4.4 Article

Hydroxychloroquine protects against autoimmune premature ovarian insufficiency by modulating the Treg/Th17 cell ratio in BALB/c mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Obstetrics & Gynecology

Synthesis, Regulatory Factors, and Signaling Pathways of Estrogen in the Ovary

Chuyu Xiao et al.

Summary: This article summarizes the current knowledge of estrogen synthesis in the ovaries, detailing the factors and signaling pathways that regulate estrogen synthesis. Understanding these regulating factors and mechanisms related to estrogen synthesis is beneficial for understanding estrogen-related disorders and may provide new therapeutic targets.

REPRODUCTIVE SCIENCES (2023)

Review Biochemistry & Molecular Biology

T cell receptor signaling in the differentiation and plasticity of CD4+T cells

Heikrujam Thoihen Meitei et al.

Summary: CD4+ T cells are critical components of the adaptive immune system that are shaped by TCR and co-receptor signaling cascades. TCR signaling plays a crucial role in T cell development, antigen recognition, activation, and differentiation. Dysregulated TCR signaling can lead to autoimmune diseases with organ-specific inflammation and tissue damage. Understanding the mechanism of TCR signal amplification will aid in developing therapeutic strategies for inflammation and autoimmune diseases. This review focuses on the role of the TCR signaling cascade and its components in the activation, differentiation, and plasticity of various CD4+ T cell subsets.

CYTOKINE & GROWTH FACTOR REVIEWS (2023)

Review Biochemistry & Molecular Biology

Autoimmune Diseases in Patients with Premature Ovarian Insufficiency-Our Current State of Knowledge

Anna Szeliga et al.

Summary: Premature ovarian insufficiency (POI) refers to the loss of ovarian function before the age of 40, with symptoms such as menstrual issues, hot flushes, and sleep disturbances. Approximately 4-30% of cases may have an autoimmune origin.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Endocrinology & Metabolism

Current Understanding of the Etiology, Symptomatology, and Treatment Options in Premature Ovarian Insufficiency (POI)

Bunpei Ishizuka

Summary: POI affects at least 1% of women and can have lifelong health problems and psychological stress. Hormone replacement therapy is recommended to alleviate symptoms and prevent complications. Further research is needed to understand the genetic background and improve infertility treatment for POI patients.

FRONTIERS IN ENDOCRINOLOGY (2021)

Article Obstetrics & Gynecology

Menopausal symptoms in women with premature ovarian insufficiency: prevalence, severity, and associated factors

Yizhou Huang et al.

Summary: Women with premature ovarian insufficiency (POI) experience a high prevalence of menopausal symptoms, particularly related to psychological and sexual domains. They are more likely to have distressing symptoms such as fatigue and mood swings compared to women with natural menopause. Living in urban areas and higher gravidity are independently associated with menopausal symptoms in women with POI.

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2021)

Review Rheumatology

Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

Eva Schrezenmeier et al.

NATURE REVIEWS RHEUMATOLOGY (2020)

Review Emergency Medicine

Acute chloroquine and hydroxychloroquine toxicity: A review for emergency clinicians

Alessandra Della Porta et al.

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2020)

Article Biochemistry & Molecular Biology

Adoptive transfers of CD4+CD25+Tregs partially alleviate mouse premature ovarian insufficiency

Dan Liu et al.

MOLECULAR REPRODUCTION AND DEVELOPMENT (2020)

Article Immunology

Decreased effector regulatory T cells and increased activated CD4+ T cells in premature ovarian insufficiency

Mutsumi Kobayashi et al.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2019)

Article Obstetrics & Gynecology

Premature ovarian insufficiency and autoimmune diseases

Noam Domniz et al.

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY (2019)

Review Genetics & Heredity

Premature ovarian insufficiency (POI) and autoimmunity-an update appraisal

Michal Kirshenbaum et al.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2019)

Editorial Material Obstetrics & Gynecology

Menopausal urogenital changes: welcome expansion of management options over the past 25 years

Gloria Bachmann

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2018)

Review Immunology

Sex Hormones in Acquired Immunity and Autoimmune Disease

Vaishali R. Moulton

FRONTIERS IN IMMUNOLOGY (2018)

Review Obstetrics & Gynecology

Hormone replacement therapy in young women with primary ovarian insufficiency and early menopause

Shannon D. Sullivan et al.

FERTILITY AND STERILITY (2016)

Article Obstetrics & Gynecology

ESHRE Guideline: management of women with premature ovarian insufficiency

L. Webber et al.

HUMAN REPRODUCTION (2016)

Article Reproductive Biology

Hydroxychloroquine attenuates cigarette smoke induced autophagic signaling in the mouse ovary

H. C. Furlong et al.

REPRODUCTIVE TOXICOLOGY (2016)

Review Immunology

Autophagy Beyond Intracellular MHC Class II Antigen Presentation

Christian Muenz

TRENDS IN IMMUNOLOGY (2016)

Review Immunology

TCR signal quantitiy and quality in CD4+ T cell differentiation

Noah J. Tubo et al.

TRENDS IN IMMUNOLOGY (2014)

Review Allergy

Modulating Toll-like Receptor 7 and 9 Responses as Therapy for Allergy and Autoimmunity

Damir Matesic et al.

CURRENT ALLERGY AND ASTHMA REPORTS (2012)

Article Immunology

Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells

Jamie M. Ireland et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2011)

Article Immunology

Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines

Alenka Kuznik et al.

JOURNAL OF IMMUNOLOGY (2011)

Article Immunology

TLR-mediated stimulation of APC: Distinct cytokine responses of B cells and dendritic cells

Tom A. Barr et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2007)