相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。3D human liver spheroids for translational pharmacology and toxicology
Magnus Ingelman-Sundberg et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2022)
Gene Expression over Time during Cell Transformation Due to Non-Genotoxic Carcinogen Treatment of Bhas 42 Cells
Kiyomi Ohmori et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Analyses of Transcriptomics Cell Signalling for Pre-Screening Applications in the Integrated Approach for Testing and Assessment of Non-Genotoxic Carcinogens
Yusuke Oku et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Sorafenib reduces steatosis-induced fibrogenesis in a human3Dco-culture model of non-alcoholic fatty liver disease
Guilherme Ribeiro Romualdo et al.
ENVIRONMENTAL TOXICOLOGY (2021)
Carcinogenesis: Failure of resolution of inflammation
Anna Fishbein et al.
PHARMACOLOGY & THERAPEUTICS (2021)
Assessing chemical carcinogenicity: hazard identification, classification, and risk assessment. Insight from a Toxicology Forum state-of-the-science workshop
Susan P. Felter et al.
CRITICAL REVIEWS IN TOXICOLOGY (2021)
Primary Human Hepatocyte Spheroids as Tools to Study the Hepatotoxic Potential of Non-Pharmaceutical Chemicals
Vania Vilas-Boas et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Connexin-Based Channel Activity Is Not Specifically Altered by Hepatocarcinogenic Chemicals
Kaat Leroy et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Curcumin-enriched Gemini surfactant nanoparticles exhibited tumoricidal effects on human 3D spheroid HT-29 cells in vitro
Zohre Zibaei et al.
CANCER NANOTECHNOLOGY (2021)
Hepatocellular carcinoma (HepG2/C3A) cell-based 3D model for genotoxicity testing of chemicals
Martina Stampar et al.
SCIENCE OF THE TOTAL ENVIRONMENT (2021)
In Vitro Liver Toxicity Testing of Chemicals: A Pragmatic Approach
Andres Tabernilla et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Threshold of Toxicological Concern-An Update for Non-Genotoxic Carcinogens
Monika Batke et al.
FRONTIERS IN TOXICOLOGY (2021)
Hazard identification, classification, and risk assessment of carcinogens: too much or too little? - Report of an ECETOC workshop
Susan P. Felter et al.
CRITICAL REVIEWS IN TOXICOLOGY (2020)
Cyclophosphamide induced oxidative stress, lipid per oxidation, apoptosis and histopathological changes in rats: Protective role of boron
Mustafa Cengiz et al.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2020)
Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens
Miriam N. Jacobs et al.
ARCHIVES OF TOXICOLOGY (2020)
Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis
Natalia Siwecka et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Cancer and ER stress: Mutual crosstalk between autophagy, oxidative stress and inflammatory response
Yuning Lin et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Revealing Protein Aggregates under Thapsigargin-Induced ER Stress Using an ER-Targeted Thioflavin
Peter Verwilst et al.
ACS SENSORS (2019)
Dissecting multi drug resistance in head and neck cancer cells using multicellular tumor spheroids
Mohammad Azharuddin et al.
SCIENTIFIC REPORTS (2019)
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
Gamze Ates et al.
ARCHIVES OF TOXICOLOGY (2018)
Thresholds of Genotoxic and Non-Genotoxic Carcinogens
Takehiko Nohmi
TOXICOLOGICAL RESEARCH (2018)
A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells
Eleanor C. Wilde et al.
ARCHIVES OF TOXICOLOGY (2018)
The current limitations of in vitro genotoxicity testing and their relevance to the in vivo situation
Fabrice Nesslany
FOOD AND CHEMICAL TOXICOLOGY (2017)
Moving forward in carcinogenicity assessment: Report of an EURL ECVAM/ESTIV workshop
Raffaella Corvi et al.
TOXICOLOGY IN VITRO (2017)
Updated recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests
David Kirkland et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2016)
3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained
Michele Zanoni et al.
SCIENTIFIC REPORTS (2016)
3D organotypic HepaRG cultures as in vitro model for acute and repeated dose toxicity studies
Daniel Mueller et al.
TOXICOLOGY IN VITRO (2014)
Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T
Daniel R. Beriault et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models
Tatyana Y. Doktorova et al.
CARCINOGENESIS (2013)
Distinguishing between genotoxic and non-genotoxic hepatocarcinogens by gene expression profiling and bioinformatic pathway analysis
Seul Ji Lee et al.
SCIENTIFIC REPORTS (2013)
Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver
Tatyana Y. Doktorova et al.
ARCHIVES OF TOXICOLOGY (2012)
Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data
Tatyana Y. Doktorova et al.
ARCHIVES OF TOXICOLOGY (2012)
Discrimination of genotoxic and non-genotoxic hepatocarcinogens by statistical analysis based on gene expression profiling in the mouse liver as determined by quantitative real-time PCR
Takashi Watanabe et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2012)
Protective effect of aminoguanidine against cyclophosphamide-induced oxidative stress and renal damage in rats
Premila Abraham et al.
REDOX REPORT (2011)
Application of Key Events Analysis to Chemical Carcinogens and Noncarcinogens
Alan R. Boobis et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2009)
Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach
Lya G. Hernandez et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2009)
The carcinoGENOMICS project: Critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays
Mathieu Vinken et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2008)