4.1 Article

A new detection method for canine and feline cancer using the olfactory system of nematodes

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Ants detect cancer cells through volatile organic compounds

Baptiste Piqueret et al.

Summary: Cancer is a leading cause of death worldwide. This study demonstrates that ants can be trained to detect the odor of human cancer cells, providing a noninvasive and efficient method for early cancer detection.

ISCIENCE (2022)

Review Biochemistry & Molecular Biology

Urinary Volatile Organic Compound Analysis for the Diagnosis of Cancer: A Systematic Literature Review and Quality Assessment

Qing Wen et al.

Summary: The study summarizes published literature on cancer-associated urinary volatile organic compounds, finding unique VOC profiles for different cancer subtypes and promising non-invasive diagnostic potential for cancer with urinary VOC analysis.

METABOLITES (2021)

Article Oncology

Sniffer dogs can identify lung cancer patients from breath and urine samples

Charlotte Feil et al.

Summary: The study showed that specifically trained dogs can distinguish lung cancer patients from healthy controls using urine and breath samples, especially urine samples. This method has the potential to be a simple and non-invasive tool for detecting lung cancer.

BMC CANCER (2021)

Article Multidisciplinary Sciences

C. elegans-based chemosensation strategy for the early detection of cancer metabolites in urine samples

Enrico Lanza et al.

Summary: Chemosensory receptors are crucial for organisms like the nematode Caenorhabditis elegans to accurately distinguish a wide range of volatile/soluble molecules. Through behavioral assays, it was demonstrated that the AWC sensory neurons play a significant role in cancer odorants detection, enhancing discrimination accuracy. Additionally, chemotaxis assays on animals lacking GPCRs expressed in AWC helped identify receptors involved in binding cancer metabolites, highlighting the importance of these receptors in the cancer discriminating behavior of C. elegans.

SCIENTIFIC REPORTS (2021)

Article Gastroenterology & Hepatology

Caenorhabditis elegans as a Diagnostic Aid for Pancreatic Cancer

Masanori Kobayashi et al.

Summary: The N-NOSE method showed a sensitivity of 84.6% and specificity of 60% for pancreatic cancer. It was able to detect stages 0 to I pancreatic cancer, showing a higher correlation with early-stage pancreatic cancer than advanced stage.

PANCREAS (2021)

Article Medicine, Research & Experimental

Efficiency of Gastrointestinal Cancer Detection by Nematode-NOSE (N-NOSE)

Hirotake Kusumoto et al.

IN VIVO (2020)

Article Medicine, Research & Experimental

Non-invasive cancer detection using volatile biomarkers: Is urine superior to breath?

Roland Becker

MEDICAL HYPOTHESES (2020)

Review Biochemical Research Methods

A review of exhaled breath: a key role in lung cancer diagnosis

Davide Marzorati et al.

JOURNAL OF BREATH RESEARCH (2019)

Review Pharmacology & Pharmacy

Development of an Early Cancer Detection Method Using the Olfaction of the Nematode Caenorhabditis elegans

Takayuki Uozumi et al.

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN (2019)

Article Oncology

Defining the Value of a Comparative Approach to Cancer Drug Development

Amy K. LeBlanc et al.

CLINICAL CANCER RESEARCH (2016)

Review Medical Laboratory Technology

VOC breath biomarkers in lung cancer

Yannick Saalberg et al.

CLINICA CHIMICA ACTA (2016)

Article Veterinary Sciences

2016 AAHA Oncology Guidelines for Dogs and Cats

Barb Biller et al.

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION (2016)

Article Biochemical Research Methods

Canine scent detection for the diagnosis of lung cancer in a screening-like situation

Klaus Hackner et al.

JOURNAL OF BREATH RESEARCH (2016)

Review Biology

Comparative oncology: what dogs and other species can teach us about humans with cancer

Joshua D. Schiffman et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2015)

Review Biochemistry & Molecular Biology

The scent of disease: volatile organic compounds of the human body related to disease and disorder

Mika Shirasu et al.

JOURNAL OF BIOCHEMISTRY (2011)

Article Clinical Neurology

Characteristics of compounds that cross the blood-brain barrier

William A. Banks

BMC NEUROLOGY (2009)

Review Oncology

Science and society - Translation of new cancer treatments from pet dogs to humans

Melissa Paoloni et al.

NATURE REVIEWS CANCER (2008)

Review Multidisciplinary Sciences

Comparative chemosensation from receptors to ecology

Cornelia I. Bargmann

NATURE (2006)

Article Multidisciplinary Sciences

The Ras-MAPK pathway is important for olfaction in Caenorhabditis elegans

T Hirotsu et al.

NATURE (2000)