期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 365, 期 11, 页码 1893-1900出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.202300351
关键词
C-P bond; Diaryliodonium salts; Photochemistry; Hypervalent compounds; Synthetic methods
Arylation of various phosphines with aryl(mesityl)iodonium triflates under blue light irradiation, followed by oxidative P-N bond cleavage in the in situ generated amino phosphonium salts under hydrolytic conditions, allows for the synthesis of substituted arylphosphine oxides, arylphosphinic, and arylphosphonic amides. This method utilizes visible light as the sole promoter for C-P bond formation, is compatible with a wide range of functional groups, and can be applied for late-stage C-H functionalization of drug molecules.
Arylation of amino-, diamino- and triaminophosphines with aryl(mesityl)iodonium triflates under blue light irradiation followed by oxidative P-N bond cleavage in the insitu generated amino phosphonium salts under hydrolytic conditions represent a method for the synthesis of substituted arylphosphine oxides, arylphosphinic and arylphosphonic amides respectively. The proposed approach is based on using visible light as the only promoter for the C-P bond formation, accommodates a variety of functional groups, and can be applied to the late-stage C-H functionalization of drug molecules.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据