期刊
HELIYON
卷 9, 期 1, 页码 -出版社
CELL PRESS
DOI: 10.1016/j.heliyon.2022.e12751
关键词
IBS; Subthreshold mental disorders; Gut-brain axis; ENS with Implicit epigenetic long-term mem-ory; Hypnotherapy
The association between irritable bowel syndrome (IBS) and psychiatric and mood disorders is more significant than previously believed. Prenatal, perinatal, postnatal, and early-age conditions play a crucial role in IBS development. Subthreshold mental disorders (SMDs) may also be a significant source of various diseases and can contribute to the development of IBS. Stress-induced implicit memories in the enteric nervous system (ENS) may be responsible for the emergence and maintenance of IBS. Hypnosis has been proven to improve the primary symptoms of IBS, reduce noncolonic symptoms, and enhance quality of life and cognitive function, possibly by accessing unconscious brain processes.
The association between irritable bowel syndrome (IBS) and psychiatric and mood disorders may be more fundamental than was previously believed. Prenatal, perinatal, postnatal, and early-age conditions can have a key role in the development of IBS. Subthreshold mental disorders (SMDs) could also be a significant source of countless diverse diseases and may be a cause of IBS development. We hypothesize that stress-induced implicit memories may persist throughout life by epigenetic processes in the enteric nervous system (ENS). These stress-induced implicit memories may play an essential role in the emergence and maintenance of IBS. In recent decades, numerous studies have proven that hypnosis can improve the primary symptoms of IBS and also reduce noncolonic symptoms such as anxiety and depression and improve quality of life and cognitive function. These significant beneficial effects of hypnosis on IBS may be because hypnosis allows access to unconscious brain processes.
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