Characteristics of renal oncocytomas and clinical novelties: Single center experience of 17 years

Objective: To assess the characteristics of renal oncocytomas and the clinical outcomes of patients in the last 17 years in our institution. Methodology: The medical records of the patients who underwent partial and radical nephrectomy from May 2004 to December 2021 were evaluated retrospectively. Radiology and pathology results were evaluated. Patients diagnosed with oncocytoma after surgery were included in the study. Results: Out of 791 patients who were operated for renal masses, 55 patients with the diagnosis of oncocytoma were included in the study, 17 of them were female. The mean age of the patients was 64.77 +/- 10.58 years. Open and laparoscopic methods were applied to patients. Partial nephrectomy was performed in 25 patients (46.2%). It was observed that none of the patients with a mean follow-up of 76 months developed recurrence or death due to oncocytoma. Conclusion: Oncocytoma is a benign and rare tumor of the kidney which distinguishing it from malign tumors preoperatively with recent techniques is impossible. Especially in small sized tumors, considering the possibility of oncocytoma, nephron sparing surgery should be preferred in terms of patients' benefit. Further research is needed for the novel imaging techniques and biomarkers proposed to be used in routine use to distinguish oncocytoma.

Automated summary

This study retrospectively assessed the characteristics and clinical outcomes of renal oncocytomas in our institution over the past 17 years. Among 791 patients who underwent nephrectomy, 55 were diagnosed with oncocytoma. The follow-up results showed no recurrence or death due to oncocytoma during an average follow-up period of 76 months.