4.2 Article

Redox-Responsive Hyaluronic Acid-Tacrolimus Conjugate: Synthesis, Characterization, and In Vitro Immunosuppressive Activity

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Tailored Trojan horse nanocarriers for enhanced redox-responsive drug delivery

Yaru Li et al.

Summary: A tailored Trojan horse nanocarrier with pH-labile zeolitic imidazolate framework-8 (ZIF-8) as the core and disulfide-linked amphiphilic polymer-drug conjugate as the steric shell is designed. The nanocarrier exhibits improved drug release and therapeutic efficacy through the collapse of ZIF-8 under low pH conditions, inducing the liberation and further cleavage of the drug.

JOURNAL OF CONTROLLED RELEASE (2022)

Review Chemistry, Multidisciplinary

Antibody drug conjugates in gastrointestinal cancer: From lab to clinical development

Davinder Singh et al.

Summary: ADCs, a rapidly growing class of biotherapeutics in oncology, are still in early stages of clinical application for gastrointestinal cancers with limited success. Research is being conducted to develop a new generation of ADCs against gastrointestinal cancers by improving key components and focusing on technical advancements.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Chemistry, Multidisciplinary

Pharmacokinetic Assessment of Rottlerin from Mallotus philippensis Using a Highly Sensitive Liquid Chromatography-Tandem Mass Spectrometry-Based Bioanalytical Method

Diksha Manhas et al.

Summary: Rottlerin, a bioactive phytoconstituent in Mallotus philippensis, showed promising pharmacological actions against cancer with drug-like properties in vitro, displaying excellent half-life and oral bioavailability compared to other natural phenolics. The study provided valuable information for further development of rottlerin as a phytotherapeutic agent for cancer therapy.

ACS OMEGA (2021)

Review Food Science & Technology

Macrolides: From Toxins to Therapeutics

Kiersten D. Lenz et al.

Summary: Macrolides are a diverse class of compounds characterized by a macrocyclic lactone ring and variable side chains or groups. While some macrolides are toxins that disrupt natural cellular processes, others have therapeutic properties.

TOXINS (2021)

Article Pharmacology & Pharmacy

Colon-targeted delivery of tacrolimus using pH-responsive polymeric nanoparticles for murine colitis therapy

Xiaoran Cai et al.

Summary: The study successfully developed an oral nanoparticle delivery system for the effective treatment of inflammatory bowel disease by preparing FK506/HP-β-CD inclusion compounds and adsorbing ES100 and HA onto the nanoparticles loaded with FK506/HP-β-CD through electrostatic interactions. FK506@EHCh NPs displayed promising results in suppressing inflammation and showed potential for targeted treatment of inflammatory bowel disease.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

Article Biochemistry & Molecular Biology

ROS-Responsive Nanoparticles for Suppressing the Cytotoxicity and Immunogenicity Caused by PM2.5 Particulates

Yixian Zhang et al.

BIOMACROMOLECULES (2019)

Article Pharmacology & Pharmacy

Pharmacokinetics of topically applied tacrolimus dissolved in Marinosolv, a novel aqueous eye drop formulation

Cornelia Siegl et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

Review Biotechnology & Applied Microbiology

Polymer-drug conjugate therapeutics: advances, insights and prospects

Iriny Ekladious et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Review Pharmacology & Pharmacy

Cathepsin-sensitive nanoscale drug delivery systems for cancer therapy and other diseases

Divya Dheer et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Article Nanoscience & Nanotechnology

Gold Nano-/Microroses on Levodopa Microtubes for SERS-Based Sensing of Gliomas

Taru Dube et al.

ACS APPLIED NANO MATERIALS (2019)

Article Biochemistry & Molecular Biology

In Situ Probing Intracellular Drug Release from Redox-Responsive Micelles by United FRET and AIE

Xuelin Wang et al.

MACROMOLECULAR BIOSCIENCE (2018)

Article Chemistry, Multidisciplinary

Tacrolimus Loaded PEG-Cholecalciferol Based Micelles for Treatment of Ocular Inflammation

Shallu Kutlehria et al.

PHARMACEUTICAL RESEARCH (2018)

Review Biotechnology & Applied Microbiology

Advances in redox-responsive drug delivery systems of tumor microenvironment

Xiaoshuang Guo et al.

JOURNAL OF NANOBIOTECHNOLOGY (2018)

Review Polymer Science

Hyaluronic Acid-Based Nanomaterials for Cancer Therapy

Jin Hong Kim et al.

POLYMERS (2018)

Article Integrative & Complementary Medicine

An in vivo immunomodulatory and anti-inflammatory study of fermented Dendropanax morbifera Leveille leaf extract

Biruk Tesfaye Birhanu et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2018)

Review Pharmacology & Pharmacy

Polysaccharides based nanomaterials for targeted anti-cancer drug delivery

Divya Dheer et al.

JOURNAL OF DRUG TARGETING (2017)

Article Immunology

Glutathione Primes T Cell Metabolism for Inflammation

Tak W. Mak et al.

IMMUNITY (2017)

Article Chemistry, Multidisciplinary

Preformulation of FK506 Prodrugs for Improving Solubility

Young-Guk Na et al.

BULLETIN OF THE KOREAN CHEMICAL SOCIETY (2016)

Article Nanoscience & Nanotechnology

Triggered-release polymeric conjugate micelles for on-demand intracellular drug delivery

Yanwu Cao et al.

NANOTECHNOLOGY (2015)

Article Multidisciplinary Sciences

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS

Touraj Shokati et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2015)

Review Gastroenterology & Hepatology

Review on immunosuppression in liver transplantation

Maryam Moini et al.

WORLD JOURNAL OF HEPATOLOGY (2015)

Article Integrative & Complementary Medicine

Immunomodulatory effect of an isolated fraction from Tinospora crispa on intracellular expression of INF-γ, IL-6 and IL-8

Walaa Najm Abood et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)

Review Urology & Nephrology

Calcineurin Inhibitor Nephrotoxicity: A Review and Perspective of the Evidence

Naim Issa et al.

AMERICAN JOURNAL OF NEPHROLOGY (2013)

Article Immunology

Calcineurin Inhibitors: 40 Years Later, Can't Live Without

Jamil R. Azzi et al.

JOURNAL OF IMMUNOLOGY (2013)

Article Medicine, Research & Experimental

Cathepsin B Degradable Star-Shaped Peptidic Macromolecules for Delivery of 2-Methoxyestradiol

Ravi Shankar et al.

MOLECULAR PHARMACEUTICS (2013)

Review Chemistry, Physical

Stimuli-responsive nanocarriers for drug delivery

Simona Mura et al.

NATURE MATERIALS (2013)

Article Biotechnology & Applied Microbiology

PharmGKB summary: cyclosporine and tacrolimus pathways

Julia M. Barbarino et al.

PHARMACOGENETICS AND GENOMICS (2013)

Article Pharmacology & Pharmacy

Self micro-emulsifying drug delivery system of tacrolimus: Formulation, in vitro evaluation and stability studies

Pranav V. Patel et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2013)

Review Chemistry, Physical

Polymeric Conjugates for Drug Delivery

Nate Larson et al.

CHEMISTRY OF MATERIALS (2012)

Article Pharmacology & Pharmacy

Tacrolimus-loaded ethosomes: Physicochemical characterization and in vivo evaluation

Guiling Li et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2012)

Review Pharmacology & Pharmacy

Formulation strategies for drug delivery of tacrolimus: An overview

Pranav Patel et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION (2012)

Review Urology & Nephrology

Calcineurin Inhibitor Nephrotoxicity

Maarten Naesens et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)

Review Biochemistry & Molecular Biology

Glutathione: Overview of its protective roles, measurement, and biosynthesis

Henry Jay Forman et al.

MOLECULAR ASPECTS OF MEDICINE (2009)

Article Urology & Nephrology

Renal expression of CD44 correlates with acute renal allograft rejection

K. M. A. Rouschop et al.

KIDNEY INTERNATIONAL (2006)

Review Medicine, General & Internal

Immunosuppressive drugs for kidney transplantation

PF Halloran

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Biochemistry & Molecular Biology

A hyaluronic acid-taxol antitumor bioconjugate targeted to cancer cells

Y Luo et al.

BIOMACROMOLECULES (2000)