Endodermal sinus tumor with pancreatic origin: A case report

Endodermal Sinus tumor is a rare malignant type of germ cell tumor (GCT). Primary endodermal sinus tumor, especially in the head of pancreas, is extremely rare. The case under consideration is of a 22 year old male who presented with pancreatic mass causing postprandial nausea and vomiting, and raised AFP levels. The biopsy of the mass revealed the endodermal sinus tumor, and the pancreatic origin was confirmed by a CT scan and a negative scrotal ultrasound. As the tumor was unresectable initially, a gastrojejunostomy was done to relieve the obstructive symptoms. Whipple procedure was performed two months after 4 cycles of BEP chemotherapy to remove the residual tumor in pancreas. It is crucial to highlight this uncommon case in order to increase sur-geons' and oncologists' knowledge of the malignant extra-gonadal GCTs diagnosis and treatment.

Automated summary

The article presents a rare case of endodermal sinus tumor occurring in the head of pancreas. The diagnosis was confirmed through CT scan and biopsy, followed by chemotherapy and surgical treatment.