Long noncoding RNAs (IncRNAs) influence diverse cellular processes and have been implicated in regulating stem cell properties. Now in Cell Stem Cell, Ramos et al. (2015) demonstrate that the neural-specific lncRNA Pnky regulates neuronal differentiation from neural stem cells and mediates RNA splicing through interactions with polypyrimidine tract-binding protein 1 (PTBP1).
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