相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。
Review
Infectious Diseases
Mohamad Salim Alkodaymi et al.
Summary: This study aimed to estimate the prevalence of persistent symptoms and signs at least 12 weeks after acute COVID-19 and found that a large proportion of patients experience post-acute COVID-19 syndrome 3 to 12 months after recovery from the acute phase of COVID-19. However, available studies of post-acute COVID-19 syndrome are highly heterogeneous. Future studies need to have appropriate comparator groups, standardized symptom definitions and measurements, and longer follow-up.
CLINICAL MICROBIOLOGY AND INFECTION
(2022)
Review
Infectious Diseases
Caifang Zheng et al.
Summary: A meta-analysis showed that COVID-19 vaccines have high efficacy in real-world settings, providing significant protection against SARS-CoV-2-related diseases. Fully vaccinated individuals had vaccine effectiveness of 89.1% against infection, 97.2% against hospitalization, 97.4% against ICU admission, and 99.0% against death.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Review
Infectious Diseases
Joan B. Soriano et al.
Summary: People with COVID-19 might experience long-term symptoms known as long COVID or long-haul COVID. The lack of a standardized definition hinders the understanding and treatment of this condition. In a WHO-led Delphi process, a consensus definition was developed, stating that post-COVID-19 condition occurs in individuals with a history of SARS-CoV-2 infection, with symptoms lasting for at least 2 months and impacting everyday functioning. This common framework provides a foundation for future studies and therapy.
LANCET INFECTIOUS DISEASES
(2022)
Article
Critical Care Medicine
Priya Venkatesan
Lancet Respiratory Medicine
(2022)
Article
Immunology
Marc Scherlinger et al.
Summary: This study suggests that SARS-CoV-2 vaccination is well tolerated and immunogenic in the majority of patients with long-COVID or post-acute sequelae of COVID-19 (PASC). Disseminating these reassuring data might prove crucial to increasing vaccine coverage in patients with PASC.
Review
Microbiology
Qing Han et al.
Summary: Emerging evidence suggests that COVID-19 survivors may experience persistent symptoms for at least 12 months, including fatigue, dyspnea, arthromyalgia, depression, anxiety, memory loss, concentration difficulties, and insomnia. Female patients and those with more severe initial illness are more likely to suffer from long-term sequelae after one year.
Article
Infectious Diseases
Maddalena Peghin et al.
Summary: This study investigated the impact of vaccination and humoral responses on post-COVID-19 syndrome 1 year after the onset of SARS-CoV-2 infection. The results showed that vaccination was not associated with worsening of post-COVID-19 symptoms, while high titres of non-RBD SARS-CoV-2 IgG induced by natural infection may play a role in long-haul COVID-19.
CLINICAL MICROBIOLOGY AND INFECTION
(2022)
Letter
Infectious Diseases
Cesar Fernandez-de-las-Penas
Article
Infectious Diseases
Michela Antonelli et al.
Summary: Despite the high efficacy of COVID-19 vaccines, some individuals still become infected with SARS-CoV-2 post-vaccination. Risk factors for post-vaccination infection include frailty in older adults, living in deprived areas, and obesity. Vaccination is associated with reduced odds of severe symptoms and long-duration illness. The findings suggest the importance of targeting at-risk populations and maintaining infection control measures even in vaccinated individuals.
LANCET INFECTIOUS DISEASES
(2022)
Article
Health Care Sciences & Services
Juan P. Wisnivesky et al.
Summary: This study examined the differences in post-acute sequelae of COVID (PASC) between vaccinated and unvaccinated patients. The findings suggest that COVID vaccination is not associated with improvement in PASC.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Mayssam Nehme et al.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Review
Immunology
Chen Chen et al.
Summary: This study reveals a substantial prevalence of post-COVID-19 condition worldwide. Hospitalized patients have a higher prevalence compared to non-hospitalized ones. Fatigue is the most commonly reported symptom.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Virology
Tomoya Tsuchida et al.
Summary: This study evaluated the changes in symptoms and antibody titers in patients with Long COVID after vaccination. Some patients experienced symptom relief, while others experienced worsening. The worsened group had a higher increase in antibody titers, indicating a possible link between excessive immune response and worsening of sequelae.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ziyad Al-Aly et al.
Summary: This study analyzed the US Department of Veterans Affairs national healthcare databases to investigate the occurrence of Long COVID and death risk after breakthrough SARS-CoV-2 infection. The findings showed that vaccination significantly reduced the risk of death and post-acute sequelae but did not eliminate them completely. These results underscore the importance of further research on prevention and post-acute care for breakthrough infections.
Article
Medicine, General & Internal
Giuseppe Maglietta et al.
Summary: This study investigates the association between factors present during COVID-19 hospitalization and long-term sequelae. The findings suggest that female sex and acute disease severity may serve as independent prognostic factors. Further longitudinal studies with longer follow-up are needed to confirm these results and develop targeted prevention and management strategies for individuals at higher risk for PCS.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
William David Strain et al.
Summary: This survey suggests that COVID-19 vaccination may improve symptoms in patients with long COVID, although individual responses vary. Validation through randomized controlled trials is needed.
Article
Immunology
Maxime Taquet et al.
Summary: Vaccination against COVID-19 has been shown to reduce the risk of certain outcomes following SARS-CoV-2 infection, but not all outcomes. The age and number of vaccine doses may have an impact on the effectiveness of the vaccine.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Review
Primary Health Care
Sophie A. M. van Kessel et al.
Summary: This systematic review examines the nature and frequency of persistent symptoms in patients after mild COVID-19 infection. The findings indicate that approximately one-third of patients with mild infections experience persistent symptoms after 3 weeks. Common persistent symptoms include fatigue, dyspnea, cough, chest pain, headache, decreased cognitive function, and olfactory dysfunction. Additionally, persistent symptoms can have significant consequences on work and daily functioning.
Article
Multidisciplinary Sciences
Noah Baker et al.
News Item
Multidisciplinary Sciences
Heidi Ledford
Summary: Coronavirus vaccines help reduce the risk of developing COVID-19, but studies differ on their protective effect against long COVID.
Review
Medicine, General & Internal
Lawrence D. Hayes et al.
Summary: With the spread of the COVID-19 pandemic, more and more attention has been drawn to the persistent symptoms of long COVID, yet systematic reviews on the type and prevalence of symptoms are lacking. A study found that there are over 100 different symptoms reported in long COVID patients, with significant variations in prevalence, potentially related to unknown factors.
FRONTIERS IN MEDICINE
(2021)
Review
Medicine, General & Internal
Cesar Fernandez-de-las-Penas et al.
Summary: This meta-analysis revealed that more than 60% of patients with SARS-CoV-2 infection experienced post-COVID-19 symptoms. Fatigue and dyspnea were the most prevalent post-COVID-19 symptoms, especially at 60 and >= 90 days after onset.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2021)
News Item
Multidisciplinary Sciences
Michael Marshall
Summary: Scientists are gaining insights into the long-term effects of SARS-CoV-2 on some infected individuals, but many mysteries surrounding this issue remain unsolved.
Review
Microbiology
Amy D. Proal et al.
Summary: The novel coronavirus SARS-CoV-2 has led to a pandemic of COVID-19, with some patients developing persistent symptoms known as Long COVID or PASC. These patients may have different underlying biological factors driving their symptoms, such as organ damage, persistent viral reservoirs, re-activation of pathogens, and immune dysregulation. Therapeutic approaches may need to be individualized to effectively manage care for specific patients with PASC.
FRONTIERS IN MICROBIOLOGY
(2021)
Review
Public, Environmental & Occupational Health
Melina Michelen et al.
Summary: Long COVID is a complex condition with prolonged and heterogeneous symptoms, including weakness, general malaise, fatigue, concentration impairment, and breathlessness. Approximately 37% of patients reported reduced quality of life, and 26% of studies presented evidence of reduced pulmonary function. There is an urgent need for further studies to explore the etiology, risk factors, and biomarkers of long COVID in different populations and settings.
Article
Public, Environmental & Occupational Health
Alessandro Liberati et al.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2009)
