4.1 Article

Activation of trace amine-associated receptor 1 (TAAR1) transiently reduces alcohol drinking in socially housed mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

Global brain c-Fos profiling reveals major functional brain networks rearrangements after alcohol reexposure

Marzena Stefaniuk et al.

Summary: Many fundamental questions on alcohol use disorder (AUD) should be examined from the perspective of the whole brain, rather than focusing on a single brain structure. By studying c-Fos expression in a mouse model, researchers have identified changes in brain functional networks caused by alcohol drinking and reexposure. These findings suggest potential targets for pharmacotherapy and highlight the importance of understanding the networks and modules involved in addiction development.

NEUROBIOLOGY OF DISEASE (2023)

Article Biochemistry & Molecular Biology

DoseCal: a virtual calculator for dosage conversion between human and different animal species

P. Janhavi et al.

Summary: Scientists and pharmacologists often encounter errors when converting drug doses between human and animal species, leading to the development of the DoseCal conversion calculator for accurate conversions. This tool assists scientists in easily and accurately converting doses between different species.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2022)

Article Biochemistry & Molecular Biology

Activation of trace amine-associated receptor 1 attenuates nicotine withdrawal-related effects

Ruyan Wu et al.

Summary: Nicotine addiction is a major avoidable brain disorder globally, and research indicates that activating TAAR1 can alleviate the negative-reinforcing effects of nicotine withdrawal.

ADDICTION BIOLOGY (2022)

Review Biochemistry & Molecular Biology

Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies

Nina Dedic et al.

Summary: TAAR1 has emerged as a promising therapeutic target for neuropsychiatric disorders due to its ability to modulate neurotransmission, particularly in regulating dopamine. Agonist compounds targeting TAAR1 have shown potential as treatments for schizophrenia and other disorders. Clinical trial data, along with preclinical findings, provide a rationale for further exploration and development of this new pharmacological class for treating related disorders.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Biochemistry & Molecular Biology

Blood-brain barrier integrity is the primary target of alcohol abuse

Jiangping Wei et al.

Summary: Long-term alcohol consumption can damage blood-brain barrier integrity and aggravate cognitive deficits, particularly in high-risk populations. Alcohol abuse targets structural and functional proteins of the BBB, leading to oxidative stress and inflammation which worsen cognitive dysfunction.

CHEMICO-BIOLOGICAL INTERACTIONS (2021)

Review Behavioral Sciences

The IntelliCage System: A Review of Its Utility as a Novel Behavioral Platform for a Rodent Model of Substance Use Disorder

Ismail Nurul Iman et al.

Summary: The use of animal models has contributed significantly to the investigation of substance use disorder, with the IntelliCage system offering a comprehensive and potentially efficient tool for studying addiction-like traits in rodents.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2021)

Review Behavioral Sciences

IntelliCage as a tool for measuring mouse behavior-20 years perspective

Anna Kiryk et al.

BEHAVIOURAL BRAIN RESEARCH (2020)

Article Neurosciences

Nicotine and alcohol: the role of midbrain dopaminergic neurons in drug reinforcement

Carole Morel et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2019)

Review Pharmacology & Pharmacy

The Case for TAAR1 as a Modulator of Central Nervous System Function

Grazia Rutigliano et al.

FRONTIERS IN PHARMACOLOGY (2018)

Article Neurosciences

Trace Amine-Associated Receptor 1 Agonists as Narcolepsy Therapeutics

Sarah W. Black et al.

BIOLOGICAL PSYCHIATRY (2017)

Article Chemistry, Medicinal

Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists

Guido Galley et al.

ACS MEDICINAL CHEMISTRY LETTERS (2016)

Article Neurosciences

Trace Amine-Associated Receptor 1 Regulation of Methamphetamine Intake and Related Traits

John H. Harkness et al.

NEUROPSYCHOPHARMACOLOGY (2015)

Article Multidisciplinary Sciences

A Model of Alcohol Drinking under an Intermittent Access Schedule Using Group-Housed Mice

Magdalena Smutek et al.

PLOS ONE (2014)

Article Substance Abuse

Intravenous Ethanol Increases Extracellular Dopamine in the Medial Prefrontal Cortex of the LongEvans Rat

Christina J. Schier et al.

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2013)

Article Pharmacology & Pharmacy

Functional Interaction between Trace Amine-Associated Receptor 1 and Dopamine D2 Receptor

Stefano Espinoza et al.

MOLECULAR PHARMACOLOGY (2011)

Article Multidisciplinary Sciences

TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

Florent G. Revel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system

Amyaouch Bradaia et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Pharmacology & Pharmacy

Trace amine-associated receptor 1 modulates dopaminergic activity

Lothar Lindemann et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Article Pharmacology & Pharmacy

Understanding the health impact of alcohol dependence

Thomas Cargiulo

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2007)

Article Neurosciences

The effect of olanzapine on craving and alcohol consumption

Kent E. Hutchison et al.

NEUROPSYCHOPHARMACOLOGY (2006)

Article Pharmacology & Pharmacy

Primate trace amine receptor 1 modulation by the dopamine transporter

GM Miller et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)

Article Multidisciplinary Sciences

Trace amines: Identification of a family of mammalian G protein-coupled receptors

B Borowsky et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)