Kleszczynski et al.
PHARMACOLOGICAL RESEARCH (2013)
PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress
So Young Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells
Yoon-Jin Lee et al.
FOOD AND CHEMICAL TOXICOLOGY (2012)
In Silico Quantitative Structure Toxicity Relationship of Chemical Compounds: Some Case Studies
Omar Deeb et al.
CURRENT DRUG SAFETY (2012)
Challenges for computational structure-activity modelling for predicting chemical toxicity: future improvements?
Robert D. Combes
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2011)
Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture
Anika E. Wagner et al.
EXPERIMENTAL DERMATOLOGY (2010)
Interaction of the isothiocyanate sulforaphane with drug disposition and metabolism: Pharmacological and toxicological implications
C. Fimognari et al.
CURRENT DRUG METABOLISM (2008)
Notch signaling: Its role in epidermal homeostasis and in the pathogenesis of skin diseases
Ryuhei Okuyama et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2008)
Modulation of cell-mediated immune response in B16F-10 melanoma-induced metastatic tumor-bearing C57BL/6 mice by sulforaphane
P. Thejass et al.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2007)
Apoptosis: A review of programmed cell death
Susan Elmore
TOXICOLOGIC PATHOLOGY (2007)
Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells
Young-Sam Keum et al.
CANCER RESEARCH (2006)
Keratinocyte apoptosis in epidermal development and disease
Deepak Raj et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)
Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells
G Parnaud et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2004)
Computer systems for the prediction of toxicity: an update
N Greene
ADVANCED DRUG DELIVERY REVIEWS (2002)
Contact dermatitis: clinics and pathology
M Streit et al.
ACTA ODONTOLOGICA SCANDINAVICA (2001)
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