4.8 Article

Target-Specific 3D DNA Gatekeepers for Biomimetic Nanopores

期刊

ADVANCED MATERIALS
卷 27, 期 12, 页码 2090-2095

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201405078

关键词

biomimetics; DNA; gating; nanopores; responsive materials; smart materials

资金

  1. National Research Fund for Fundamental Key Projects [2015CB932600, 2013CB933000, 2011CB935700]
  2. National Natural Science Foundation of China [21375042, 21405054, 21103201, 11290163, 91127025]
  3. HUST
  4. Beijing Nova Program

向作者/读者索取更多资源

3D cross-linked DNA superstructures switch off the ionic flux through solidstate nanopores with extremely high ON-OFF ratios of 10(3) - 10(5). This gating mechanism can be generally applicable in a wide range of nanopores with opening diameters up to 650 nm. The 3D bio-supramolecular gatekeepers outperform previous low-dimensional or simple-structured DNA functional components.

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