期刊
MOLBANK
卷 2023, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/M1556
关键词
tetramic acid; enamine; pyrrolidine-2; 4-dione; antibacterial
3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione was obtained as an unexpected product in a three-step synthesis using o-nitrobenzoyl sarcosine, acetoacetanilide, and ethylamine. The compound exhibited moderate antibacterial activity against S. aureus and E. coli.
3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione was obtained as an unexpected product in a three-step synthesis starting with o-nitrobenzoyl sarcosine, acetoacetanilide and ethylamine. The compound showed moderate antibacterial activity against S. aureus and E. coli.
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