SARS-CoV-2 booster effect and waning immunity in hemodialysis patients: A cohort study

Article Immunology

Towards a population-based threshold of protection for COVID-19 vaccines

David Goldblatt et al.

Summary: This study measured immune responses to four COVID-19 vaccines and found a significant correlation between IgG anti-Spike antibodies and neutralization of the virus, as well as protection against infection. The protective threshold for each vaccine was calculated, providing a potential method for evaluating the efficacy of new vaccines.

VACCINE (2022)

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Article Public, Environmental & Occupational Health

Waning 2-Dose and 3-Dose Effectiveness of mRNA Vaccines Against COVID-19–Associated Emergency Department and Urgent Care Encounters and Hospitalizations Among Adults During Periods of Delta and Omicron Variant Predominance — VISION Network, 10 States, August 2021–January 2022

Jill M. Ferdinands et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2022)

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Article Urology & Nephrology

SARS-CoV-2 Antibody Response After a Third Dose of the BNT162b2 Vaccine in Patients Receiving Maintenance Hemodialysis or Peritoneal Dialysis

Ilias Bensouna et al.

Summary: The effectiveness of a third dose of the BNT162b2 vaccine in patients undergoing dialysis treatment was investigated, and it was found that the third dose significantly increased antibody levels.

AMERICAN JOURNAL OF KIDNEY DISEASES (2022)

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Article Immunology

BNT162b2 Booster Vaccination Induced Immunity against SARS-CoV-2 Variants among Hemodialysis Patients

Michal Herman-Edelstein et al.

Summary: This study aimed to evaluate the effectiveness of the BNT162b2 vaccine booster against the spread of coronavirus variants in a hemodialysis population. The results showed that the booster dose can improve humoral and cell-mediated immunity, but has an inferior effect against the Omicron variant. In addition, a second booster dose can reduce breakthrough infections.

VACCINES (2022)

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Letter Medicine, General & Internal

Antibody Titers After a Third and Fourth SARS-CoV-2 BNT162b2 Vaccine Dose in Older Adults

Noa Eliakim-Raz et al.

JAMA NETWORK OPEN (2022)

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Article Public, Environmental & Occupational Health

Long-term humoral immunity decline in hemodialysis patients following severe acute respiratory syndrome coronavirus 2 vaccination: A cohort study

Eibhlin Goggins et al.

Summary: Dialysis patients who received the BNT162b2 vaccine showed a significant decline in long-term immunity. At 6 months post-vaccination, 40% of patients had negative or borderline antibody levels. These findings underscore the urgent need for vaccine boosters in this patient population.

HEALTH SCIENCE REPORTS (2022)

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Article Transplantation

Haemodialysis patients show a highly diminished antibody response after COVID-19 mRNA vaccination compared with healthy controls

Benedikt Simon et al.

Summary: HD patients had significantly lower anti-SARS-CoV-2 S antibody titres compared to controls 21 days after vaccination. The HD group experienced fewer adverse events than the control group. There was no correlation between the antibody response to Hepatitis B vaccination and the SARS-CoV-2 vaccine.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

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SARS-CoV-2 booster effect and waning immunity in hemodialysis patients: A cohort study

相关参考文献

Towards a population-based threshold of protection for COVID-19 vaccines

Waning 2-Dose and 3-Dose Effectiveness of mRNA Vaccines Against COVID-19–Associated Emergency Department and Urgent Care Encounters and Hospitalizations Among Adults During Periods of Delta and Omicron Variant Predominance — VISION Network, 10 States, August 2021–January 2022

SARS-CoV-2 Antibody Response After a Third Dose of the BNT162b2 Vaccine in Patients Receiving Maintenance Hemodialysis or Peritoneal Dialysis

BNT162b2 Booster Vaccination Induced Immunity against SARS-CoV-2 Variants among Hemodialysis Patients

Antibody Titers After a Third and Fourth SARS-CoV-2 BNT162b2 Vaccine Dose in Older Adults

Long-term humoral immunity decline in hemodialysis patients following severe acute respiratory syndrome coronavirus 2 vaccination: A cohort study

Haemodialysis patients show a highly diminished antibody response after COVID-19 mRNA vaccination compared with healthy controls

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