☆ 4.6 Article

Adiponectin-leptin ratio for the early detection of lean non-alcoholic fatty liver disease independent of insulin resistance

ANNALS OF MEDICINE (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Pharmacology & Pharmacy

Non-alcoholic Fatty Liver Disease in Children

Emir Muzurovic et al.

Summary: Non-alcoholic fatty liver disease (NAFLD) is now the most common liver disease among children. The increasing prevalence of NAFLD and its advanced form, non-alcoholic steatohepatitis (NASH), in young people parallels the rising rates of obesity and type 2 diabetes mellitus. This trend has significant long-term implications, including increased morbidity and mortality due to liver and non-liver related conditions such as cardiovascular disease and cancer. This review summarizes current knowledge on pediatric NAFLD, including its causes, complications, prevention, and treatment options.

CURRENT VASCULAR PHARMACOLOGY (2023)

添加到收藏夹

Article Gastroenterology & Hepatology

Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach?

Ramy Younes et al.

Summary: Lean Caucasian subjects with NAFLD may progress to advanced liver disease, develop metabolic comorbidities, and experience cardiovascular disease and liver-related mortality, independent of longitudinal progression to obesity and PNPLA3 genotype. These patients represent one end of a wide spectrum of phenotypic expression of NAFLD.

GUT (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease

Panu K. Luukkonen et al.

Summary: This study demonstrated that the mechanisms underlying the metabolic and genetic components of NAFLD are fundamentally different. The metabolic component is characterized by hepatic oversupply of substrates, while the genetic component is characterized by impaired hepatic mitochondrial function.

JOURNAL OF HEPATOLOGY (2022)

添加到收藏夹

Letter Gastroenterology & Hepatology

Global multi-stakeholder endorsement of the MAFLD definition

Nahum Mendez-Sanchez et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2022)

添加到收藏夹

Review Peripheral Vascular Disease

Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: a Review of Shared Cardiometabolic Risk Factors

Emir Muzurovic et al.

Summary: The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing, and it is associated with an increased risk of cardiovascular disease (CVD). The two conditions share several risk factors, such as obesity, metabolic syndrome, and type 2 diabetes. Personalized therapeutic approaches and public health policies are needed to effectively address the NAFLD epidemic.

HYPERTENSION (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

From NAFLD to MAFLD: Implications of a Premature Change in Terminology

Zobair M. Younossi et al.

Summary: The article discusses the proposal to rename NAFLD to MAFLD, highlighting the shortcomings of the new term and warning that changing the name without a comprehensive understanding may have negative implications for the field. The recommendation is to establish a true international consensus group to assess the impact and consequences of the terminology change and make recommendations based on available evidence to move the field forward.

HEPATOLOGY (2021)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Adiponectin, Leptin and Cardiovascular Disorders

Shangang Zhao et al.

Summary: The discovery of leptin and adiponectin established adipose tissue as an important endocrine organ in cardiovascular health. Normal levels of adiponectin and leptin are crucial for proper cardiovascular function, while both excess and insufficient levels may contribute to cardiovascular disorders. High levels of both adiponectin and leptin are a paradoxical factor in the pathogenesis of cardiovascular diseases.

CIRCULATION RESEARCH (2021)

添加到收藏夹

Editorial Material Gastroenterology & Hepatology

What are the clinical settings and outcomes of lean NAFLD?

Tian-Yi Ren et al.

Summary: A new study has shown that even lean individuals can develop hepatic and extrahepatic complications from nonalcoholic fatty liver disease (NAFLD). This highlights the importance of focusing on metabolic phenotypes in NAFLD assessment, rather than just BMI-based approaches.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

添加到收藏夹

Article Immunology

Higher Serum Leptin Levels are Associated with a Reduced Risk of Sarcopenia but a Higher Risk of Dynapenia Among Older Adults

Tung-Wei Kao et al.

Summary: The study found a positive association between serum leptin levels and the risk of dynapenia, while a negative association was observed with the risk of sarcopenia in both male and female elderly individuals. Further investigation is needed to understand the biological mechanisms underlying these associations.

JOURNAL OF INFLAMMATION RESEARCH (2021)

添加到收藏夹

Article Nutrition & Dietetics

Independent Dose-Response Associations between Fetuin-A and Lean Nonalcoholic Fatty Liver Disease

Chia-Wen Lu et al.

Summary: Lean NAFLD patients have higher levels of fetuin-A, while non-lean NAFLD patients do not show a significant association with fetuin-A levels. This suggests a specific association between fetuin-A and lean NAFLD.

NUTRIENTS (2021)

添加到收藏夹

Article Endocrinology & Metabolism

Low levels of total and high-molecular-weight adiponectin may predict non-alcoholic fatty liver in Korean adults

Young-Sang Kim et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2020)

添加到收藏夹

Editorial Material Endocrinology & Metabolism

Adiponectin and leptin in the diagnosis and therapy of NAFLD

Chrysoula Boutari et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Leptin/adiponectin ratio correlates with hepatic steatosis but not arterial stiffness in nonalcoholic fatty liver disease in Japanese population

Kenichiro Mikami et al.

CYTOKINE (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Adipose Tissue-Liver Cross Talk in the Control of Whole-Body Metabolism: Implications in Nonalcoholic Fatty Liver Disease

Vian Azzu et al.

GASTROENTEROLOGY (2020)

添加到收藏夹

Article Endocrinology & Metabolism

Complications, morbidity and mortality of nonalcoholic fatty liver disease

Alessandro Mantovani et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2020)

添加到收藏夹

Article Endocrinology & Metabolism

Leptin, adiponectin, and their ratio as markers of insulin resistance and cardiometabolic risk in childhood obesity

Christine Frithioff-Bojsoe et al.

PEDIATRIC DIABETES (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement

Mohammed Eslam et al.

JOURNAL OF HEPATOLOGY (2020)

添加到收藏夹

Editorial Material Gastroenterology & Hepatology

From NAFLD to MAFLD: when pathophysiology succeeds

Herbert Tilg et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

添加到收藏夹

Review Gastroenterology & Hepatology

Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis

Qing Ye et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

添加到收藏夹

Article Endocrinology & Metabolism

The utility of visceral fat level measured by bioelectrical impedance analysis in predicting metabolic syndrome

Yi-Chen Lee et al.

OBESITY RESEARCH & CLINICAL PRACTICE (2020)

添加到收藏夹

Article Nutrition & Dietetics

Adiponectin-leptin Ratio is a Functional Biomarker of Adipose Tissue Inflammation

Gema Fruehbeck et al.

NUTRIENTS (2019)

添加到收藏夹

Review Gastroenterology & Hepatology

Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999-2019: a systematic review and meta-analysis

Jie Li et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2019)

添加到收藏夹

Article Endocrinology & Metabolism

Metabolic Messengers: adiponectin

Leon G. Straub et al.

NATURE METABOLISM (2019)

添加到收藏夹

Article Gastroenterology & Hepatology

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

Naga Chalasani et al.

HEPATOLOGY (2018)

添加到收藏夹

Review Gastroenterology & Hepatology

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

Zobair Younossi et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)

添加到收藏夹

Editorial Material Endocrinology & Metabolism

Adiponectin-leptin ratio: A promising index to estimate adipose tissue dysfunction. Relation with obesity-associated cardiometabolic risk

Gema Fruehbeck et al.

ADIPOCYTE (2018)

添加到收藏夹

Article Endocrinology & Metabolism

Irisin and leptin concentrations in relation to obesity, and developing type 2 diabetes: A cross sectional and a prospective case-control study nested in the Normative Aging Study

Ayse Sahin-Efe et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2018)

添加到收藏夹

Article Endocrinology & Metabolism

Serum leptin and leptin resistance correlations with NAFLD in patients with type 2 diabetes

Simona Cernea et al.

DIABETES-METABOLISM RESEARCH AND REVIEWS (2018)

添加到收藏夹

Article Gastroenterology & Hepatology

Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver

Alexandra Feldman et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2017)

添加到收藏夹

Article Gastroenterology & Hepatology

Global Epidemiology of Nonalcoholic Fatty Liver Disease-Meta-Analytic Assessment of Prevalence, Incidence, and Outcomes

Zobair M. Younossi et al.

HEPATOLOGY (2016)

添加到收藏夹

Article Endocrinology & Metabolism

Body Mass Index and Risk of Nonalcoholic Fatty Liver Disease: Two Electronic Health Record Prospective Studies

A. Katrina Loomis et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)

添加到收藏夹

Review Endocrinology & Metabolism

Leptin in nonalcoholic fatty liver disease: A narrative review

Stergios A. Polyzos et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2015)

添加到收藏夹

Review Gastroenterology & Hepatology

Biomarkers of liver cell death

Akiko Eguchi et al.

JOURNAL OF HEPATOLOGY (2014)

添加到收藏夹

Article Gastroenterology & Hepatology

Ultrasonographic fatty liver indicator, a novel score which rules out NASH and is correlated with metabolic parameters in NAFLD

Stefano Ballestri et al.

LIVER INTERNATIONAL (2012)

添加到收藏夹

Article Gastroenterology & Hepatology

Fatty Liver Index and Mortality: The Cremona Study in the 15th Year of Follow-Up

Giliola Calori et al.

HEPATOLOGY (2011)

添加到收藏夹

Letter Gastroenterology & Hepatology

Nonalcoholic Fatty Liver Disease Activity Score and Brunt's Pathologic Criteria for the Diagnosis of Nonalcoholic Steatohepatitis: What Do They Mean and Do They Agree?

Stefano Ballestri et al.

HEPATOLOGY (2011)

添加到收藏夹

Letter Medicine, General & Internal

Adiponectin beyond cardiometabolic disorders

Juen-Haur Hwang et al.

JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION (2011)

添加到收藏夹

Review Endocrinology & Metabolism

Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis

Stergios A. Polyzos et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2011)

添加到收藏夹

Article Gastroenterology & Hepatology

Nonobese Population in a Developing Country Has a High Prevalence of Nonalcoholic Fatty Liver and Significant Liver Disease

Kausik Das et al.

HEPATOLOGY (2010)

添加到收藏夹

Review Physiology

Mechanisms of leptin action and leptin resistance

Martin G. Myers et al.

ANNUAL REVIEW OF PHYSIOLOGY (2008)

添加到收藏夹

Review Cell Biology

Adiponectin: a biomarker of obesity-induced insulin resistance in adipose tissue and beyond

Jin-Ying Lu et al.

JOURNAL OF BIOMEDICAL SCIENCE (2008)

添加到收藏夹

Article Clinical Neurology

Leptin: Adiponectin ratio is an independent predictor of intima media thickness of the common carotid artery

Giuseppe Danilo Norata et al.

STROKE (2007)

添加到收藏夹

Review Medicine, Research & Experimental

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

Takashi Kadowaki et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

添加到收藏夹

Article Endocrinology & Metabolism

Plasma adiponectin levels in overweight and obese Asians

WS Yang et al.

OBESITY RESEARCH (2002)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.