Target-Responsive Metal-Organic Framework Nanosystem with Synergetic Sensitive Detection and Controllable Degradation against the Pesticide Triazophos in Contaminated Samples for Environment Assessment and Food Safety

Developing sensitive practical sensors for monitoring pesticide residues in edible foods and environmental samples is vital for food safety and environmental protection. Enzyme inhibited biosensors offer effective alternative sensing strategies by using the inherent characteristics of pesticides. To further improve the degradation function of pesticide sensors, here, a target triggered porphyrin metal-organic framework (MOF)-based nanosystem was designed with the synergetic bifunction of sensitive detection and controllable degradation of the triazophos pesticide. As a result of triazophos-inhibited glutathione consumption, the MOF collapsed and released the ligand porphyrin, leading to the recovery of fluorescence and photosensitization of the free porphyrin. The fluorescence recovery resulted in a sensitive detection limit of 0.6 ng mL-1 for triazophos, which was also applied for the determination of contaminated samples and bioaccumulation in rice. Furthermore, the target-activated photocatalytic ability of porphyrin endowed the system with the ability to effectively generate reactive oxygen species for degrading triazophos with a removal rate of similar to 85%, achieving eco-friendly synergetic detection and photodegradation in a controllable way. Therefore, the intelligent multifunctional MOF system demonstrated the potential of programmable systems for jointly controllable tracking and elimination of pesticide residues in the environment and opened a new avenue for designing a precise mechanism for stimulus-triggered degradation of pesticide residues accompanied by sensitive detection for environmental friendliness and food safety.

Automated summary

Developing sensitive practical sensors for monitoring pesticide residues in edible foods and environmental samples is of vital importance for food safety and environmental protection. In this study, a target triggered porphyrin metal-organic framework (MOF)-based nanosystem was designed with the dual functionality of sensitive detection and controllable degradation of the triazophos pesticide. The intelligent multifunctional MOF system demonstrated the potential of programmable systems for jointly controllable tracking and elimination of pesticide residues in the environment, providing a new pathway for designing a precise mechanism for stimulus-triggered degradation of pesticide residues accompanied by sensitive detection for environmental friendliness and food safety.