4.3 Article

CE: Tumor Lysis Syndrome: An Oncologic Emergency

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AMERICAN JOURNAL OF NURSING
卷 123, 期 3, 页码 30-35

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LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.NAJ.0000920996.75505.c2

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cancer; hyperkalemia; hyperphosphatemia; hyperuricemia; hypocalcemia; oncologic emergency; tumor lysis syndrome

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Tumor lysis syndrome is a medical emergency caused by the release of intracellular material from the breakdown of tumor cells, leading to electrolyte imbalances and potentially life-threatening complications. Nurses play a crucial role in identifying at-risk patients and managing their treatment to prevent complications and improve outcomes.
Tumor lysis syndrome is an oncologic emergency caused by the release of intracellular material, such as potassium, phosphate, and nucleic acids, into the bloodstream from the disintegration (lysis) of tumor cells. This condition, which is characterized by electrolyte imbalances, can be life-threatening, causing arrhythmias, seizures, acute kidney injury, and multiple organ failure. The prevention and treatment of tumor lysis syndrome requires immediate recognition of patients at risk for its development. With this knowledge, nurses can better manage and monitor treatments, thereby preventing complications and achieving better patient outcomes.

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