期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 138, 期 11, 页码 3655-3658出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.6b01078
关键词
-
资金
- Robert A. Welch Foundation [F-0038]
- NIH-NIGMS [RO1-GM069445]
Chiral iridium complexes modified by SEGPHOS catalyze the 2-propanol-mediated reductive coupling of branched allylic acetates 1a-1o with formaldehyde to form primary homoallylic alcohols 2a-2o with excellent control of regio- and enantioselectivity. These processes, which rely on enantiotopic pi-facial discrimination of sigma-allyliridium intermediates, represent the first examples of enantioselective formaldehyde C-C coupling beyond aldol addition.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据