4.6 Review

Efficacy and safety of endothelin receptor antagonists, phosphodiesterase type 5 Inhibitors, and prostaglandins in pediatric pulmonary arterial hypertension: A network meta-analysis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Respiratory System

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

Marc Humbert et al.

EUROPEAN RESPIRATORY JOURNAL (2023)

Review Health Care Sciences & Services

The effectiveness of AGV, Ex-PRESS, or trabeculectomy in the treatment of primary and secondary glaucoma: a systematic review and network meta-analysis

Xiwen Zhang et al.

Summary: This study compared the efficacy of Ahmed, Ex-PRESS, and trabeculectomy in glaucoma surgery. The results showed that Ex-PRESS had better outcomes in terms of intraocular pressure and complete success rate after 1 year, as well as a decrease in postoperative medication use, compared to the other two types of surgery.

ANNALS OF PALLIATIVE MEDICINE (2022)

Article Respiratory System

Parenteral Prostanoids in Pediatric Pulmonary Arterial Hypertension Start Early, Dose High, Combine

Johannes M. Douwes et al.

Summary: This study retrospectively analyzed data from 275 children with PAH and found that early initiation and higher doses of IV/SC prostanoid therapy, as well as combination with other targeted drugs, were associated with better outcomes. Transition from IV/SC prostanoid therapy to oral or inhaled therapies was found to be safe in selected patients who met specific hemodynamic criteria.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2022)

Article Pediatrics

Efficacy and Safety of IV Sildenafil in the Treatment of Newborn Infants with, or at Risk of, Persistent Pulmonary Hypertension of the Newborn (PPHN): A Multicenter, Randomized, Placebo-Controlled Trial

Christine M. Pierce et al.

Summary: The study found that adding IV sildenafil to iNO was not superior to placebo in newborn infants with PPHN or at risk of PPHN. There were no significant differences between the two groups in terms of treatment failure rates, time on iNO, or secondary endpoints.

JOURNAL OF PEDIATRICS (2021)

Article Pharmacology & Pharmacy

The Efficacy and Safety of Pulmonary Vasodilators in Pediatric Pulmonary Hypertension (PH): A Systematic Review and Meta-analysis

Tingting Shu et al.

Summary: Pulmonary vasodilators significantly decrease mortality, improve respiratory and hemodynamic parameters, and reduce mechanical ventilation duration in pediatric pulmonary hypertension patients.

FRONTIERS IN PHARMACOLOGY (2021)

Article Pharmacology & Pharmacy

Efficacy and safety of novel-targeted drugs in the treatment of pulmonary arterial hypertension: a Bayesian network meta-analysis

Wenhai Fu et al.

Summary: The study findings indicate that targeted medications show significant advantages in improving symptoms and clinical outcomes in PAH patients, but safety concerns remain, warranting cautious use.

DRUG DELIVERY (2021)

Review Medicine, General & Internal

Endothelin receptor antagonists for pulmonary arterial hypertension

Chao Liu et al.

Summary: Endothelin receptor antagonists are effective in improving exercise capacity, functional class, and cardiopulmonary variables in patients with pulmonary arterial hypertension, but may have limited effect on reducing dyspnoea and mortality. Close monitoring of liver function is necessary during treatment with ERAs. Further studies are needed to confirm the potential benefits of combined use of ERAs with phosphodiesterase inhibitors.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2021)

Review Cardiac & Cardiovascular Systems

Update on pediatric pulmonary arterial hypertension

Dunbar Ivy et al.

Summary: Pulmonary arterial hypertension (PAH) in children is associated with high morbidity and mortality. Recent advancements in diagnosis and treatment include updated definitions, FDA approval of the first targeted therapy, and improved risk stratification through advanced imaging and monitoring. New therapies have shown improved outcomes for affected children.

CURRENT OPINION IN CARDIOLOGY (2021)

Article Cardiac & Cardiovascular Systems

Prostanoids in pediatric pulmonary hypertension: clinical response, time-to-effect, and dose-response

Joseph B. Tella et al.

PULMONARY CIRCULATION (2020)

Article Respiratory System

Haemodynamic definitions and updated clinical classification of pulmonary hypertension

Gerald Simonneau et al.

EUROPEAN RESPIRATORY JOURNAL (2019)

Article Respiratory System

Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management

Erika B. Rosenzweig et al.

EUROPEAN RESPIRATORY JOURNAL (2019)

Article Pediatrics

Sildenafil Use in Children with Pulmonary Hypertension

Jennifer L. Cohen et al.

JOURNAL OF PEDIATRICS (2019)

Review Cardiac & Cardiovascular Systems

The Efficacy and Safety of Aerosolized Iloprost in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis

Hongyu Kuang et al.

AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS (2019)

Review Medicine, General & Internal

Prostacyclin for pulmonary arterial hypertension

Hayley Barnes et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2019)

Review Cardiac & Cardiovascular Systems

Pulmonary Hypertension in Infants, Children, and Young Adults

Georg Hansmann

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2017)

Review Medicine, General & Internal

Sildenafil for pulmonary hypertension in neonates

Lauren E. Kelly et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)

Article Cardiac & Cardiovascular Systems

The role of preoperative sildenafil therapy in controlling of postoperative pulmonary hypertension in children with ventricular septal defects

Hamid Bigdelian et al.

JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH (2017)

Article Cardiac & Cardiovascular Systems

The effect of intravenous iloprost on pulmonary artery hypertension after paediatric congenital heart surgery

Ismihan Selen Onan et al.

INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY (2016)

Review Medicine, General & Internal

Endothelin receptor antagonists for persistent pulmonary hypertension in term and late preterm infants

Kiran More et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2016)

Article Cardiac & Cardiovascular Systems

First experience with sildenafil after Fontan operation: short-term outcomes

Raffaele Giordano et al.

JOURNAL OF CARDIOVASCULAR MEDICINE (2015)

Review Medicine, General & Internal

Sildenafil in pediatric pulmonary arterial hypertension

A. K. Dhariwal et al.

JOURNAL OF POSTGRADUATE MEDICINE (2015)

Article Critical Care Medicine

Assessing Pulmonary Hypertensive Vascular Disease in Childhood

M. J. del Cerro Marin et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)

Article Health Care Sciences & Services

Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range

Xiang Wan et al.

BMC MEDICAL RESEARCH METHODOLOGY (2014)

Review Cardiac & Cardiovascular Systems

Efficacy and safety of sildenafil treatment in pulmonary arterial hypertension: A systematic review

Rong-chun Wang et al.

RESPIRATORY MEDICINE (2014)

Article Medicine, General & Internal

Meta-analysis of randomized controlled trials of bosentan for treatment of pulmonary arterial hypertension

Young Ho Lee et al.

KOREAN JOURNAL OF INTERNAL MEDICINE (2013)

Article Cardiac & Cardiovascular Systems

Pediatric Pulmonary Hypertension in the Netherlands Epidemiology and Characterization During the Period 1991 to 2005

Rosa Laura E. van Loon et al.

CIRCULATION (2011)

Article Respiratory System

Long-term efficacy of bosentan in treatment of pulmonary arterial hypertension in children

A. A. Hislop et al.

EUROPEAN RESPIRATORY JOURNAL (2011)

Article Medicine, General & Internal

The Cochrane Collaboration's tool for assessing risk of bias in randomised trials

Julian P. T. Higgins et al.

BMJ-BRITISH MEDICAL JOURNAL (2011)

Article Obstetrics & Gynecology

The Use of Sildenafil in Persistent Pulmonary Hypertension of the Newborn

Arturo Vargas-Origel et al.

AMERICAN JOURNAL OF PERINATOLOGY (2010)

Article Pharmacology & Pharmacy

Bosentan in Pediatric Patients with Pulmonary Arterial Hypertension

Maurice Beghetti

CURRENT VASCULAR PHARMACOLOGY (2009)

Editorial Material Medicine, General & Internal

Guidelines for the prevention of central venous catheter-related blood stream infections with prostanoid therapy for pulmonary arterial hypertension

A. K. Doran et al.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2008)

Article Critical Care Medicine

Sildenafil prevents rebound pulmonary hypertension after withdrawal of nitric oxide in children

Poongundran Namachivayam et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

Article Cardiac & Cardiovascular Systems

Response to bosentan in children with pulmonary hypertension

S Maiya et al.

Article Cardiac & Cardiovascular Systems

Effects of long-term bosentan in children with pulmonary arterial hypertension

EB Rosenzweig et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)

Article Cardiac & Cardiovascular Systems

Antiproliferative effect of sildenafil on human pulmonary artery smooth muscle cells

B Tantini et al.

BASIC RESEARCH IN CARDIOLOGY (2005)

Article Pharmacology & Pharmacy

Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension

RJ Barst et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2003)

Article Medicine, General & Internal

Inhaled iloprost for severe pulmonary hypertension

H Olschewski et al.

NEW ENGLAND JOURNAL OF MEDICINE (2002)