4.7 Article

Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

Yasset Perez-Riverol et al.

Summary: PRIDE is the largest data repository of mass spectrometry-based proteomics data in the world, with around 500 datasets submitted per month. In addition to continuous improvements in data pipelines and infrastructure, PRIDE has developed the Spectra Archive and MAGE-TAB file format to enhance sample metadata annotation and access to mass spectra.

NUCLEIC ACIDS RESEARCH (2022)

Article Neurosciences

Structural Brain Changes and Associated Symptoms of ADHD Subtypes in Children

ShuHua Mu et al.

Summary: Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous disorder with different profiles in clinical symptoms, cognitive functions, and brain structures among different subtypes. The inattentive and combined subtypes of ADHD show distinct cognitive impairments and have different subcortical brain structural changes. These findings support the heterogeneity in ADHD subtypes and the existence of brain structural differences.

CEREBRAL CORTEX (2022)

Article Clinical Neurology

Regulation of clock and clock-controlled genes during morphine reward and reinforcement: Involvement of the period 2 circadian clock

Raly James Perez Custodio et al.

Summary: The study shows that modifying the Per2 gene in mouse models can enhance the rewarding and reinforcing effects of morphine. Deletion of the Per2 gene increases the effects of morphine, while its overexpression weakens these effects.

JOURNAL OF PSYCHOPHARMACOLOGY (2022)

Article Genetics & Heredity

A Systematic Screening of ADHD-Susceptible Variants From 25 Chinese Parents-Offspring Trios

Qianqian Li et al.

Summary: The study analyzed variations in the genes of children with ADHD, identifying specific variants that might impair protein functions or gene expression regulation in ADHD children. These findings may contribute to the clinical understanding, prediction, prevention, and treatment of ADHD.

FRONTIERS IN GENETICS (2022)

Article Biochemistry & Molecular Biology

Shati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic neuronal dysfunction in the dentate gyrus

Bolati Wulaer et al.

Summary: Deficiency of Shati/Nat8l affects neurogenesis and attentional behavior in mice, possibly through modulation of dopaminergic transmission.

JOURNAL OF NEUROCHEMISTRY (2021)

Review Clinical Neurology

Wnt/β-Catenin Signaling in Neural Stem Cell Homeostasis and Neurological Diseases

Juanmei Gao et al.

Summary: The Wnt/beta-catenin signaling pathway plays a crucial role in regulating the balance of neural stem/progenitor cells (NSCs) proliferation and differentiation, which is essential for the development and maintenance of the nervous system. Recent findings suggest that components of the Wnt/beta-catenin signaling pathway are involved in the regulation of functional brain circuits, providing potential therapeutic targets for neurological diseases.

NEUROSCIENTIST (2021)

Article Biology

Low striatal T3 is implicated in inattention and memory impairment in an ADHD mouse model overexpressing thyroid hormone-responsive protein

Raly James Perez Custodio et al.

Summary: This study demonstrates that reduced levels of striatal triiodothyronine (T3) due to overexpression of thyroid hormone-responsive protein in mice can lead to inattention and memory impairment, suggesting a potential pathogenetic mechanism for ADHD. The overexpression of thyroid hormone-responsive protein in male mice replicates behavioral features of ADHD, which can serve as an animal model for the predominantly inattentive subtype of ADHD. Furthermore, TH replacement therapy in these mice rescued the inattention and memory impairment, supporting the involvement of the upregulated thyroid hormone-responsive protein gene in ADHD pathology.

COMMUNICATIONS BIOLOGY (2021)

Article Biochemistry & Molecular Biology

The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets

Damian Szklarczyk et al.

Summary: The STRING database integrates various associations between proteins, including physical interactions and functional associations, by collecting evidence from sources such as literature, databases, computational predictions, and systematic transfers. STRING aims for wide coverage and provides extensive user interface features and querying methods for experimental data.

NUCLEIC ACIDS RESEARCH (2021)

Review Behavioral Sciences

The Continuity of Context: A Role for the Hippocampus

Andrew P. Maurer et al.

Summary: The passage discusses the importance of tracking moment-to-moment change in input and detecting change sufficient to require altering behavior for survival. It focuses on how the brain evaluates change over time, with a special emphasis on the role of the hippocampus in tracking context and updating an organism's sense of its surroundings. The role of place cells in tracking contextual continuities and discontinuities is highlighted, showcasing the critical role of the hippocampus in spatial cognition and episodic memory.

TRENDS IN COGNITIVE SCIENCES (2021)

Review Public, Environmental & Occupational Health

The prevalence of adult attention-deficit hyperactivity disorder: A global systematic review and meta-analysis

Peige Song et al.

Summary: This study provides an up-to-date estimation of the global prevalence of both persistent and symptomatic adult ADHD, showing that the prevalence decreases with advancing age. Large-scale investigations and a well-defined strategy for diagnosing adult ADHD are needed.

JOURNAL OF GLOBAL HEALTH (2021)

Article Medicine, General & Internal

Identification of Brain Regions with Enhanced Functional Connectivity with the Cerebellum Region in Children with Attention Deficit Hyperactivity Disorder: A Resting-State fMRI Study

Li Ding et al.

Summary: Children with ADHD demonstrate higher functional connectivity between specific brain regions and the cerebellum, and exhibit abnormalities in cognitive function. Results from CPT show that ADHD children have significantly more omission errors and commissions compared to TD group, with no significant difference in correct reaction time between the two groups.

INTERNATIONAL JOURNAL OF GENERAL MEDICINE (2021)

Article Endocrinology & Metabolism

Developmental effects of environmental enrichment on selective and auditory sustained attention

Anna Korkhin et al.

PSYCHONEUROENDOCRINOLOGY (2020)

Review Psychiatry

Genetics of ADHD: What Should the Clinician Know?

Oliver Grimm et al.

CURRENT PSYCHIATRY REPORTS (2020)

Article Clinical Neurology

Two newly-emerging substituted phenethylamines MAL and BOD induce differential psychopharmacological effects in rodents

Raly James Perez Custodio et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2020)

Review Cell Biology

Role of Wnt Signaling in Adult Hippocampal Neurogenesis in Health and Disease

Sebastian B. Arredondo et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Genetics of attention deficit hyperactivity disorder

Stephen V. Faraone et al.

MOLECULAR PSYCHIATRY (2019)

Review Neurosciences

A Review of Heterogeneity in Attention Deficit/Hyperactivity Disorder (ADHD)

Yuyang Luo et al.

FRONTIERS IN HUMAN NEUROSCIENCE (2019)

Review Neurosciences

Recalibrating the Relevance of Adult Neurogenesis

Jason S. Snyder

TRENDS IN NEUROSCIENCES (2019)

Article Agriculture, Dairy & Animal Science

The 3Rs and Humane Experimental Technique: Implementing Change

Robert C. Hubrecht et al.

ANIMALS (2019)

Article Genetics & Heredity

The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis

Edna Gruenblatt et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2019)

Article Psychology

Sex and Gender in Psychopathology: DSM-5 and Beyond

Cynthia M. Hartung et al.

PSYCHOLOGICAL BULLETIN (2019)

Article Psychology, Experimental

Exercise modulates the interaction between cognition and anxiety in humans

Tiffany R. Lago et al.

COGNITION & EMOTION (2019)

Review Cell & Tissue Engineering

Human Adult Neurogenesis: Evidence and Remaining Questions

Gerd Kempermann et al.

CELL STEM CELL (2018)

Article Multidisciplinary Sciences

Striatal transcriptome of a mouse model of ADHD reveals a pattern of synaptic remodeling

Anastasia M. Sorokina et al.

PLOS ONE (2018)

Review Cell Biology

Review: adult neurogenesis contributes to hippocampal plasticity

Tomohisa Toda et al.

CELL AND TISSUE RESEARCH (2018)

Article Multidisciplinary Sciences

In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains

Ambika Krishnankutty et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

Evaluation of the Abuse Potential of Novel Amphetamine Derivatives with Modifications on the Amine (NBNA) and Phenyl (EDA, PMEA, 2-APN) Sites

Raly James Perez Custodio et al.

BIOMOLECULES & THERAPEUTICS (2017)

Review Developmental Biology

The thyroid hormone nuclear receptors and the Wnt/β-catenin pathway: An intriguing liaison

Seham Skah et al.

DEVELOPMENTAL BIOLOGY (2017)

Article Genetics & Heredity

Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach

Michael A. Mooney et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2016)

Article Neurosciences

Altered cholesterol biosynthesis causes precocious neurogenesis in the developing mouse forebrain

Ashley M. Driver et al.

NEUROBIOLOGY OF DISEASE (2016)

Article Multidisciplinary Sciences

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

John P. Dougherty et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2016)

Review Neurosciences

Proliferation control in neural stem and progenitor cells

Catarina C. F. Homem et al.

NATURE REVIEWS NEUROSCIENCE (2015)

Article Behavioral Sciences

Age-dependent effects of environmental enrichment on spatial memory and neurochemistry

Andrea Mora-Gallegos et al.

NEUROBIOLOGY OF LEARNING AND MEMORY (2015)

Article Developmental Biology

Adult neurogenesis: mechanisms and functional significance

Simon M. G. Braun et al.

DEVELOPMENT (2014)

Article Multidisciplinary Sciences

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

Marlen Knobloch et al.

NATURE (2013)

Review Neurosciences

WNT signaling in neuronal maturation and synaptogenesis

Silvana B. Rosso et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2013)

Article Cell Biology

The beta-Catenin Destruction Complex

Jennifer L. Stamos et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Clinical Neurology

Synaptic Wnt signaling-a contributor to major psychiatric disorders?

Nathan D. Okerlund et al.

JOURNAL OF NEURODEVELOPMENTAL DISORDERS (2011)

Article Biochemistry & Molecular Biology

Wnt signal transduction pathways

Yuko Komiya et al.

Organogenesis (2010)

Review Cell Biology

Wnt signaling pathways meet Rho GTPases

Karni Schlessinger et al.

GENES & DEVELOPMENT (2009)

Review Psychology, Developmental

ADHD in Adults A Review of the Literature

Megan A. Davidson

JOURNAL OF ATTENTION DISORDERS (2008)

Article Biochemistry & Molecular Biology

Adult neural stem cell cycling in vivo requires thyroid hormone and its alpha receptor

GF Lemkine et al.

FASEB JOURNAL (2005)

Review Cell Biology

Wnt signaling in disease and in development

R Nusse

CELL RESEARCH (2005)