4.7 Article

Integrating Pharmacokinetic-Pharmacodynamic Modeling and Physiologically Based Pharmacokinetic Modeling to Optimize Human Dose Predictions for Plasmodium falciparum Malaria: a Chloroquine Case Study

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Medicine, General & Internal

Evidence of Artemisinin-Resistant Malaria in Africa

Betty Balikagala et al.

Summary: Research conducted in Northern Uganda revealed the emergence of artemisinin-resistant Plasmodium falciparum strains, with predominant mutations found in the kelch13 gene. Thirteen patients were infected with P. falciparum parasites carrying mutations in the A675V or C469Y allele, which were associated with prolonged parasite clearance half-lives.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Infectious Diseases

An in vitro toolbox to accelerate anti-malarial drug discovery and development

Susan A. Charman et al.

MALARIA JOURNAL (2020)

Article Microbiology

Pharmacokinetic-Pharmacodynamic Analysis of Spiroindolone Analogs and KAE609 in a Murine Malaria Model

Suresh B. Lakshminarayana et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)

Article Medicine, General & Internal

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

E. A. Ashley et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Biochemistry & Molecular Biology

Insights into the Role of Heme in the Mechanism of Action of Antimalarials

Jill M. Combrinck et al.

ACS CHEMICAL BIOLOGY (2013)

Article Chemistry, Multidisciplinary

The Single Crystal X-ray Structure of β-Hematin DMSO Solvate Grown in the Presence of Chloroquine, a β-Hematin Growth-Rate Inhibitor

Johandie Gildenhuys et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Review Pharmacology & Pharmacy

Pharmacokinetic-Pharmacodynamic Modeling of Antibacterial Drugs

Elisabet I. Nielsen et al.

PHARMACOLOGICAL REVIEWS (2013)

Review Infectious Diseases

Cardiotoxicity of antimalarial drugs

Nicholas J. White

LANCET INFECTIOUS DISEASES (2007)

Article Chemistry, Medicinal

Physiologically based pharmacokinetic modeling 1: Predicting the tissue distribution of moderate-to-strong bases

T Rodgers et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2005)

Article Pharmacology & Pharmacy

Inhibition of hERG K+ currents by antimalarial drugs in stably transfected HEK293 cells

M Traebert et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2004)