☆ 4.6 Review

Latest advances in biomimetic nanomaterials for diagnosis and treatment of cardiovascular disease

FRONTIERS IN CARDIOVASCULAR MEDICINE (2023)

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Article Chemistry, Multidisciplinary

M2-type exosomes nanoparticles for rheumatoid arthritis therapy via macrophage re-polarization

Hui Li et al.

Summary: The combination therapy using M2 macrophage exosomes loaded with IL-10 pDNA and BSP was effective in targeting and reducing inflammation in RA. The synergistic effects of IL-10 pDNA and BSP promoted M1-to-M2 macrophage polarization, demonstrating high anti-inflammatory activity and therapeutic effect against RA.

JOURNAL OF CONTROLLED RELEASE (2022)

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Review Cardiac & Cardiovascular Systems

Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis

Wei Chen et al.

Summary: Nanotechnology has the potential to improve our understanding of the pathophysiology of atherosclerosis and contribute to the development of novel diagnostic and therapeutic strategies. Targeted nanoparticles for macrophages offer more precise imaging and treatment methods. Future directions include accelerating the clinical translation of nanomedicine for the treatment of atherosclerosis.

NATURE REVIEWS CARDIOLOGY (2022)

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Article Chemistry, Analytical

Bimetallic Nanomaterials-Based Electrochemical Biosensor Platforms for Clinical Applications

Palanisamy Kannan et al.

Summary: Diabetes is a major global health issue causing significant deaths and suffering. The development of advanced and sensitive blood sugar detection methods is crucial for managing diabetes. Bimetallic nanoparticles have potential clinical applications in various fields, but their utilization has been limited due to concerns about stability, bio-degradability, cluster formation, chemical reactivity, and biocompatibility. This review focuses on bimetallic nanomaterial-based glucose biosensing approaches and their substantial development compared to monometallic counterparts and other nanomaterials used in clinical applications.

MICROMACHINES (2022)

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Review Oncology

Targeted Delivery Methods for Anticancer Drugs

Valery V. Veselov et al.

Summary: This article discusses the current main technological strategies for delivering anticancer drugs and introduces several drug-delivery systems that have been successfully applied in cancer therapy. Cell-targeted delivery can reduce toxicity and increase effectiveness and selectivity. Besides traditional liposomal and micellar formulations, nanocarrier systems have recently become the focus of developmental interest.

CANCERS (2022)

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Review Pharmacology & Pharmacy

Liposomal-Based Formulations: A Path from Basic Research to Temozolomide Delivery Inside Glioblastoma Tissue

Roxana-Maria Amarandi et al.

Summary: This review discusses the potential of liposomal formulations as nano-carriers to improve the therapeutic efficacy of temozolomide (TMZ) in treating glioblastoma (GBM). Liposomes have the ability to encapsulate drugs and cross the blood-brain barrier, but further research and exploration are needed.

PHARMACEUTICS (2022)

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Article Chemistry, Analytical

CTnI diagnosis in myocardial infarction using G-quadruplex selective Ir(III) complex as effective electrochemiluminescence probe

Shujie Wu et al.

Summary: In this study, strong electrochemiluminescence (ECL) emission was achieved using a G-quadruplex selective iridium (III) complex as an efficient ECL signal probe. By introducing the iridium (III) complex through its specific interaction with G-quadruplex DNA modified on the surface of negatively charged gold nanoparticles ((- )AuNPs), an increased ECL signal was induced, which allowed for quantitative detection of cTnI in a range of 5.0 fg/mL100 ng/mL with a detection limit of 1.67 fg/mL. The proposed immunosensor showed great potential in the early diagnosis of acute myocardial infarction (AMI) by successfully detecting cTnI in human serums from healthy individuals and AMI patients.

TALANTA (2022)

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Review Chemistry, Multidisciplinary

Latest Advances in Biomimetic Cell Membrane-Coated and Membrane-Derived Nanovectors for Biomedical Applications

Riccardo Rampado et al.

Summary: In recent years, biomimetic materials have emerged as an alternative design approach for the development of innovative nanovectors. These materials use cell-derived components and coatings to endow nanomaterials with biological properties and functions.

NANOMATERIALS (2022)

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Review Pharmacology & Pharmacy

Nanocarrier Drug Delivery Systems: Characterization, Limitations, Future Perspectives and Implementation of Artificial Intelligence

Samar Zuhair Alshawwa et al.

Summary: There is an increasing demand for the development of nanocarriers that can target multiple diseases with a broad range of properties. Nanocarriers, due to their tiny size, large surface area, and feasible targetability, have optimized efficacy, decreased side effects, and improved stability compared to conventional drug dosage forms. Various types of nanocarriers have been synthesized for drug delivery, and characterization techniques have been proposed and used to predict the behavior of nanocarriers in vitro and in vivo. However, challenges in safety, regulation, and manufacturing hinder the translation of nanocarriers from the laboratory to the clinic.

PHARMACEUTICS (2022)

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Article Engineering, Biomedical

Neutrophil membrane-mimicking nanodecoys with intrinsic anti-infiammatory properties alleviate sepsis-induced acute liver injury and lethality in a mouse endotoxemia model

Yao Xiao et al.

Summary: This study explores the use of neutrophil membrane-mimicking nanodecoys (NM) as a biomimetic nanomedicine for the treatment of sepsis-associated liver injury. NM administration shows excellent biocompatibility and effectively reduces inflammatory cytokines and liver injury biomarkers, reduces hepatic malondialdehyde content and myeloperoxidase activity, and improves survival in a septic mouse model. In vitro studies also demonstrate that NM neutralizes neutrophil chemokines and inflammatory mediators, and mitigates neutrophil chemotaxis and adhesion. NM also attenuates lipopolysaccharide-induced reactive oxygen species generation, cyclooxygenase-2 expression, nitric oxide secretion, and subsequent hepatocyte injury. This study provides a promising therapeutic strategy for sepsis-induced acute liver injury.

MATERIALS TODAY BIO (2022)

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Review Pharmacology & Pharmacy

Cell-based drug delivery systems and their in vivo fate

Liuxin Yang et al.

Summary: Cell-based drug delivery systems have gained attention for their unique biological properties and self-powered functions. They exhibit excellent biocompatibility, low immunogenicity, long circulation time, tissue-homing characteristics, and the ability to cross biological barriers. Various cells have been explored as functional vectors for loading and delivering therapeutic payloads, showing potential for disease treatment. The fate of these cell-based drug delivery systems in vivo depends on biological properties, loaded drugs, physiological and pathological circumstances, and the body's response.

ADVANCED DRUG DELIVERY REVIEWS (2022)

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Review Chemistry, Multidisciplinary

Noble Metal-Based Catalysts with Core-Shell Structure for Oxygen Reduction Reaction: Progress and Prospective

Chao Wang et al.

Summary: This review summarizes the recent progress in noble metal-based core-shell catalysts for oxygen reduction reactions in proton exchange membrane fuel cells. It highlights the effects of preparation methods, temperature, doping elements, and shell layers on the catalyst performance. The difficulties of mass production and high cost of these catalysts are also discussed. The review proposes research directions for the development of high-performance catalysts with simple synthesis and low cost.

NANOMATERIALS (2022)

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Review Chemistry, Medicinal

Ag2O Nanoparticles as a Candidate for Antimicrobial Compounds of the New Generation

Sergey Gudkov et al.

Summary: Antibiotic resistance is a significant issue in modern medicine, and silver oxide nanoparticles have emerged as a promising solution due to their ease of production, low cost, high antibacterial activity, and low toxicity to eukaryotic cells.

PHARMACEUTICALS (2022)

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Article Biophysics

Comparative analysis of PEG-liposomes and RBCs-derived nanovesicles for anti-tumor therapy

Supriya Mehta et al.

Summary: Liposomes and red blood cell-derived nanovesicles are two ideal drug delivery vehicles. Liposomes, conjugated with PEG, have been used in several nano-medicines on the market, while nanovesicles derived from red blood cells may not stimulate the immune system due to the presence of self-recognition markers. However, a direct comparison between the two is still lacking.

COLLOIDS AND SURFACES B-BIOINTERFACES (2022)

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Article Multidisciplinary Sciences

Photoacoustic image-guided biomimetic nanoparticles targeting rheumatoid arthritis

Jianhai Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)

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Review Virology

Virus-like Particles as Nanocarriers for Intracellular Delivery of Biomolecules and Compounds

Junyao He et al.

Summary: Virus-like particles (VLPs) are assembled nanostructures made from viral proteins, and they have been widely used for vaccine development and as nanocarriers for cargo delivery. VLPs have good cell penetrating property, making them ideal for intracellular delivery of biomolecules and drugs. This article summarizes the current advances and applications of VLPs as delivery vectors, including the delivery of different types of biomolecules and drugs, and highlights the strategies for cargo packaging. The production and applications of VLPs are briefly reviewed, along with a discussion on future challenges in this field.

VIRUSES-BASEL (2022)

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Review Medicine, Research & Experimental

Targeted delivery of nanomedicines for promoting vascular regeneration in ischemic diseases

Jie Zhuang et al.

Summary: Ischemic diseases, the leading cause of disability and death, require the regeneration of functional vasculature network for treatment. Direct delivery of pro-angiogenesis factors has obstacles. This review summarizes the molecular mechanisms of inducing vascular regeneration and introduces the delivery of nanomedicines.

THERANOSTICS (2022)

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Review Biochemistry & Molecular Biology

Noble metal nanomaterials for the diagnosis and treatment of hematological malignancies

Xin Huang et al.

Summary: This mini review focuses on the use of noble metal nanomaterials (NM NMs) in the diagnosis and treatment of hematological malignancies. NM NMs have the potential to overcome the limitations of current anti-cancer drugs and have been employed for tracking and drug delivery. The construction of effective NM NMs-dependent theranostic methodology has the potential to provide interdisciplinary knowledge for the development of clinical tracing, diagnosis, and treatment of refractory hematological diseases.

FRONTIERS IN BIOSCIENCE-LANDMARK (2022)

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Review Chemistry, Multidisciplinary

Application of targeted therapy strategies with nanomedicine delivery for atherosclerosis

Le-chun Ou et al.

Summary: Atherosclerosis is the main pathological cause of coronary heart disease, and current clinical interventions are relatively effective for early plaque but not ideal for advanced AS, resulting in high residual risk. Nanomedicine shows great potential in anti-AS therapy, with targeted nanoparticles becoming an important strategy to further reduce residual risk of cardiovascular events. Feasibility and safety of nanotechnology in clinical treatment have been preliminarily confirmed.

ACTA PHARMACOLOGICA SINICA (2021)

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Review Chemistry, Analytical

Applications of gold nanoparticles in ELISA, PCR, and immuno-PCR assays: A review

Mahdis Sadat Tabatabaei et al.

Summary: The development of advanced assays for sensitive and specific detection of disease biomarkers has attracted significant interest, with gold nanoparticles playing a crucial role in enhancing the sensitivity and specificity of traditional immunoassays.

ANALYTICA CHIMICA ACTA (2021)

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Article Chemistry, Multidisciplinary

Advances in Single-Atom Nanozymes Research†

Bing Jiang et al.

Summary: Nanozymes with intrinsic enzyme-like properties have attracted significant interest due to their potential to address the limitations of traditional enzymes, but their activity is generally lower than natural enzymes. Single-atom nanozymes (SAzymes) with well-defined electronic and geometric structures have shown promise as direct surrogates of traditional enzymes.

CHINESE JOURNAL OF CHEMISTRY (2021)

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Review Nanoscience & Nanotechnology

Gold Nanozymes: From Concept to Biomedical Applications

Javier Lou-Franco et al.

Summary: Gold nanoparticles with enzyme-mimicking activities show great potential for applications in biomedicine, but the challenge lies in controlling their physicochemical properties and minimizing side effects for in vivo applications. Specific biorecognition elements may need to be immobilized onto nanozymes to enhance their activity, requiring further research on external parameters and toxicity studies for in vivo applicability.

NANO-MICRO LETTERS (2021)

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Article Nanoscience & Nanotechnology

Noble-Metal Nanorod Cryoaerogels with Electrocatalytically Active Surface Sites

Daniel Zambo et al.

Summary: By optimizing the synthesis of noble-metal nanorods and cryoaerogels, functional macrostructures with prominent electrocatalytic activity can be constructed.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Review Chemistry, Multidisciplinary

Nanozyme Catalytic Turnover and Self-Limited Reactions

Mohamad Zandieh et al.

Summary: The article discusses the issue of calculating catalytic turnover rates of nanozymes, emphasizing that only surface atoms should be considered as active sites. Different types of nanozymes exhibit varying catalytic activity characteristics, which may be influenced by the adsorption of reaction products.

ACS NANO (2021)

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Article Chemistry, Physical

Recent advances in active targeting of nanomaterials for anticancer drug delivery

Bijaideep Dutta et al.

Summary: The use of nanomaterials in cancer therapy has the potential to significantly impact drug delivery by enhancing drug concentration at tumor sites, improving drug content in formulations, and increasing colloidal stability. Nanocarriers with tumor-specific moieties can target cancer cells with high affinity and accuracy, overcoming issues such as aimless drug biodistribution and undesired toxicity. Active drug targeting through nanocarriers is a promising strategy for improving cancer management.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2021)

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Article Engineering, Biomedical

Clinical progress and advanced research of red blood cells based drug delivery system

Yichen Li et al.

Summary: Red blood cells have been utilized as biocompatible carriers for delivering bioactive substances for many years, with some drug-loaded RBC formulations reaching clinical trials for treating tumors and neurological diseases. Advanced delivery strategies have been proposed by combining RBCs with other novel systems to further exploit and expand the application of RBCs.

BIOMATERIALS (2021)

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Review Biotechnology & Applied Microbiology

Plant Exosome-like Nanovesicles: Emerging Therapeutics and Drug Delivery Nanoplatforms

Haseeb Anwar Dad et al.

Summary: Plant exosome-like nanovesicles, rich in bioactive components, hold great potential in the fields of biotreatment and drug delivery, exhibiting immunomodulatory, antitumor, regenerative, and anti-inflammatory effects. Their physicochemical traits make them promising candidates for next-generation therapeutic and drug delivery nanoplatforms.

MOLECULAR THERAPY (2021)

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Review Pharmacology & Pharmacy

Evolution of blood-brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies

Liang Han et al.

Summary: This review focuses on nanoscale brain-targeting drug delivery strategies designed based on blood-brain barrier (BBB) alterations and their applications in various brain diseases. However, advances on optimization of small molecules for BBB crossing and non-systemic administration routes such as intranasal treatment are not included in this review.

ACTA PHARMACEUTICA SINICA B (2021)

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Review Engineering, Biomedical

Nanozyme-based medicine for enzymatic therapy: progress and challenges

Qian Wang et al.

Summary: Nanozymes are nanomaterials with enzyme-like characteristics that can overcome the limitations of natural enzymes in enzymatic therapy. They have various activities that can either protect cells or kill harmful cells, showing great potential in medical applications.

BIOMEDICAL MATERIALS (2021)

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Article Biophysics

AuPeroxidase nanozymes: Promises and applications in biosensing

Bankuru Navyatha et al.

Summary: Gold nanozymes, with intrinsic catalytic activity, have emerged as a promising alternative to natural enzymes due to their ease of synthesis, surface modifications, stability, and excellent peroxidase activity. Their use in biosensing applications has seen a significant increase in recent years, with a focus on assessing peroxidase activity and detection of various analytes. Researchers have also explored the mechanisms behind the intrinsic peroxidase activity in gold nanozymes.

BIOSENSORS & BIOELECTRONICS (2021)

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Review Cardiac & Cardiovascular Systems

Acute Myocardial Infarction Biosensor: A Review From Bottom Up

J. A. Reyes-Retana et al.

Summary: Acute myocardial infarction is a cardiovascular disease caused by a deficiency of oxygen leading to irreversible damage to the heart muscle. In addition to electrocardiogram investigation, measuring levels of biomarkers in plasma or saliva has become a commonly applied strategy for predicting the prognosis of AMI. Researchers worldwide are developing various biosensors to enhance detection, utilizing different materials and configurations to enable different types of detection.

CURRENT PROBLEMS IN CARDIOLOGY (2021)

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Article Chemistry, Multidisciplinary

TiO2 supported single Ag atoms nanozyme for elimination of SARS-CoV2

Daji Wang et al.

Summary: The outbreak of SARS-coronavirus 2 has become a global health emergency, with no effective treatment available. A TiO2 supported single-atom nanozyme containing atomically dispersed Ag atoms, Ag-TiO2 SAN, has high adsorption of SARS-CoV2 pseudovirus and shows promising antiviral effects.

NANO TODAY (2021)

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Correction Cardiac & Cardiovascular Systems

Reappraising the role of inflammation in heart failure (vol 17, pg 269, 2020)

Luigi Adamo et al.

NATURE REVIEWS CARDIOLOGY (2021)

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Review Biotechnology & Applied Microbiology

Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

Saghi Nooraei et al.

Summary: Virus-like particles (VLPs) are virus-derived structures without genetic material, able to self-assemble and mimic viruses, utilized in candidate vaccines and successful applications in targeted drug delivery and gene therapy. Modifying the surface of VLPs for increased specificity and longevity in specific cells or tissues may enhance their future use.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

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Review Chemistry, Physical

ROS-Based Nanoparticles for Atherosclerosis Treatment

Xin Hu et al.

Summary: Atherosclerosis is the leading cause of death in western developed countries, and early prevention and effective treatment are crucial. Nanoparticles with unique characteristics offer new options for AS treatment, especially through ROS-based NPs for targeted therapy, prolonged effects, and reduced side effects.

MATERIALS (2021)

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Review Chemistry, Multidisciplinary

Surface loading of nanoparticles on engineered or natural erythrocytes for prolonged circulation time: strategies and applications

Si-qi Zhang et al.

Summary: Nano drug-delivery systems can enhance drug efficiency and reduce toxicity, and prolonging the circulation time of nanoparticles by loading them onto erythrocytes shows great potential. However, the key lies in properly attaching nanoparticles to erythrocytes for optimal results in drug delivery systems.

ACTA PHARMACOLOGICA SINICA (2021)

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Review Pharmacology & Pharmacy

Cancer treatment-related cardiovascular disease: Current status and future research priorities

Miki Nonaka et al.

Summary: Advances in cancer treatment have improved outcomes and led to an increase in cancer survivors, but also raise concerns about cardiovascular complications. It is important to consider both the prognosis and quality of life of cancer patients, and to take measures to prevent and treat cancer treatment-related cardiovascular diseases.

BIOCHEMICAL PHARMACOLOGY (2021)

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Article Engineering, Biomedical

Tumor cell membrane-based peptide delivery system targeting the tumor microenvironment for cancer immunotherapy and diagnosis

Xiangzhou Meng et al.

Summary: A multifunctional delivery system (SPIO NP@M) was developed for delivering therapeutic peptides into the tumor microenvironment effectively. The system aggregated at tumor sites for imaging, extended peptide half-life, and inhibited tumor growth both in vitro and in vivo, making it a promising platform for tumor diagnosis and treatment.

ACTA BIOMATERIALIA (2021)

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Article Multidisciplinary Sciences

Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery

Michael Segel et al.

Summary: Eukaryotic genomes contain domesticated genes from integrating viruses and mobile genetic elements, including mammalian Gag homologs and PEG10, which can be used for RNA delivery. The development of selective endogenous encapsidation for cellular delivery (SEND) using PEG10 demonstrates its potential as an efficient therapeutic delivery modality.

SCIENCE (2021)

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Review Biochemistry & Molecular Biology

Mitochondrial Redox Signaling and Oxidative Stress in Kidney Diseases

Ana Karina Aranda-Rivera et al.

Summary: Mitochondria play essential roles in cell physiology and kidney diseases by generating cellular energy and producing reactive oxygen species (ROS). However, overproduction of ROS in kidney diseases can lead to oxidative stress, disrupting mitochondrial function and altering cell signaling pathways, ultimately causing inflammation and cell apoptosis. Studies on the dysregulation of redox-sensitive signaling pathways in mitochondria could provide insights into potential therapeutic targets for kidney diseases.

BIOMOLECULES (2021)

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Review Engineering, Biomedical

Platinum group element-based nanozymes for biomedical applications: an overview

Shao-Bin He et al.

Summary: With the development of platinum group element-based nanozymes, the application of nanozymes in the field of biomedicine has been expanded, possessing high catalytic efficiency and stability, suitable for applications in bio-detection, biomedical imaging, and other fields. The focus of the research is to reveal their roles and overcome limitations in biomedical applications, and trends and prospects for the future are also provided.

BIOMEDICAL MATERIALS (2021)

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Article Medicine, Research & Experimental

Macrophage membrane functionalized biomimetic nanoparticles for targeted anti-atherosclerosis applications

Yi Wang et al.

Summary: This study aimed to develop an ideal biomimetic nanoparticle for targeted atherosclerosis (AS) therapy. The results showed that the advanced MM/RAPNPs demonstrated good biocompatibility, effectively inhibited the progression of AS, and displayed favorable safety performance in AS mouse models. These biomimetic nanoparticles may be potential drug delivery systems for safe and effective anti-AS applications.

THERANOSTICS (2021)

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Review Chemistry, Multidisciplinary

When Nanozymes Meet Single-Atom Catalysis

Lei Jiao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

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Article Cardiac & Cardiovascular Systems

Rapamycin-Loaded Biomimetic Nanoparticles Reverse Vascular Inflammation

Christian Boada et al.

CIRCULATION RESEARCH (2020)

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Review Chemistry, Physical

Antioxidant properties of gold nanozyme: A review

Majid Sharifi et al.

JOURNAL OF MOLECULAR LIQUIDS (2020)

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Review Chemistry, Analytical

The synthesis of metal nanoclusters and their applications in bio-sensing and imaging

Yu Zhao et al.

METHODS AND APPLICATIONS IN FLUORESCENCE (2020)

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Article Chemistry, Multidisciplinary

Engineered Nanoplatelets for Targeted Delivery of Plasminogen Activators to Reverse Thrombus in Multiple Mouse Thrombosis Models

Junchao Xu et al.

ADVANCED MATERIALS (2020)

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Review Chemistry, Multidisciplinary

Catalytically Active Peptide-Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes

Dorian J. Mikolajczak et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

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Article Obstetrics & Gynecology

Two phase 3, double-blind, placebo-controlled studies of the efficacy and safety of Astodrimer 1% Gel for the treatment of bacterial vaginosis

Steven E. Chavoustie et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2020)

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Correction Chemistry, Multidisciplinary

Copper/Carbon Hybrid Nanozyme: Tuning Catalytic Activity by the Copper State for Antibacterial Therapy (vol 19, pg 7645, 2019)

Juqun Xi et al.

NANO LETTERS (2020)

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Review Cardiac & Cardiovascular Systems

Neutrophils as regulators of cardiovascular inflammation

Carlos Silvestre-Roig et al.

NATURE REVIEWS CARDIOLOGY (2020)

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Review Pharmacology & Pharmacy

Extracellular vesicles as drug delivery systems: Why and how?

Omnia M. Elsharkasy et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

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Article Multidisciplinary Sciences

Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

Cheng Gao et al.

NATURE COMMUNICATIONS (2020)

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Review Immunology

Nanoparticle Platforms for Antigen-Specific Immune Tolerance

Edward B. Thorp et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Article Chemistry, Analytical

A heparin-modified palladium nanozyme for photometric determination of protamine

Qingwei Huang et al.

MICROCHIMICA ACTA (2020)

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Article Chemistry, Multidisciplinary

Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic

Carsten Weiss et al.

ACS NANO (2020)

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Review Cardiac & Cardiovascular Systems

A link between inflammation and thrombosis in atherosclerotic cardiovascular diseases: Clinical and therapeutic implications

Evangelos Oikonomou et al.

ATHEROSCLEROSIS (2020)

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Review Biochemistry & Molecular Biology

Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

Heiko Bugger et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2020)

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Review Cardiac & Cardiovascular Systems

Advanced Heart Failure Epidemiology, Diagnosis, and Therapeutic Approaches

Lauren K. Truby et al.

JACC-HEART FAILURE (2020)

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Article Nanoscience & Nanotechnology

Intrinsic Peroxidase-Mimicking Ir Nanoplates for Nanozymatic Anticancer and Antibacterial Treatment

Gyeonghye Yim et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Nanoscience & Nanotechnology

Heart Valves Cross-Linked with Erythrocyte Membrane Drug-Loaded Nanoparticles as a Biomimetic Strategy for Anti-coagulation, Anti-inflammation, Anti-calcification, and Endothelialization

Cheng Hu et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

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Article Chemistry, Multidisciplinary

Mitochondria-Inspired Nanoparticles with Microenvironment-Adapting Capacities for On-Demand Drug Delivery after lschemic Injury

Yanxia Lin et al.

ACS NANO (2020)

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Article Chemistry, Multidisciplinary

Cellular Nanosponges Inhibit SARS-CoV-2 Infectivity

Qiangzhe Zhang et al.

NANO LETTERS (2020)

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Review Cell Biology

Mitochondria in skin health, aging, and disease

Annapoorna Sreedhar et al.

CELL DEATH & DISEASE (2020)

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Review Cell Biology

The COVID-19 pandemic: a global health crisis

Casey A. Pollard et al.

PHYSIOLOGICAL GENOMICS (2020)

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Article Chemistry, Multidisciplinary

被撤回的出版物: Red Blood Cell Membrane-Coated Silica Nanoparticles Codelivering DOX and ICG for Effective Lung Cancer Therapy (Retracted article. See vol. 6, pg. 20088, 2021)

Jia Xiao et al.

ACS OMEGA (2020)

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Article Biotechnology & Applied Microbiology

Erythrocyte membrane coated nanoparticle-based control releasing hydrogen sulfide system protects ischemic myocardium

Kai Huang et al.

Summary: The study successfully constructed a long circulatory and sustained releasing H2S nanosystem, demonstrating its protective effects on myocardial ischemia and reperfusion injury. The system exhibited superior therapeutic effects through mechanisms including anti-apoptosis, anti-inflammatory, and antioxidant activities, providing a potential new platform for utilizing the protective effects of H2S.

NANOMEDICINE (2020)

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Review Chemistry, Multidisciplinary

Immune cells as tumor drug delivery vehicles

Francis Combes et al.

JOURNAL OF CONTROLLED RELEASE (2020)

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Review Engineering, Biomedical

Synthesis of silver nanoparticles utilizing various biological systems: mechanisms and applications-a review

Divyanshi Garg et al.

PROGRESS IN BIOMATERIALS (2020)

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Review Materials Science, Biomaterials

Cell membrane biomimetic nanoparticles for inflammation and cancer targeting in drug delivery

Huaiji Wang et al.

BIOMATERIALS SCIENCE (2020)

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Review Oncology

Cell-mediated and cell membrane-coated nanoparticles for drug delivery and cancer therapy

Serkan Yaman et al.

CANCER DRUG RESISTANCE (2020)

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Review Biochemistry & Molecular Biology

Reactive oxygen species, aging and articular cartilage homeostasis

Jesalyn A. Bolduc et al.

FREE RADICAL BIOLOGY AND MEDICINE (2019)

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Article Nanoscience & Nanotechnology

Platelet membrane-coated nanoparticle-mediated targeting delivery of Rapamycin blocks atherosclerotic plaque development and stabilizes plaque in apolipoprotein E-deficient (ApoE(-/-)) mice

Yanan Song et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2019)

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Article Chemistry, Multidisciplinary

Unveiling the Intrinsic Catalytic Activities of Single-Gold-Nanoparticle-Based Enzyme Mimetics

Mahmoud Elsayed Hafez et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

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Review Chemistry, Analytical

Direct Electrochemical Detection of Glutamate, Acetylcholine, Choline, and Adenosine Using Non-Enzymatic Electrodes

Arash Shadlaghani et al.

SENSORS (2019)

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Review Chemistry, Multidisciplinary

Peroxidase-Like Activity of Smart Nanomaterials and Their Advanced Application in Colorimetric Glucose Biosensors

Xigui Liu et al.

SMALL (2019)

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Review Pharmacology & Pharmacy

Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application

Qing Xia et al.

ACTA PHARMACEUTICA SINICA B (2019)

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Article Chemistry, Multidisciplinary

Ligand-Modified Cell Membrane Enables the Targeted Delivery of Drug Nanocrystals to Glioma

Zhilan Chai et al.

ACS NANO (2019)

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Ru(III)-Based Metal-Organic Gels: Intrinsic Horseradish and NADH Peroxidase-Mimicking Nanozyme

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Exosomes Engineered to Express a Cardiomyocyte Binding Peptide Demonstrate Improved Cardiac Retention in Vivo

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Renal clearable catalytic gold nanoclusters for in vivo disease monitoring

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Renal clearable nanochelators for iron overload therapy

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Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury

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Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins

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Rational Design of Au@Pt Multibranched Nanostructures as Bifunctional Nanozymes

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Liposome-chaperoned cell-free synthesis for the design of proteoliposomes: Implications for therapeutic delivery

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ACTA BIOMATERIALIA (2018)

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Synthesis of Pt Hollow Nanodendrites with Enhanced Peroxidase-Like Activity against Bacterial Infections: Implication for Wound Healing

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ACTA PHARMACEUTICA SINICA B (2018)

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Nanoparticle Functionalization with Platelet Membrane Enables Multifactored Biological Targeting and Detection of Atherosclerosis

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Composition-Graded PdxNi1-x Nanospheres with Pt Monolayer Shells as High-Performance Electrocatalysts for Oxygen Reduction Reaction

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Three-in-One: Sensing, Self-Assembly, and Cascade Catalysis of Cyclodextrin Modified Gold Nanoparticles

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Self-enhanced N-(aminobutyl)-N-(ethylisoluminol) derivative-based electrochemiluminescence immunosensor for sensitive laminin detection using PdIr cubes as a mimic peroxidase

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Label-free colorimetric sensor for mercury(II) and DNA on the basis of mercury(II) switched-on the oxidase-mimicking activity of silver nanoclusters

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CLINICAL IMMUNOLOGY (2015)

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CURRENT DRUG TARGETS (2015)

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Colorimetric Quantification of Glucose and Cholesterol in Human Blood Using a Nanocomposite Entrapping Magnetic Nanoparticles and Oxidases

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Mechanisms of Oxidase and Superoxide Dismutation-like Activities of Gold, Silver, Platinum, and Palladium, and Their Alloys: A General Way to the Activation of Molecular Oxygen

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Targeted gold-coated iron oxide nanoparticles for CD163 detection in atherosclerosis by MRI

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Efficient Encapsulation of Fe3O4 Nanoparticles into Genetically Engineered Hepatitis B Core Virus-Like Particles Through a Specific Interaction for Potential Bioapplications

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Graphene Quantum Dots-Band-Aids Used for Wound Disinfection

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DNA-Based Platinum Nanozymes for Peroxidase Mimetics

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PdO Doping Tunes Band-Gap Energy Levels as Well as Oxidative Stress Responses to a Co3O4 p-Type Semiconductor in Cells and the Lung

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

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Nanoparticle Drug-and Gene-eluting Stents for the Prevention and Treatment of Coronary Restenosis

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THERANOSTICS (2014)

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Liposomal drug delivery systems: From concept to clinical applications

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Sandwich-type immunosensors and immunoassays exploiting nanostructure labels: A review

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Intrinsic catalytic activity of Au nanoparticles with respect to hydrogen peroxide decomposition and superoxide scavenging

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Molecularly stabilised ultrasmall gold nanoparticles: synthesis, characterization and bioactivity

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NANOSCALE (2013)

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Noble Metal Nanoparticles for Biosensing Applications

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Direct evidence for catalase and peroxidase activities of ferritin-platinum nanoparticles

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TNF alpha in myocardial ischemia/reperfusion, remodeling and heart failure

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Organ transplantation and autoimmunity: Common mechanisms common therapies

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SEMINARS IN IMMUNOLOGY (2011)

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Self-Catalyzed, Self-Limiting Growth of Glucose Oxidase-Mimicking Gold Nanoparticles

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Positively-charged gold nanoparticles as peroxidiase mimic and their application in hydrogen peroxide and glucose detection

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CHEMICAL COMMUNICATIONS (2010)

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Design of AgM Bimetallic Alloy Nanostructures (M = Au, Pd, Pt) with Tunable Morphology and Peroxidase-Like Activity

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CHEMISTRY OF MATERIALS (2010)

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Reducing Stress on Cells with Apoferritin-Encapsulated Platinum Nanoparticles

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NANO LETTERS (2010)

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Impact of Nanotechnology on Drug Delivery

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Modulation of intracellular ROS levels by TIGAR controls autophagy

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EMBO JOURNAL (2009)

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Fabrication of Anti-human Cardiac Troponin I Immunogold Nanorods for Sensing Acute Myocardial Damage

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NANOSCALE RESEARCH LETTERS (2009)

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NATURE BIOTECHNOLOGY (2007)

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Intrinsic peroxidase-like activity of ferromagnetic nanoparticles

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NATURE NANOTECHNOLOGY (2007)

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Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity

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JOURNAL OF PHYSIOLOGY-LONDON (2007)

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Platinum nanoparticle is a useful scavenger of superoxide anion and hydrogen peroxide

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FREE RADICAL RESEARCH (2007)

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The catalytic activity of Naked gold particles

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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)

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