4.8 Article

Feasibility of Coacervate-Like Nanostructure for Instant Drug Nanoformulation

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Article Chemistry, Physical

Enzymatic cascade reaction in simple-coacervates

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Summary: The design of enzymatic droplet-sized reactors is an important challenge with potential applications in medical diagnostics, water purification, bioengineering, and the food industry. This study demonstrates the construction of enzymatic reactors using coacervates formed by ampholyte polymer chains stabilized with agar. The coacervates can sequester and preserve the catalytic activity of enzymes such as glucose oxidase and catalase. The study investigates the enzymatic cascade reaction within the coacervates and provides new insights into the impact of proximity and confinement on enzymatic activity.

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