4.5 Article

Flow cytometry as an analytical method of drug-induced apoptosis in 3D bioprinted melanoma cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Novel biological insights revealed from the investigation of multiscale genome architecture

Tianyi Ding et al.

Summary: Gene expression and cell fate determination rely on precise and coordinated epigenetic regulation, which is influenced by the complex three-dimensional (3D) organization of the genome. Various architectural features of the 3D genome, such as chromatin loops, topologically associated domains (TADs), and chromatin compartments, play significant roles in regulating chromatin state and transcriptional activity. Recent advances in 3D genome informatics, biochemistry, and imaging have allowed the exploration of functional interactions among biomacromolecules, including at the single-cell level. This review provides an overview of dynamic genome organization, discussing its occurrence, mechanistic basis, functional implications, and recent experimental and computational approaches used for studying the 3D genome.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2023)

Review Biochemistry & Molecular Biology

Modification, 3D printing process and application of sodium alginate based hydrogels in soft tissue engineering: A review

Qinghua Wei et al.

Summary: This article summarizes the application of sodium alginate (SA) in biological soft tissue repair/regeneration, especially its use in tissue engineering with the advent of 3D bioprinting technology. The article reviews SA modification methods and provides a comparative analysis of the characteristics of various SA-based hydrogels. It also introduces various molding methods of SA-based hydrogels, analyzes and compares the processing characteristics and applications of different molding methods. Additionally, it reviews the applications of SA-based hydrogels in tissue engineering, analyzes the challenges in their applications, and discusses future research directions.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

Review Biochemistry & Molecular Biology

Classification, processing, and applications of bioink and 3D bioprinting: A detailed review

Sania Raees et al.

Summary: With the advancement in 3D bioprinting technology, the design of complex and physiologically relevant 3D environments through cell culture methods has become possible. The choice of bioink and bioprinting process is crucial and depends on factors such as material properties, biological interaction, gelation, and viscosity. The foundation of 3D bioprinting lies in the precise layer-by-layer implantation of biological elements onto biofabricated 3D structures, with three basic strategies being used: autonomous self-assembly, micro tissue building blocks, and biomimicry. However, there are still obstacles to overcome before functional tissues can be effectively produced and used in clinical settings, requiring a better understanding of bioink materials and the ability to reproduce intricate 3D structures mimicking biology and physiology.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

Article Peripheral Vascular Disease

Oseltamivir phosphate loaded pegylated-Eudragit nanoparticles for lung cancer therapy: Characterization, prolonged release, cytotoxicity profile, apoptosis pathways and in vivo anti-angiogenic effect by using CAM assay

Gulsel Yurtdas-Kirimlioglu et al.

Summary: The study aimed to deliver oseltamivir phosphate (OSE) into lung adenocarcinoma tissues using innovative nanosized pegylated Eudragit based nanoparticles, showing promising anticancer and antiangiogenic activities. The OSE loaded PEG-ERS nanoparticles demonstrated excellent characteristics both in vitro and in vivo, indicating its potential as a potent drug delivery system for lung cancer treatment.

MICROVASCULAR RESEARCH (2022)

Article Biophysics

Three dimensional bioprinting technology: Applications in pharmaceutical and biomedical area

Esen Kocak et al.

Summary: 3D bioprinting is a technology that prints designed biological materials in three dimensions, with applications in producing tissues, organs, cells, and blood vessels for transplantation. It also finds uses in modeling, drug delivery systems, and drug screening. Despite limitations, this technology is of great significance in the medical field.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

Article Engineering, Biomedical

Alginate-gelatin-Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models

Salvador Flores-Torres et al.

Summary: This study demonstrates the development of patient-derived bioprinted tissue models using controlled fractions of alginate, gelatin, and Matrigel, supporting cancer spheroid growth. These engineered models can be dissociated and reprinted to generate multigenerational models, showing potential for studying patient drug response in vivo.

BIOFABRICATION (2021)

Review Cell Biology

Factors to consider when interrogating 3D culture models with plate readers or automated microscopes

Terry Riss et al.

Summary: With the increase in use of physiologically relevant three-dimensional cell culture models, researchers must validate new assay methods and consider the challenges posed by the complexity and size of cell structures to ensure the accuracy and reliability of the assays.

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2021)

Article Plant Sciences

Cell suspension culture extract of Eriobotrya japonica attenuates growth and induces apoptosis in prostate cancer cells via targeting SREBP-1/FASN-driven metabolism and AR

Po-Fan Hsieh et al.

Summary: The study demonstrates that the cell suspension culture extract from Eriobotrya japonica (EJCE) shows significant anticancer efficacy in prostate cancer cells, including castration-resistant prostate cancer. EJCE inhibits lipogenesis-related factors, reduces intracellular fatty acid levels, induces apoptosis, and suppresses tumor growth in a xenograft mouse model, suggesting its potential as a novel therapeutic approach for aggressive prostate cancer.

PHYTOMEDICINE (2021)

Review Chemistry, Physical

A Review on the Adaption of Alginate-Gelatin Hydrogels for 3D Cultures and Bioprinting

Magdalena B. Labowska et al.

Summary: Hydrogels are excellent materials for 3D cell cultures, providing appropriate microenvironments that mimic extracellular matrix functions. Sodium alginate-based hydrogel is commonly used and often combined with gelatin. In 3D printing technology, hydrogels can be used as inks to accurately manufacture scaffolds with complex shapes and geometries.

MATERIALS (2021)

Review Pharmacology & Pharmacy

Generation and analysis of 3D cell culture models for drug discovery

Lisa Belfiore et al.

Summary: 3D cell models are considered more accurate in predicting the efficacy of drug responses and are seen as more physiologically representative tools for in vitro modeling of in vivo tissues. In the future, 3D cell models will continue to play an important role in drug discovery applications.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

Article Chemistry, Multidisciplinary

3D bioprinting of engineered breast cancer constructs for personalized and targeted cancer therapy

Majid Sharifi et al.

Summary: Bioprinting technique enables the study of biological changes in response to pharmacological compounds, specifically in breast cancer tissue for personalized medicine. Challenges in reproducibility of 3D bioprinted breast cancer tissue are mainly due to uncertainty in scaffold materials and lack of printing methods. Future applications of bioprinted cancer models may facilitate rapid and precise drug screening in breast cancer research.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Materials Science, Multidisciplinary

3D bioprinting technology to mimic the tumor microenvironment: tumor-on-a-chip concept

H. Samadian et al.

Summary: Despite advancements in cancer treatment, challenges such as recurrence, metastasis, and drug resistance persist as major global health issues. Researchers are now exploring 3D bioprinting to mimic tumor microenvironment, aiming to discover new therapeutic approaches, monitor cancer progression, and design innovative anticancer therapies.

MATERIALS TODAY ADVANCES (2021)

Article Oncology

3D Bioprinted cancer models: Revolutionizing personalized cancer therapy

Robin Augustine et al.

Summary: The use of 3D bioprinting technology in generating bioengineered tumor models offers a promising approach for personalized cancer therapy screening, by accurately mimicking the human tumor tissues and microenvironment for high-throughput drug screening.

TRANSLATIONAL ONCOLOGY (2021)

Review Biochemistry & Molecular Biology

Recent trends in natural polysaccharide based bioinks for multiscale 3D printing in tissue regeneration: A review

Balaji Mahendiran et al.

Summary: Biofabrication using 3D printing technology allows for the printing of anatomically shaped native tissues, while plant-based biomaterials can mimic the characteristics of natural tissues. The focus is currently on the applications of plant-based bioinks in 3D printing.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Public, Environmental & Occupational Health

The potential role and apoptotic profile of three medicinal plant extracts on Leishmania tropica by MIT assay, macrophage model and flow cytometry analysis

Mozhde Ilaghi et al.

Summary: The study demonstrated that leaf extracts of Quercus velutina, Calotropis procera, and Nicotiana tabacum exhibit effective antileishmanial activity and induce apoptosis against L tropica promastigotes. Further research is needed to isolate and analyze the chemical compositions and biological properties of these extracts.

PARASITE EPIDEMIOLOGY AND CONTROL (2021)

Article Chemistry, Multidisciplinary

Direct 3D Printed Biomimetic Scaffolds Based on Hydrogel Microparticles for Cell Spheroid Growth

Hua Zhang et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Article Biochemistry & Molecular Biology

3D bioprinted alginate-gelatin based scaffolds for soft tissue engineering

Dipul Chawla et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Materials Science, Biomaterials

In vitro and in vivo biocompatibility evaluation of a 3D bioprinted gelatin-sodium alginate/rat Schwann-cell scaffold

Zongxi Wu et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Article Chemistry, Multidisciplinary

Resazurin-Based Assay for Quantifying Living Cells during Alkaline Phosphatase (ALP) Release

Thanih Balbaied et al.

APPLIED SCIENCES-BASEL (2020)

Review Oncology

3D bioprinting for reconstituting the cancer microenvironment

Pallab Datta et al.

NPJ PRECISION ONCOLOGY (2020)

Review Multidisciplinary Sciences

Pre-clinical modeling of cutaneous melanoma

Vito W. Rebecca et al.

NATURE COMMUNICATIONS (2020)

Article Medicine, Research & Experimental

Reducing Doxorubicin resistance in breast cancer by liposomal FOXM1 aptamer: In vitro and in vivo

Negin Ghandhariyoun et al.

LIFE SCIENCES (2020)

Article Multidisciplinary Sciences

Benchmarking of cell type deconvolution pipelines for transcriptomics data

Francisco Avila Cobos et al.

NATURE COMMUNICATIONS (2020)

Review Engineering, Biomedical

Advancing Frontiers in Bone Bioprinting

Nureddin Ashammakhi et al.

ADVANCED HEALTHCARE MATERIALS (2019)

Review Biochemical Research Methods

3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis

Tijmen H. Booij et al.

SLAS DISCOVERY (2019)

Review Pharmacology & Pharmacy

The Pre-clinical Toolbox of Pharmacokinetics and Pharmacodynamics: in vitro and ex vivo Models

Carolina Herrera

FRONTIERS IN PHARMACOLOGY (2019)

Article Multidisciplinary Sciences

Characterization and printability of Sodium alginate -Gelatin hydrogel for bioprinting NSCLC co-culture

Arindam Mondal et al.

SCIENTIFIC REPORTS (2019)

Review Engineering, Biomedical

Breath figures in tissue engineering and drug delivery: State-of-the-art and future perspectives

Maria Teresa Calejo et al.

ACTA BIOMATERIALIA (2018)

Review Pharmacology & Pharmacy

3D bioprinting of functional tissue models for personalized drug screening and in vitro disease modeling

Xuanyi Ma et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

Article Engineering, Biomedical

Mechanical behaviour of alginate-gelatin hydrogels for 3D bioprinting

Michael Di Giuseppe et al.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2018)

Article Multidisciplinary Sciences

3D Bioprinted Human Skeletal Muscle Constructs for Muscle Function Restoration

Ji Hyun Kim et al.

SCIENTIFIC REPORTS (2018)

Review Engineering, Biomedical

3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances

Soroosh Derakhshanfar et al.

BIOACTIVE MATERIALS (2018)

Article Materials Science, Biomaterials

New strategy for design and fabrication of polymer hydrogel with tunable porosity as artificial corneal skirt

Danfeng Cao et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Article Engineering, Biomedical

Advanced Bioinks for 3D Printing: A Materials Science Perspective

David Chimene et al.

ANNALS OF BIOMEDICAL ENGINEERING (2016)

Article Medicine, Research & Experimental

Single-cell analysis: Advances and future perspectives

Emir Hodzic

BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES (2016)

Article Integrative & Complementary Medicine

The Induction of Apoptosis in A375 Malignant Melanoma Cells by Sutherlandia frutescens

Nicola B. van der Walt et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)

Review Biochemistry & Molecular Biology

Current Status of Bioinks for Micro-Extrusion-Based 3D Bioprinting

Amit Panwar et al.

MOLECULES (2016)

Article Biotechnology & Applied Microbiology

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity

Hyun-Wook Kang et al.

NATURE BIOTECHNOLOGY (2016)

Article Materials Science, Biomaterials

3D porous chitosan-alginate scaffolds promote proliferation and enrichment of cancer stem-like cells

Stephen J. Florczyk et al.

JOURNAL OF MATERIALS CHEMISTRY B (2016)

Review Materials Science, Biomaterials

Designing Biomaterials for 3D Printing

Murat Guvendiren et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)

Review Materials Science, Biomaterials

Designing Biomaterials for 3D Printing

Murat Guvendiren et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2016)

Article Multidisciplinary Sciences

Bioprinting three-dimensional cell-laden tissue constructs with controllable degradation

Zhengjie Wu et al.

SCIENTIFIC REPORTS (2016)

Review Engineering, Biomedical

Bioink properties before, during and after 3D bioprinting

Katja Hoelzl et al.

BIOFABRICATION (2016)

Review Chemistry, Analytical

High Content Imaging (HCI) on Miniaturized Three-Dimensional (3D) Cell Cultures

Pranav Joshi et al.

BIOSENSORS-BASEL (2015)

Review Biochemical Research Methods

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

Rasheena Edmondson et al.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2014)

Article Biotechnology & Applied Microbiology

Microfluidic organs-on-chips

Sangeeta N. Bhatia et al.

NATURE BIOTECHNOLOGY (2014)

Review Biotechnology & Applied Microbiology

3D bioprinting of tissues and organs

Sean V. Murphy et al.

NATURE BIOTECHNOLOGY (2014)

Article Medical Laboratory Technology

Validation of Cell-based Fluorescence Assays: Practice Guidelines from the ICSH and ICCS - Part V - Assay Performance Criteria

Brent Wood et al.

CYTOMETRY PART B-CLINICAL CYTOMETRY (2013)

Review Pharmacology & Pharmacy

Three-dimensional cell culture: the missing link in drug discovery

Susan Breslin et al.

DRUG DISCOVERY TODAY (2013)

Article Engineering, Biomedical

3D Bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels

Bin Duan et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2013)

Article Chemistry, Analytical

Plastic pillar inserts for three-dimensional (3D) cell cultures in 96-well plates

Dong Woo Lee et al.

SENSORS AND ACTUATORS B-CHEMICAL (2013)

Article Materials Science, Biomaterials

Bio-ink properties and printability for extrusion printing living cells

Johnson H. Y. Chung et al.

BIOMATERIALS SCIENCE (2013)

Review Multidisciplinary Sciences

Using Gene Expression Noise to Understand Gene Regulation

Brian Munsky et al.

SCIENCE (2012)

Article Engineering, Biomedical

A porous photocurable elastomer for cell encapsulation and culture

Sharon Gerecht et al.

BIOMATERIALS (2007)

Review Cell Biology

Capturing complex 3D tissue physiology in vitro

LG Griffith et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Article Chemistry, Multidisciplinary

Fit-for-purpose method development and validation for successful biomarker measurement

JW Lee et al.

PHARMACEUTICAL RESEARCH (2006)

Article Chemistry, Multidisciplinary

Harmonized guidelines for single-laboratory validation of methods of analysis - (IUPAC technical report)

M Thompson et al.

PURE AND APPLIED CHEMISTRY (2002)

Review Biochemical Research Methods

Flow cytometry of apoptotic cell death

I Vermes et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2000)