4.4 Article

Associations of improvement in laboratory tests with clinical outcomes in patients with active systemic lupus erythematosus: a multinational longitudinal cohort study

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Rheumatology

Association of Modified Systemic Lupus Erythematosus Responder Index Attainment With Long-Term Clinical Outcomes: A Five-Year Prospective Study

Kathryn Connelly et al.

Summary: In long-term follow-up of patients with systemic lupus erythematosus, attainment of a modified version of the SLE Responder Index (mSRI) predicts favorable outcomes and supports the clinical meaningfulness of SRI attainment as an SLE trial end point.

ARTHRITIS & RHEUMATOLOGY (2023)

Review Rheumatology

Measurement of specific organ domains in lupus randomized controlled trials: a scoping review

Kathryn Connelly et al.

Summary: In randomized controlled trials for systemic lupus erythematosus (SLE), musculoskeletal and mucocutaneous manifestations are predominant, and organ-specific outcome measures are commonly reported but their definitions vary.

RHEUMATOLOGY (2022)

Article Rheumatology

Clinician-reported outcome measures in lupus trials: a problem worth solving

Kathryn Connelly et al.

Summary: SLE remains a disease with high unmet clinical need, and the execution of clinical trials to determine the efficacy of new therapies is challenging due to substantial patient heterogeneity. The current clinician-reported outcome measures of treatment response have notable drawbacks, and there is a research goal to define the optimal clinical trial outcome measure for SLE.

LANCET RHEUMATOLOGY (2021)

Review Medicine, General & Internal

The Complex Role of C-Reactive Protein in Systemic Lupus Erythematosus

Helena Enocsson et al.

Summary: C-reactive protein (CRP) is a sensitive but nonspecific biomarker of inflammation, with increased levels potentially predicting cardiovascular events and playing a beneficial role in autoimmune diseases. Autoimmune conditions characterized by the Type I interferon gene signature are exceptions to the general rule that CRP levels correlate with inflammation severity.

JOURNAL OF CLINICAL MEDICINE (2021)

Article Medicine, General & Internal

Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial

Brad H. Rovin et al.

Summary: This study evaluated the efficacy and safety of voclosporin for the treatment of lupus nephritis, showing a superior complete renal response rate with voclosporin in combination with MMF and low-dose steroids compared to MMF and low-dose steroids alone. The safety profile was comparable between the two groups. This finding represents an important advancement in the treatment of patients with active lupus nephritis.

LANCET (2021)

Article Medicine, General & Internal

Trial of Anifrolumab in Active Systemic Lupus Erythematosus

Eric F. Morand et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Medicine, General & Internal

Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis

Richard Furie et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Rheumatology

Development of the Asia Pacific Lupus Collaboration cohort

Rangi Kandane-Rathnayake et al.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2019)

Article Rheumatology

Definition and initial validation of a Lupus Low Disease Activity State (LLDAS)

Kate Franklyn et al.

ANNALS OF THE RHEUMATIC DISEASES (2016)

Article Rheumatology

Novel Evidence-Based Systemic Lupus Erythematosus Responder Index

Richard A. Furie et al.

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH (2009)

Review Rheumatology

C-Reactive Protein and Systemic Lupus Erythematosus

Shilpa Gaitonde et al.

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH (2008)