期刊
ADVANCED FUNCTIONAL MATERIALS
卷 -, 期 -, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adfm.202302917
关键词
covalent organic frameworks; electrochemical biosensors; organophosphorus pesticides; ultrathin nanosheets
Ultrathin nitrogen and sulfur-rich bithiazole-based COF nanosheets (COF-Bta-NSs) were developed for constructing high-performance biosensors by integrating with acetylcholinesterase (AChE) through strong supramolecular interactions. These biosensors exhibited excellent electrical conductivity and abundant edge unsaturated sites, enabling the detection of various organophosphorus pesticides with a wide detection range, ultralow detection limit, and high stability. A portable biosensing device based on commercialized screen-printed electrode (SPE) was also established, demonstrating sensitive and reliable detection of actual samples from river water and leafy vegetables.
Covalent organic frameworks (COFs) with unique structural merits show substantial potential in the construction of biosensors. However, high-performance COF-based biosensors have rarely been reported due to special requirements for electrochemical biosensing. Here, the ultrathin nitrogen and sulfur-rich bithiazole-based COF nanosheets (COF-Bta-NSs) with the thickness of approximate to 1.95 nm are developed by using an interfacial perturbation growth strategy, and are further integrated with acetylcholinesterase (AChE) through strong supramolecular interactions to construct a high-performance biosensor for organophosphorus pesticides (OPs) detection. By virtue of the excellent electrical conductivity and abundant edge unsaturated sites of COF-Bta-NSs, such unique biosensors can be used for the detection of various OPs, showing a wide detection range, ultralow detection limit, and high stability. Significantly, the portable biosensing device is further set up based on commercialized screen-printed electrode (SPE), which is sensitive and reliable with the actual samples collected from river water and leafy vegetables, confirming the practical applicability. This research provides a novel insight into the development of advanced COF-based biosensors with excellent performance for biological and environmental analysis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据