4.5 Article

Impact of Clostridioides difficile length of treatment on rates of recurrence in patients on concurrent antibiotics

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Infectious Diseases

Oral Vancomycin Prophylaxis for Primary and Secondary Prevention of Clostridioides difficile Infection in Patients Treated with Systemic Antibiotic Therapy: A Systematic Review, Meta-Analysis and Trial Sequential Analysis

Alberto Enrico Maraolo et al.

Summary: This study evaluated the efficacy and safety of oral vancomycin prophylaxis (OVP) in preventing Clostridioides difficile infection (CDI) in high-risk subjects undergoing systemic antibiotic therapy (SAT) through a systematic review and meta-analysis. The results showed that OVP had a strong protective effect against CDI occurrence. However, more data from randomized controlled trials (RCTs) are needed to establish OVP as good clinical practice.

ANTIBIOTICS-BASEL (2022)

Article Infectious Diseases

How can patients with Clostridioides difficile infection on concomitant antibiotic treatment be best managed

Fidelma Fitzpatrick et al.

Summary: Antibiotics are significant risk factors for CDI due to their impact on the gut microbiome. Managing CDI patients taking non-CDI antibiotics is challenging and can affect treatment outcomes and recurrence risk. Minimizing antibiotic use and switching to low-risk classes is recommended. Fidaxomicin may be preferred over vancomycin, but access may be limited. Prolonging anti-CDI therapy duration and concerns about microbiome disruption have insufficient evidence. Bezlotoxumab may be considered for high-risk recurrent CDI patients, but evidence is limited. Investigational approaches to minimize gut microbiome disruption from concomitant antibiotic use may enhance CDI treatment efficacy in the future.

LANCET INFECTIOUS DISEASES (2022)

Article Public, Environmental & Occupational Health

Hospital-acquired Clostridioides difficile infections in Alberta: The validity of laboratory-identified event surveillance versus clinical infection surveillance

Jessalyn Almond et al.

AMERICAN JOURNAL OF INFECTION CONTROL (2020)

Article Public, Environmental & Occupational Health

Attributable costs and length of stay of hospital-acquired Clostridioides difficile: A population-based matched cohort study in Alberta, Canada

Jenine R. Leal et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2019)

Meeting Abstract Critical Care Medicine

OUTCOMES IN PROLONGED TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTIONS WITH CONCURRENT ANTIBIOTIC USE

Mathew Johnson et al.

CRITICAL CARE MEDICINE (2018)

Article Public, Environmental & Occupational Health

Risk factors for Clostridium difficile infections-an overview of the evidence base and challenges in data synthesis

Paul Eze et al.

JOURNAL OF GLOBAL HEALTH (2017)

Article Immunology

Incidence and Costs of Clostridium difficile Infections in Canada

Adrian R. Levy et al.

OPEN FORUM INFECTIOUS DISEASES (2015)

Article Microbiology

Meta-Analysis of Antibiotics and the Risk of Community-Associated Clostridium difficile Infection

Kevin A. Brown et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)

Article Medicine, General & Internal

Epidemiology of Community-Associated Clostridium difficile Infection, 2009 Through 2011

Amit S. Chitnis et al.

JAMA INTERNAL MEDICINE (2013)

Article Infectious Diseases

Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics

Marjolein P. M. Hensgens et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2012)

Review Medicine, General & Internal

Clostridium difficile Infection: New Insights Into Management

Sahil Khanna et al.

MAYO CLINIC PROCEEDINGS (2012)

Article Immunology

Cumulative Antibiotic Exposures Over Time and the Risk of Clostridium difficile Infection

Vanessa Stevens et al.

CLINICAL INFECTIOUS DISEASES (2011)

Article Immunology

Clinical recognition and diagnosis of Clostridium difficile infection

John G. Bartlett et al.

CLINICAL INFECTIOUS DISEASES (2008)