Bioorthogonally Assisted Phototherapy: Recent Advances and Prospects

Photoresponsive materials offer excellent spatiotemporal control over biological processes and the emerging phototherapeutic methods are expected to have significant effects on targeted cancer therapies. Recent examples show that combination of photoactivatable approaches with bioorthogonal chemistry enhances the precision of targeted phototherapies and profound implications are foreseen particularly in the treatment of disperse/diffuse tumors. The extra level of on-target selectivity and improved spatial/temporal control considerably intensified related bioorthogonally assisted phototherapy research. The anticipated growth of further developments in the field justifies the timeliness of a brief summary of the state of the art.

Automated summary

Photoresponsive materials with spatiotemporal control have significant potential in targeted cancer therapies. The combination of photoactivatable approaches with bioorthogonal chemistry enhances precision and may have profound implications in treating disperse/diffuse tumors. The intensified research in bioorthogonally assisted phototherapy is justified by the anticipated growth of further developments in the field, making a timely summary of the state of the art necessary.