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JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
α-Synuclein impairs macroautophagy: implications for Parkinson's disease
Ashley R. Winslow et al.
JOURNAL OF CELL BIOLOGY (2010)
Autophagy: cellular and molecular mechanisms
Danielle Glick et al.
JOURNAL OF PATHOLOGY (2010)
Termination of autophagy and reformation of lysosomes regulated by mTOR
Li Yu et al.
NATURE (2010)
Reduced Basal Autophagy and Impaired Mitochondrial Dynamics Due to Loss of Parkinson's Disease-Associated Protein DJ-1
Guido Krebiehl et al.
PLOS ONE (2010)
Regulation Mechanisms and Signaling Pathways of Autophagy
Congcong He et al.
ANNUAL REVIEW OF GENETICS (2009)
Involvement of ERK1/2 signaling pathway in DJ-1-induced neuroprotection against oxidative stress
Li Gu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells
Yanina Eberhard et al.
BLOOD (2009)
p62 at the Crossroads of Autophagy, Apoptosis, and Cancer
Jorge Moscat et al.
CELL (2009)
Silencing DJ-1 reveals its contribution in paraquat-induced autophagy
Rosa A. Gonzalez-Polo et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in α-Synuclein Models of Parkinson's and Lewy Body Diseases
Brian Spencer et al.
JOURNAL OF NEUROSCIENCE (2009)
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
Yun Zhong et al.
NATURE CELL BIOLOGY (2009)
DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses
Sophie Vasseur et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
Gilad Twig et al.
EMBO JOURNAL (2008)
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
Urmi Bandyopadhyay et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
Chengyu Liang et al.
NATURE CELL BIOLOGY (2008)
A block of autophagy in lysosomal storage disorders
Carmine Settembre et al.
HUMAN MOLECULAR GENETICS (2008)
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
Eva Andres-Mateos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1
Karin Goerner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation -: A novel antiapoptotic mechanism that suppresses apoptosis
Neelam Azad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
Casey M. Clements et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The iminosugar isofagomine increases the activity of N370S mutant acid β-glucosidase in Gaucher fibroblasts by several mechanisms
Richard A. Steet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The many faces of protein-protein interactions: A compendium of interface geometry
Wan Kyu Kim et al.
PLOS COMPUTATIONAL BIOLOGY (2006)
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
Chengyu Liang et al.
NATURE CELL BIOLOGY (2006)
Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1
G Ito et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Mechanism of p21Ras S-nitrosylation and kinetics of nitric oxide-mediated guanine nucleotide exchange
JY Heo et al.
BIOCHEMISTRY (2004)
Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: Effect of chemical structure and stress signals
C Chen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Crystal structure of DJ-1/RS and implication on familial Parkinson's disease
Q Huai et al.
FEBS LETTERS (2003)
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
V Bonifati et al.
SCIENCE (2003)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)