Idiosyncratic biases in the perception of medical images

IntroductionRadiologists routinely make life-altering decisions. Optimizing these decisions has been an important goal for many years and has prompted a great deal of research on the basic perceptual mechanisms that underlie radiologists' decisions. Previous studies have found that there are substantial individual differences in radiologists' diagnostic performance (e.g., sensitivity) due to experience, training, or search strategies. In addition to variations in sensitivity, however, another possibility is that radiologists might have perceptual biases-systematic misperceptions of visual stimuli. Although a great deal of research has investigated radiologist sensitivity, very little has explored the presence of perceptual biases or the individual differences in these. MethodsHere, we test whether radiologists' have perceptual biases using controlled artificial and Generative Adversarial Networks-generated realistic medical images. In Experiment 1, observers adjusted the appearance of simulated tumors to match the previously shown targets. In Experiment 2, observers were shown with a mix of real and GAN-generated CT lesion images and they rated the realness of each image. ResultsWe show that every tested individual radiologist was characterized by unique and systematic perceptual biases; these perceptual biases cannot be simply explained by attentional differences, and they can be observed in different imaging modalities and task settings, suggesting that idiosyncratic biases in medical image perception may widely exist. DiscussionCharacterizing and understanding these biases could be important for many practical settings such as training, pairing readers, and career selection for radiologists. These results may have consequential implications for many other fields as well, where individual observers are the linchpins for life-altering perceptual decisions.

Automated summary

Radiologists' decisions are significantly influenced by their individual differences and perceptual biases. This study found that each radiologist has unique and systematic perceptual biases, which can be observed in different imaging modalities and task settings. Understanding and characterizing these biases is crucial for training, pairing readers, and career selection for radiologists, and may also have important implications for other fields where individual observers make life-altering perceptual decisions.