期刊
ADVANCED MATERIALS
卷 28, 期 1, 页码 161-+出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201503916
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资金
- Stanford University Canary Center Research funds [NIH R21-HL112114, 1R01EB015776, R15HL115556]
- National Science Foundation [1150733]
- Fulbright program
- Commission Franco-Americaine
- Scientific and Technical Research Council of Turkey (TUBITAK) [2214A]
- LABEX DEVweCAN of Universite de Lyon within the program Investissements d'Avenir [ANR-10-LABX-0061, ANR-11-IDEX-0007]
- Div Of Chem, Bioeng, Env, & Transp Sys
- Directorate For Engineering [1547806] Funding Source: National Science Foundation
A bio-acoustic levitational assembly method for engineering of multilayered, 3D brainlike constructs is presented. Acoustic radiation forces are used to levitate neuro-progenitors derived from human embryonic stem cells in 3D multilayered fibrin tissue constructs. The neuro-progenitor cells are subsequently differentiated in neural cells, resulting in a 3D neuronal construct with inter and intralayer neurite elongations.
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