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Cytoplasmic dynein/dynactin mediates the assembly of aggresomes
JA Johnston et al.
CELL MOTILITY AND THE CYTOSKELETON (2002)
The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans
JF Morley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
M Calfon et al.
NATURE (2002)
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
H Yoshida et al.
CELL (2001)
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
D Scheuner et al.
MOLECULAR CELL (2001)
Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation
S Nishikawa et al.
JOURNAL OF CELL BIOLOGY (2001)
Impairment of the ubiquitin-proteasome system by protein aggregation
NF Bence et al.
SCIENCE (2001)
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
M Tatar et al.
SCIENCE (2001)
Amyloid fibrils from muscle myoglobin -: Even an ordinary globular protein can assume a rogue guise if conditions are right.
M Fändrich et al.
NATURE (2001)
Initial sequencing and analysis of the human genome
ES Lander et al.
NATURE (2001)
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
J Ye et al.
MOLECULAR CELL (2000)
Regulated translation initiation controls stress-induced gene expression in mammalian cells
HP Harding et al.
MOLECULAR CELL (2000)
Age-related decline in chaperone-mediated autophagy
AM Cuervo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Partially unfolded states of β2-microglobulin and amyloid formation in vitro
VJ McParland et al.
BIOCHEMISTRY (2000)
The preaggregated state of an amyloidogenic protein: Hydrostatic pressure converts native transthyretin into the amyloidogenic state
AD Ferrao-Gonzales et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
KJ Travers et al.
CELL (2000)
Recognition of the polyubiquitin proteolytic signal
JS Thrower et al.
EMBO JOURNAL (2000)
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
H Yoshida et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy
JW Miller et al.
EMBO JOURNAL (2000)