期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 138, 期 7, 页码 2174-2177出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.6b00250
关键词
-
资金
- NIH [GM-097444]
- Bristol-Myers Squibb
- Department of Defense
- Catalan Government
A new transformation is presented that enables chemists to couple simple alkyl carboxylic acids with aryl zinc reagents under Ni-catalysis. The success of this reaction hinges on the unique use of redox-active esters that allow one to employ such derivatives as alkyl halides surrogates. The chemistry exhibits broad substrate scope and features a high degree of practicality. The simple procedure and extremely inexpensive nature of both the substrates and pre-catalyst (NiCl2 center dot 6H(2)O, ca. $9.5/mol) bode well for the immediate widespread adoption of this method.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据