相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。PEG-Like Brush Polymer Conjugate of RNA Aptamer That Shows Reversible Anticoagulant Activity and Minimal Immune Response
Imran Ozer et al.
ADVANCED MATERIALS (2022)
Polyethylene Glycol-Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart
Imran Ozer et al.
ADVANCED SCIENCE (2022)
Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals
Gergely Tibor Kozma et al.
ADVANCED DRUG DELIVERY REVIEWS (2020)
Architectural Modification of Conformal PEG-Bottlebrush Coatings Minimizes Anti-PEG Antigenicity While Preserving Stealth Properties
Daniel Y. Joh et al.
ADVANCED HEALTHCARE MATERIALS (2019)
Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes
Zhiyu He et al.
JOURNAL OF CONTROLLED RELEASE (2019)
Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury
Miaad Bader et al.
NEUROBIOLOGY OF DISEASE (2019)
Tunable Thermo-Responsive Copolymers from DEGMA and OEGMA Synthesized by RAFT Polymerization and the Effect of the Concentration and Saline Phosphate Buffer on Its Phase Transition
Alejandro Ramirez-Jimenez et al.
POLYMERS (2019)
Polymer-drug conjugate therapeutics: advances, insights and prospects
Iriny Ekladious et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
Challenges and Opportunities for the Subcutaneous Delivery of Therapeutic Proteins
Michael R. Turner et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2018)
Animal models of obesity and diabetes mellitus
Maximilian Kleinert et al.
NATURE REVIEWS ENDOCRINOLOGY (2018)
C-terminal site-specific PEGylated Exendin-4 analog: A long-acting glucagon like Peptide-1 receptor agonist, on glycemic control and beta cell function in diabetic db/db mice
Daoqi Tang et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2018)
A brush-polymer/exendin-4 conjugate reduces blood glucose levels for up to five days and eliminates poly(ethylene glycol) antigenicity
Yizhi Qi et al.
NATURE BIOMEDICAL ENGINEERING (2017)
Non-linear PEG-based thermoresponsive polymer systems
Nezha Badi
PROGRESS IN POLYMER SCIENCE (2017)
One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer
Kelli M. Luginbuhl et al.
NATURE BIOMEDICAL ENGINEERING (2017)
Effect of Molecular Architecture on Cell Interactions and Stealth Properties of PEG
Imran Ozer et al.
BIOMACROMOLECULES (2017)
Glucagon-like peptide-1 receptor is present in pancreatic acinar cells and regulates amylase secretion through cAMP
Yanan Hou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2016)
Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population
Qi Yang et al.
ANALYTICAL CHEMISTRY (2016)
A Modular Method for the High-Yield Synthesis of Site-Specific Protein-Polymer Therapeutics
Yan Pang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
Nancy J. Ganson et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)
Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation
Peng Zhang et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Peptide therapeutics: current status and future directions
Keld Fosgerau et al.
DRUG DISCOVERY TODAY (2015)
PEGylated Biopharmaceuticals: Current Experience and Considerations for Nonclinical Development
Inge A. Ivens et al.
TOXICOLOGIC PATHOLOGY (2015)
Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics
Johan J. F. Verhoef et al.
DRUG DISCOVERY TODAY (2014)
In Depth Analysis on the Unusual Multistep Aggregation Process of Oligo(ethylene glycol) Methacrylate-Based Polymers in Water
Bo Zhang et al.
MACROMOLECULES (2014)
Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients
Michael S. Hershfield et al.
ARTHRITIS RESEARCH & THERAPY (2014)
Immunogenicity of Subcutaneously Administered Therapeutic Proteins-a Mechanistic Perspective
Anas M. Fathallah et al.
AAPS JOURNAL (2013)
On the Thermally Reversible Dynamic Hydration Behavior of Oligo(ethylene glycol) Methacrylate-Based Polymers in Water
Shengtong Sun et al.
MACROMOLECULES (2013)
Questioning the use of PEGylation for drug delivery
Johan J. F. Verhoef et al.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2013)
Mechanistic Determinants of Biotherapeutics Absorption Following SC Administration
Wolfgang F. Richter et al.
AAPS JOURNAL (2012)
Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents
Ricardo P. Garay et al.
EXPERT OPINION ON DRUG DELIVERY (2012)
The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide
Scott E. Kanoski et al.
NEUROPHARMACOLOGY (2012)
Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) Trials
John B. Buse et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Thermoresponsive behaviour of poly[(oligo(ethyleneglycol methacrylate)]s and their protein conjugates: importance of concentration and solvent system
Konstantinos Bebis et al.
POLYMER CHEMISTRY (2011)
Pharmacokinetics and pharmacodynamics of exenatide following alternate routes of administration
Bronislava R. Gedulin et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)
Polymerization of oligo(ethylene glycol) (meth)acrylates: Toward new generations of smart biocompatible materials
Jean-Francois Lutz
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY (2008)
Protein therapeutics: A summary and pharmacological classification
Benjamin Leader et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Size comparison between proteins PEGylated with branched and linear Poly(Ethylene glycol) molecules
Conan J. Fee
BIOTECHNOLOGY AND BIOENGINEERING (2007)
Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients
Jonathan K. Armstrong et al.
CANCER (2007)
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase
NJ Ganson et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Adjuvants and antibody production: Dispelling the myths associated with Freund's complete and other adjuvants
HF Stills
ILAR JOURNAL (2005)
Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates
P Caliceti et al.
ADVANCED DRUG DELIVERY REVIEWS (2003)
Effect of pegylation on pharmaceuticals
JM Harris et al.
NATURE REVIEWS DRUG DISCOVERY (2003)
分享论文
