Halomonas elongata: a microbial source of highly stable enzymes for applied biotechnology

Extremophilic microorganisms, which are resistant to extreme levels of temperature, salinity, pH, etc., have become popular tools for biotechnological applications. Due to their availability and cost-efficacy, enzymes from extremophiles are getting the attention of researchers and industries in the field of biocatalysis to catalyze diverse chemical reactions in a selective and sustainable manner. In this mini-review, we discuss the advantages of Halomonas elongata as moderate halophilic bacteria to provide suitable enzymes for biotechnology. While enzymes from H. elongata are more resistant to the presence of salt compared to their mesophilic counterparts, they are also easier to produce in heterologous hosts compared with more extremophilic microorganisms. Herein, a set of different enzymes (hydrolases, transferases, and oxidoreductases) from H. elongata are showcased, highlighting their interesting properties as more efficient and sustainable biocatalysts. With this, we aim to improve the visibility of halotolerant enzymes and their uncommon properties to integrate biocatalysis in industrial set-ups.Keypoints center dot Production and use of halotolerant enzymes can be easier than strong halophilic ones.center dot Enzymes from halotolerant organisms are robust catalysts under harsh conditions.center dot Halomonas elongata has shown a broad enzyme toolbox with biotechnology applications.

Automated summary

Extremophilic microorganisms are being used as tools for biotechnological applications due to their resistance to extreme conditions. Enzymes from Halomonas elongata are suitable for biocatalysis due to their resistance to salt and ease of production. This study highlights the diverse enzymes from H. elongata and their potential as efficient and sustainable biocatalysts, aiming to integrate biocatalysis in industrial set-ups.