期刊
AMERICAN JOURNAL OF PERINATOLOGY
卷 -, 期 -, 页码 -出版社
THIEME MEDICAL PUBL INC
DOI: 10.1055/a-2109-4109
关键词
ROM; GBS; neonatal outcomes; ventilatory support
This retrospective cohort study aimed to evaluate the effects of prolonged rupture of membranes (ROMs) on perinatal outcomes. The study found that neonates born after ROM = 24 hours were more likely to require mechanical ventilation and continuous positive airway pressure. Additionally, infants born to Group-B Streptococcus-negative women with ROM = 24 hours had a higher risk of neonatal respiratory distress. Further investigations are needed to understand the association.
Objective The effects of prolonged rupture of membranes (ROMs) on perinatal outcomes are still unclear, and it remains controversial for the management of those labors. This study aims to evaluate how the exposure of pregnant women to a prolonged ROM ( = 24 hours) affects maternal and neonatal outcomes.Study Design This retrospective cohort study included singleton pregnant women at term delivering between January 2019 and March 2020 in a tertiary hospital. All relevant sociodemographic, pregnancy, and perinatal variables (maternal age, pre pregnancy body mass index, labor, and delivery outcomes) were collected anonymously. Data were compared between the ROM <24 hours and ROM = 24 hours study groups.Results A total of 2,689 dyads were included in the study and divided according to their ROM-delivery time: ROM <24 hours (2,369 women, 88.1%), and ROM = 24 hours (320 women, 11.9%). Maternal baseline characteristics were comparable except for the rate of nulliparous women, which was significantly higher among patients with ROM = 24 hours. No significant differences were found regarding infectious neonatal outcomes. However, mechanical ventilation and continuous positive airway pressure were more common among neonates born after ROM = 24 hours. The greater likelihood of neonatal respiratory distress was also confirmed among infants born to Group-B Streptococcus-negative women with ROM = 24 hours (15 out of 267 neonates, 5.6% vs. 52 out of 1,529 with ROM < 24 hours, 3.4%, p = 0.04).Conclusion According to the actual expectant policy, prolonged ROM is associated with an increased risk of respiratory support in noninfected neonates. Further investigations are required to explain such an association.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据