Indian National Association for Study of the Liver (INASL) Guidance Paper on Nomenclature, Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)

Article Gastroenterology & Hepatology

FibroScan-AST (FAST) Score for Nonalcoholic Steatohepatitis - Validation in an Indian Cohort

Arka De et al.

Summary: The FAST score shows good discriminative ability for detecting NASH with significant fibrosis and inflammation in NAFLD patients. Cut-offs should be recalibrated based on disease prevalence.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2022)

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Review Gastroenterology & Hepatology

Incidence of Hepatocellular Carcinoma in Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review, Meta-analysis, and Meta-regression

Lorenzo A. Orci et al.

Summary: Nonalcoholic fatty liver disease (NAFLD) may be a risk factor for hepatocellular carcinoma (HCC), and this study used meta-analysis to analyze the incidence rates of HCC in NAFLD patients. The results showed that NAFLD patients with cirrhosis have a similar risk of developing HCC compared to cirrhosis patients with other causes. However, the incidence of HCC in nonalcoholic steatohepatitis or simple steatosis patients is lower.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2022)

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Article Medicine, Research & Experimental

Clinicopathological Profile and Outcome of a Large Cohort of Patients with Nonalcoholic Fatty Liver Disease from South Asia: Interim Results of the Indian Consortium on Nonalcoholic Fatty Liver Disease

Ajay Duseja et al.

Summary: NAFLD patients in South Asia have a higher severity of liver disease and a higher prevalence of metabolic syndrome. During follow-up, patients with compensated cirrhosis related to nonalcoholic steatohepatitis are more prone to hepatic and extrahepatic events.

METABOLIC SYNDROME AND RELATED DISORDERS (2022)

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Editorial Material Gastroenterology & Hepatology

Saroglitazar, a PPAR-α/γ Agonist, for Treatment of Nonalcoholic Fatty Liver Disease: A Randomized Controlled Double-Blind Phase 2 Trial

Manas Kumar Panigrahi et al.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2022)

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Article Gastroenterology & Hepatology

Diagnostic Accuracy and Optimal Cut-off of Controlled Attenuation Parameter for the Detection of Hepatic Steatosis in Indian Population

Mohammad S. Kuchay et al.

Summary: This study aimed to evaluate the diagnostic accuracy and optimal cut-off values of controlled attenuation parameter (CAP) in diagnosing hepatic steatosis in the Indian population. The results showed that the optimal cut-off value of CAP was 262 dB/m, which had good sensitivity and specificity in detecting mild steatosis.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2022)

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Letter Gastroenterology & Hepatology

NAFLD vs. MAFLD - It is not the name but the disease that decides the outcome in fatty liver

Arka De et al.

JOURNAL OF HEPATOLOGY (2022)

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Article Gastroenterology & Hepatology

Intragastric Balloon Placement Induces Significant Metabolic and Histologic Improvement in Patients With Nonalcoholic Steatohepatitis

Fateh Bazerbachi et al.

Summary: In a prospective study, the intragastric balloon (IGB) facilitated significant metabolic and histologic improvements in patients with NASH. The treatment appears to be safe and effective for NASH management when combined with a prescribed diet and exercise program.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Review Gastroenterology & Hepatology

AGA Clinical Practice Update on Bariatric Surgery in Cirrhosis: Expert Review

Heather Patton et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Review Gastroenterology & Hepatology

Antidiabetic drugs and non-alcoholic fatty liver disease: A systematic review, meta-analysis and evidence map

Jai Kumar et al.

Summary: The meta-analysis revealed significant efficacy of pioglitazone and novel antidiabetic agents in treating NAFLD, with pioglitazone showing remarkable improvements in liver function and steatosis.

DIGESTIVE AND LIVER DISEASE (2021)

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Article Gastroenterology & Hepatology

Improvement in insulin resistance and estimated hepatic steatosis and fibrosis after endoscopic sleeve gastroplasty

Kaveh Hajifathalian et al.

Summary: The study suggests a significant and sustained improvement in estimated hepatic steatosis and fibrosis after Endoscopic Sleeve Gastroplasty (ESG) in patients with Nonalcoholic Fatty Liver Disease (NAFLD). Importantly, an early and weight-independent improvement in insulin resistance was shown and lasted for 2 years after the procedure.

GASTROINTESTINAL ENDOSCOPY (2021)

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Article Gastroenterology & Hepatology

Non-alcoholic fatty liver disease and risk of incident diabetes mellitus: an updated meta-analysis of 501 022 adult individuals

Alessandro Mantovani et al.

Summary: This meta-analysis shows that patients with NAFLD have a significantly increased risk of developing diabetes, and this risk rises with the severity of NAFLD. The risk is independent of age, sex, adiposity measures, and other metabolic risk factors.

GUT (2021)

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Article Public, Environmental & Occupational Health

Non-alcoholic fatty liver disease in patients with hypothyroidism presenting at a rural tertiary care centre in north India

Harpreet Grewal et al.

Summary: The study revealed a significant association between hypothyroidism and the presence of NAFLD, indicating hypothyroidism as a potential risk factor for the development and progression of NAFLD.

TROPICAL DOCTOR (2021)

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Article Gastroenterology & Hepatology

Nonalcoholic Fatty Liver in Lean Individuals: Clinicobiochemical Correlates of Histopathology in 157 Liver Biopsies from Healthy Liver Donors

Narendra S. Choudhary et al.

Summary: In this study, it was found that 33.7% of lean living donors had nonalcoholic fatty liver (NAFL). Among all metabolic risk factors, only higher triglyceride levels showed a significant association with NAFL in lean donors.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2021)

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Review Gastroenterology & Hepatology

Systematic review with meta-analysis: The effect of vitamin E supplementation in adult patients with non-alcoholic fatty liver disease

Andreas Vadarlis et al.

Summary: Vitamin E supplementation can improve biochemical and histological characteristics of NAFLD patients, especially those with non-alcoholic steatohepatitis. This indicates that vitamin E may be a promising treatment option for patients with NAFLD.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Review Gastroenterology & Hepatology

Prognostic accuracy of FIB-4, NAFLD fibrosis score and APRI for NAFLD-related events: A systematic review

Jenny Lee et al.

Summary: This study synthesized the existing literature on the ability of FIB-4, NFS, and APRI models in prognosticating NAFLD-related events. The results showed that these models have demonstrated good ability to risk stratify patients for liver-related morbidity and mortality, with inconsistent performance in predicting change in fibrosis stage. Further head-to-head studies are needed to validate their performance and refine models for prognosticating NAFLD events.

LIVER INTERNATIONAL (2021)

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Article Gastroenterology & Hepatology

Impact of metabolic risk factors on the severity and outcome of patients with alcohol-associated acute-on-chronic liver failure

Ajay Duseja et al.

Summary: Metabolic risk factors, especially overweight/obesity and dyslipidaemia, exacerbate the severity of alcohol-associated acute-on-chronic liver failure (ACLF), with overweight/obesity also increasing short-term mortality in these patients.

LIVER INTERNATIONAL (2021)

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Review Gastroenterology & Hepatology

Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors

Sven Francque et al.

Summary: The global epidemic of obesity is associated with serious health consequences, including NAFLD, which can progress to liver fibrosis and cirrhosis. NAFLD is a systemic disease affecting multiple organs, with a complex pathomechanism involving PPARs as key regulators.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

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Review Gastroenterology & Hepatology

Role of Noninvasive Tests in Clinical Gastroenterology Practices to Identify Patients With Nonalcoholic Steatohepatitis at High Risk of Adverse Outcomes: Expert Panel Recommendations

Zobair M. Younossi et al.

Summary: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are common liver diseases often associated with obesity, insulin resistance, and type 2 diabetes mellitus. The stage of fibrosis is the most important predictor of liver outcomes in NAFLD and NASH, underscoring the importance of early identification of patients with advanced fibrosis.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2021)

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Article Gastroenterology & Hepatology

AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease: Expert Review

Zobair M. Younossi et al.

Summary: NAFLD is a leading cause of chronic liver disease globally, affecting over 25% of the population. Lifestyle modification for weight loss is the primary intervention for patients with NAFLD. Evidence-based interventions and best practice advice are provided for clinical management of NAFLD.

GASTROENTEROLOGY (2021)

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Article Gastroenterology & Hepatology

MRE combined with FIB-4 (MEFIB) index in detection of candidates for pharmacological treatment of NASH-related fibrosis

Jinho Jung et al.

Summary: The study demonstrated that the combination of MRE and FIB-4 showed high diagnostic accuracy in identifying patients with NAFLD who have stage 2 or higher fibrosis, making them suitable candidates for pharmacological therapy.

GUT (2021)

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Article Gastroenterology & Hepatology

FibroScan-aspartate aminotransferase score in an Asian cohort of non-alcoholic fatty liver disease and its utility in predicting histological resolution with bariatric surgery

Abhinav Anand et al.

Summary: The FibroScan-aspartate aminotransferase (FAST) score demonstrated good discrimination for fibrotic non-alcoholic steatohepatitis and correlated well with histological response to interventions for NAFLD, despite a miscalibration resulting in overprediction.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Non-alcoholic fatty liver disease: Not time for an obituary just yet!

Shivaram Prasad Singh et al.

JOURNAL OF HEPATOLOGY (2021)

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Review Gastroenterology & Hepatology

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

Daniel Q. Huang et al.

Summary: The prevalence of NAFLD-related HCC is projected to continue rising globally, with NASH expected to increase and obesity as a major risk factor. Urgent measures are needed to address this growing problem.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

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Editorial Material Gastroenterology & Hepatology

CAP for the detection of hepatic steatosis in clinical practice

Giovanna Ferraioli

LANCET GASTROENTEROLOGY & HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

Assessment of hepatic steatosis by controlled attenuation parameter using the M and XL probes: an individual patient data meta-analysis

David Petroff et al.

Summary: This study conducted an individual patient data meta-analysis to evaluate the diagnostic properties of hepatic steatosis using CAP. Results showed that optimal cutoffs for CAP varied according to different etiologies of liver disease. While CAP may not adequately grade steatosis in patients with NAFLD, it can effectively identify significant steatosis in patients with viral hepatitis.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2021)

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Review Gastroenterology & Hepatology

Therapeutic pipeline in nonalcoholic steatohepatitis

Raj Vuppalanchi et al.

Summary: The therapeutic pipeline for NASH is expanding with insights into disease pathophysiology, offering potential solutions to resolve steatohepatitis or reverse fibrosis. However, there may be some clinical challenges in the use of these emerging therapies.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

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Article Multidisciplinary Sciences

A prospective 5-year study on the use of transient elastography to monitor the improvement of non-alcoholic fatty liver disease following bariatric surgery

Shirley Yuk-Wah Liu et al.

Summary: The study found that using transient elastography for liver stiffness measurement is effective in demonstrating the improvement of liver fibrosis in obese patients undergoing bariatric surgery.

SCIENTIFIC REPORTS (2021)

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Review Gastroenterology & Hepatology

Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis

Emmanuel Anandraj Selvaraj et al.

Summary: Non-invasive tests measuring liver stiffness or using MRI have acceptable diagnostic accuracy for advanced fibrosis and cirrhosis. The potential clinical impact of these tests cannot be fully assessed due to lack of intention-to-diagnose analyses and validation of pre-specified thresholds.

JOURNAL OF HEPATOLOGY (2021)

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Review Medicine, General & Internal

Intermittent Fasting and Obesity-Related Health Outcomes An Umbrella Review of Meta-analyses of Randomized Clinical Trials

Chanthawat Patikorn et al.

Summary: This study reviewed the evidence from multiple meta-analyses of randomized clinical trials on the associations of intermittent fasting with obesity-related health outcomes. The findings showed beneficial effects of intermittent fasting on anthropometric and cardiometabolic outcomes, supported by moderate to high quality evidence.

JAMA NETWORK OPEN (2021)

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Article Medicine, General & Internal

A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis

Philip N. Newsome et al.

Summary: This phase 2 trial demonstrated that treatment with semaglutide resulted in a significantly higher percentage of patients with NASH resolution compared to placebo in patients with NASH, but did not show a significant between-group difference in the percentage of patients with an improvement in fibrosis stage.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Multidisciplinary Sciences

Two-dimensional shear wave elastography and ultrasound-guided attenuation parameter for progressive non-alcoholic steatohepatitis

Hidekatsu Kuroda et al.

Summary: This study investigated the combination of two-dimensional shear wave elastography and ultrasound-guided attenuation parameter for assessing the risk of progressive non-alcoholic steatohepatitis, showing that this combined assessment method is useful for risk stratification.

PLOS ONE (2021)

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Article Gastroenterology & Hepatology

Experience With Changing Etiology and Nontransplant Curative Treatment Modalities for Hepatocellular Carcinoma in a Real-Life Setting-A Retrospective Descriptive Analysis

Suneel Tohra et al.

Summary: The study found that viral hepatitis is the most common etiological factor for HCC in Northern India, with NASH and alcohol as etiologies increasing over time. In patients with unifocal HCC, there was no difference in overall 3-year survival between those treated with SR or RFA, but the SR group had better disease-free survival.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2021)

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Review Pharmacology & Pharmacy

Anti-diabetic drugs and NASH: from current options to promising perspectives

Sarra Smati et al.

Summary: Recent studies have shown promising effects of incretin-based therapies and PPAR agonists on NASH and T2D, highlighting the importance of targeting insulin resistance and metabolic dysfunction. However, the safety profile and limited impact on liver fibrosis of these drugs need to be further evaluated in long-term studies.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2021)

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Article Gastroenterology & Hepatology

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis-2021 update

Annalisa Berzigotti et al.

Summary: The article provides the latest update to the EASL Clinical Practice Guidelines on the use of non-invasive tests for assessing liver disease severity and prognosis, with a focus on topics with relevant evidence published in the last 5 years.

JOURNAL OF HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

New drugs for NASH

Somaya A. M. Albhaisi et al.

Summary: NASH is a form of liver disease characterized by inflammation and hepatocyte injury in the presence of hepatic steatosis, potentially leading to cirrhosis. Although weight loss and lifestyle modifications are currently the first-line treatment, the development of effective drugs for NASH is urgently needed as these methods may not be effective in advanced cases. There has been significant growth in drug development targeting pathological pathways in NASH in the past decade.

LIVER INTERNATIONAL (2021)

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Article Gastroenterology & Hepatology

Saroglitazar, a PPAR-α/γ Agonist, for Treatment of NAFLD: A Randomized Controlled Double-Blind Phase 2 Trial

Samer Gawrieh et al.

Summary: Saroglitazar showed significant efficacy in patients with NAFLD/NASH, improving ALT, liver fat content and insulin resistance. The 4mg dose of Saroglitazar also demonstrated significant improvements in lipid metabolism and lipoprotein particle composition. Overall, Saroglitazar was well-tolerated with a slight weight gain observed in patients.

HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

Comparison of Elastography Point Quantification with Transient Elastography in Patients with Chronic Viral Hepatitis and Nonalcoholic Fatty Liver Disease: A Pilot Study

Savinay Kapur et al.

Summary: This study aimed to compare the diagnostic accuracy of ElastPQ and TE with liver histology in measuring liver stiffness in patients with chronic viral hepatitis and nonalcoholic fatty liver disease. The results showed that ElastPQ and TE correlated significantly with the stage of fibrosis, but their accuracy was poor in patients with CVH and ESRD.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

Nutrition in Chronic Liver Disease: Consensus Statement of the Indian National Association for Study of the Liver

Pankaj Puri et al.

Summary: Nutrition plays a crucial role in the outcomes of patients with chronic liver disease, with malnutrition and sarcopenia being common. Timely assessment and management of nutritional status are essential to improve prognosis. The consensus statement by the Indian National Association for Study of the Liver provides comprehensive recommendations for nutritional screening and treatment in specific clinical scenarios of malnutrition in cirrhosis in both adults and children with chronic liver disease and metabolic disorders.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Changing Nomenclature from Nonalcoholic Fatty Liver Disease to Metabolic Dysfunction-Associated Fatty Liver Disease - Not Only Premature But Also Confusing

Ajay Duseja et al.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2021)

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Article Endocrinology & Metabolism

Empagliflozin Effectively Lowers Liver Fat Content in Well-Controlled Type 2 Diabetes: A Randomized, Double-Blind, Phase 4, Placebo-Controlled Trial

Sabine Kahl et al.

DIABETES CARE (2020)

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Article Surgery

Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures-2019 update: cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists

Jeffrey I. Mechanick et al.

SURGERY FOR OBESITY AND RELATED DISEASES (2020)

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Article Gastroenterology & Hepatology

Vitamin E Improves Transplant-Free Survival and Hepatic Decompensation Among Patients With Nonalcoholic Steatohepatitis and Advanced Fibrosis

Eduardo Vilar-Gomez et al.

HEPATOLOGY (2020)

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Review Gastroenterology & Hepatology

NAFLD as a driver of chronic kidney disease

Christopher D. Byrne et al.

JOURNAL OF HEPATOLOGY (2020)

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Review Endocrinology & Metabolism

Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity

Robert Ross et al.

NATURE REVIEWS ENDOCRINOLOGY (2020)

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Article Surgery

OSSI (Obesity and Metabolic Surgery Society of India) Guidelines for Patient and Procedure Selection for Bariatric and Metabolic Surgery

A. G. Bhasker et al.

OBESITY SURGERY (2020)

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Article Gastroenterology & Hepatology

FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steatohepatitis with significant activity and fibrosis: a prospective derivation and global validation study

Philip N. Newsome et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

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Letter Gastroenterology & Hepatology

FIB-4 cut-off of 1.3 may be inappropriate in a primary care referral pathway for patients with non-alcoholic fatty liver disease

Samir Shah et al.

JOURNAL OF HEPATOLOGY (2020)

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Article Gastroenterology & Hepatology

A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement

Mohammed Eslam et al.

JOURNAL OF HEPATOLOGY (2020)

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Review Gastroenterology & Hepatology

Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis

Qing Ye et al.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2020)

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Article Gastroenterology & Hepatology

Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice

Stavra A. Xanthakos et al.

GASTROENTEROLOGY (2020)

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Review Gastroenterology & Hepatology

Global epidemiology of lean non-alcoholic fatty liver disease: A systematic review and meta-analysis

Feng-Bin Lu et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2020)

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Article Gastroenterology & Hepatology

Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials

Beth A. Davison et al.

JOURNAL OF HEPATOLOGY (2020)

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Article Multidisciplinary Sciences

Saroglitazar in patients with non-alcoholic fatty liver disease and diabetic dyslipidemia: a prospective, observational, real world study

Omesh Goyal et al.

SCIENTIFIC REPORTS (2020)

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Article Primary Health Care

Prevalence of fatty liver in metabolic syndrome

Anita Goyal et al.

JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE (2020)

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Review Gastroenterology & Hepatology

The efficacy of vitamin E in reducing non-alcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression

Mohamed Abdel-Maboud et al.

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2020)

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Review Gastroenterology & Hepatology

Nonalcoholic steatohepatitis recurrence after liver transplant

Sunil Taneja et al.

TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY (2020)

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Review Gastroenterology & Hepatology

Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults: Systematic Review and Meta-Analysis

Steven Young et al.

HEPATOLOGY COMMUNICATIONS (2020)

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Article Gastroenterology & Hepatology

Endothelial Dysfunction, a Marker of Atherosclerosis, Is Independent of Metabolic Syndrome in NAFLD Patients

Jimmy Narayan et al.

INTERNATIONAL JOURNAL OF HEPATOLOGY (2020)

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Review Gastroenterology & Hepatology

Natural History of Simple Steatosis or Nonalcoholic Fatty Liver

Arka De et al.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2020)

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Article Gastroenterology & Hepatology

Correlation between insulin resistance and liver histology in patients with nonalcoholic steatohepatitis with and without obesity

Mathew Vadukoot Lazar et al.

INDIAN JOURNAL OF GASTROENTEROLOGY (2020)

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Article Gastroenterology & Hepatology

Role of Magnetic Resonance Imaging in the Monitoring of Patients with Nonalcoholic Fatty Liver Disease: Comparison with Ultrasonography, Lipid Profile, and Body Mass Index

Nikhil Makhija et al.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2020)

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Article Gastroenterology & Hepatology

Explant liver evaluation decodes the mystery of cryptogenic cirrhosis!

Mayank Jain et al.

JGH OPEN (2020)

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Review Gastroenterology & Hepatology

Extra-Hepatic Manifestations of Nonalcoholic Fatty Liver Disease: A Review

Raseen Tariq et al.

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY (2020)

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Article Immunology

Fibroscan as a non-invasive predictor of hepatic steatosis in women with polycystic ovary syndrome

Semanti Chakraborty et al.

INDIAN JOURNAL OF MEDICAL RESEARCH (2020)

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Article Gastroenterology & Hepatology

Body mass index-based controlled attenuation parameter cut-offs for assessment of hepatic steatosis in non-alcoholic fatty liver disease

Shalimar et al.

INDIAN JOURNAL OF GASTROENTEROLOGY (2020)

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Review Gastroenterology & Hepatology

Epidemiology of non-alcoholic and alcoholic fatty liver diseases

Souveek Mitra et al.

TRANSLATIONAL GASTROENTEROLOGY AND HEPATOLOGY (2020)

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Article Gastroenterology & Hepatology

Metabolic syndrome is not uncommon among lean non-alcoholic fatty liver disease patients as compared with those with obesity

Nirmalya Sinha et al.

INDIAN JOURNAL OF GASTROENTEROLOGY (2020)

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Article Gastroenterology & Hepatology

Vibration-Controlled Transient Elastography to Assess Fibrosis and Steatosis in Patients With Nonalcoholic Fatty Liver Disease

Mohammad S. Siddiqui et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

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Review Gastroenterology & Hepatology

Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual Participants

Cynthia Hsu et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)

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Article Clinical Neurology

Non-alcoholic fatty liver disease is an independent risk factor for inflammation in obstructive sleep apnea syndrome in obese Asian Indians

Surya Prakash Bhatt et al.

SLEEP AND BREATHING (2019)

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Article Gastroenterology & Hepatology

EASL Clinical Practice Guidelines on nutrition in chronic liver disease

JOURNAL OF HEPATOLOGY (2019)

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Review Endocrinology & Metabolism

Beneficial effects of SGLT2 inhibitors on fatty liver in type 2 diabetes: A common comorbidity associated with severe complications

A. J. Scheen

DIABETES & METABOLISM (2019)

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Article Gastroenterology & Hepatology

Accuracy of FibroScan Controlled Attenuation Parameter and Liver Stiffness Measurement in Assessing Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease

Peter J. Eddowes et al.

GASTROENTEROLOGY (2019)

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Review Gastroenterology & Hepatology

Diagnostic accuracy of controlled attenuation parameter (CAP) as a non-invasive test for steatosis in suspected non-alcoholic fatty liver disease: a systematic review and meta-analysis

Ke Pu et al.

BMC GASTROENTEROLOGY (2019)

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Article Gastroenterology & Hepatology

Outcomes of liver transplantation for non-alcoholic steatohepatitis: A European Liver Transplant Registry study

Debashis Haldar et al.

JOURNAL OF HEPATOLOGY (2019)

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Article Gastroenterology & Hepatology

Prospective evaluation of a primary care referral pathway for patients with non-alcoholic fatty liver disease

Ankur Srivastava et al.

JOURNAL OF HEPATOLOGY (2019)

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Review Gastroenterology & Hepatology

From NASH to HCC: current concepts and future challenges

Quentin M. Anstee et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

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Article Medicine, General & Internal

Cohort profile: the Trivandrum non-alcoholic fatty liver disease (NAFLD) cohort

Jane Chalmers et al.

BMJ OPEN (2019)

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Article Gastroenterology & Hepatology

Long-term metformin use may improve clinical outcomes in diabetic patients with non-alcoholic steatohepatitis and bridging fibrosis or compensated cirrhosis

Eduardo Vilar-Gomez et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2019)

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Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years

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Article Gastroenterology & Hepatology

Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease

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Diagnosis of Fibrosis and Cirrhosis Using Liver Stiffness Measurement in Nonalcoholic Fatty Liver Disease

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Letter Gastroenterology & Hepatology

Nonalcoholic Fatty Liver in a Developing Country is Responsible for Significant Liver Disease

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HEPATOLOGY (2010)

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Nonobese Population in a Developing Country Has a High Prevalence of Nonalcoholic Fatty Liver and Significant Liver Disease

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End-stage nonalcoholic fatty liver disease: evaluation of pathomorphologic features and relationship to cryptogenic cirrhosis from study of explant livers in a living donor liver transplant program

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Review Medicine, General & Internal

Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease

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NEW ENGLAND JOURNAL OF MEDICINE (2010)

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Review Gastroenterology & Hepatology

Liver Biopsy

Don C. Rockey et al.

HEPATOLOGY (2009)

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Article Gastroenterology & Hepatology

Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes

Anna Ludovica Fracanzani et al.

HEPATOLOGY (2008)

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Article Gastroenterology & Hepatology

The clinicopathological profile of indian patients with nonalcoholic fatty liver disease (NAFLD) is different from that in the west

Ajay Duseja et al.

DIGESTIVE DISEASES AND SCIENCES (2007)

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Article Gastroenterology & Hepatology

Prevalence of non-alcoholic fatty liver disease: population based study

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ANNALS OF HEPATOLOGY (2007)

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The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD

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Long-term follow-up of patients with NAFLD and elevated liver enzymes

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HEPATOLOGY (2006)

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Non-alcoholic fatty liver disease may not be a severe disease at presentation among Asian Indians

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WORLD JOURNAL OF GASTROENTEROLOGY (2006)

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Effect of exercise and dietary modification on serum aminotransferase levels in patients with nonalcoholic steatohepatitis

CS Baba et al.

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Review Gastroenterology & Hepatology

Review article: non-alcoholic fatty liver disease and hepatitis C - risk factors and clinical implications

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ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2005)

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Article Gastroenterology & Hepatology

Sampling variability of liver biopsy in nonalcoholic fatty liver disease

V Ratziu et al.

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Design and validation of a histological scoring system for nonalcoholic fatty liver disease

DE Kleiner et al.

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Macrovesicular hepatic steatosis in living related liver donors: Correlation between CT and histologic findings

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Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values

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The utility of radiological imaging in nonalcoholic fatty liver disease

S Saadeh et al.

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Review Medicine, General & Internal

Current concepts: Liver biopsy.

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NEW ENGLAND JOURNAL OF MEDICINE (2001)

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Indian National Association for Study of the Liver (INASL) Guidance Paper on Nomenclature, Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)

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