☆ 4.6 Article

Gold Nanoparticles Encapsulated Resveratrol as an Anti-Aging Agent to Delay Cataract Development

PHARMACEUTICALS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Ophthalmology

Initial experiences of cataract & lens surgery in 1269 patients in outpatient clean rooms using a portable laminar air flow device

Radhika Pooja Patel et al.

Summary: In response to the COVID-19 pandemic, routine cataract surgery was halted and theatre space was limited. To address this challenge, the study developed a safe cataract pathway in outpatient department clean rooms using a sterile laminar air flow device. The initial experiences of restarting elective cataract surgery in the UK outpatient setting were positive, with no post-operative infections and high patient satisfaction.

EYE (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Resveratrol suppresses lung cancer by targeting cancer stem-like cells and regulating tumor microenvironment

Chunfeng Xie et al.

Summary: Increasing evidence suggests that cancer stem cells (CSCs) play a crucial role in tumor initiation and recurrence. Targeting CSCs and the tumor microenvironment (TME) is a novel anti-cancer approach. Resveratrol (RES) inhibits lung cancer by targeting lung cancer stem-like cells (LCSCs) and IL-6 in the TME.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2023)

添加到收藏夹

Article Chemistry, Medicinal

Hepatic-Targeted Nano-enzyme with Resveratrol Loading for Precise Relief of Nonalcoholic Steatohepatitis

Yili Tong et al.

Summary: In this study, liver-targeted Ce-based hollow mesoporous nanocarriers loaded with bioactive drugs were successfully constructed. The nanosystem enhanced cellular drug uptake and effectively treated nonalcoholic steatohepatitis, resulting in the recovery of liver function.

CHEMMEDCHEM (2023)

添加到收藏夹

Article Materials Science, Multidisciplinary

Biomimetic synthesis and characterisation of homogenouse gold nanoparticles and estimation of its cytotoxity against breast cancer cell line

Kourosh Shakerimanesh et al.

Summary: In this study, spherical gold nanoparticles were successfully synthesized using the water extract of Haplophyllum Obtusifolium. The physicochemical characteristics of the nanoparticles were determined and their effectiveness against mouse breast cancer cells was evaluated. The results showed that the nanoparticles had a spherical morphology with an average size of 12 nm. The aggregation of the particles was found to be in accordance with expectations. Furthermore, the nanoparticles exhibited lower toxicity against NIH3T3 cell lines.

MATERIALS TECHNOLOGY (2022)

添加到收藏夹

Article Immunology

ROS and DNA repair in spontaneous versus agonist-induced NETosis: Context matters

Dhia Azzouz et al.

Summary: Reactive oxygen species (ROS) play a crucial role in neutrophil extracellular trap formation. Recent studies have revealed that agonists inducing NETosis stimulate specific kinase activation and genome-wide transcription, while excess ROS generated by NADPH oxidase activating agonists lead to genome-wide DNA damage. DNA repair proteins are necessary for decondensation of chromatin in these cells. Inhibiting early steps of oxidative DNA damage repair proteins suppresses spontaneous NETosis, while inhibiting late-stage repair proteins promotes baseline NETosis. These findings highlight the differential regulation of spontaneous and agonist-induced NETosis by ROS, oxidative DNA damage, transcription, and DNA repair.

FRONTIERS IN IMMUNOLOGY (2022)

添加到收藏夹

Article Cell Biology

Biliverdin Reductase A Protects Lens Epithelial Cells against Oxidative Damage and Cellular Senescence in Age-Related Cataract

Yang Huang et al.

Summary: Age-related cataract (ARC) is a common cause of blindness worldwide, and it is associated with the accumulation of reactive oxygen species (ROS) and induction of lens epithelial cell (LEC) senescence. Biliverdin reductase A (BVRA) is capable of converting biliverdin into bilirubin, thus having the ability to scavenge ROS and protect LECs against oxidative stress through various mechanisms. However, in age-related cataract, the expression of BVRA and concentration of bilirubin are decreased, leading to a diminished antioxidative effect.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment

Ziting Zhang et al.

Summary: This study demonstrated for the first time that Resveratrol could inhibit the growth of colon cancer cells through the ROS-dependent ferroptosis pathway and promote ferroptosis by downregulating specific proteins. Biomimetic nanocarriers were developed to improve the delivery efficiency of Resveratrol for colorectal cancer treatment.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Resveratrol-Mediated Gold-Nanoceria Synthesis as Green Nanomedicine for Phytotherapy of Hepatocellular Carcinoma

Adel Ghorani-Azam et al.

Summary: In this study, CeO2@Au core-shell nanoparticles were successfully synthesized and exhibited significant cellular toxicity against liver cancerous cells. The particles ranged in size from 20nm to 170nm and could potentially be utilized in hepatocarcinoma therapy.

FRONTIERS IN BIOSCIENCE-LANDMARK (2022)

添加到收藏夹

Article Cell Biology

CircMRE11A_013 binds to UBXN1 and integrates ATM activation enhancing lens epithelial cells senescence in age-related cataract

Junliang Liu et al.

Aging-US (2021)

添加到收藏夹

Article Chemistry, Medicinal

Evaluation of Gallic Acid-Coated Gold Nanoparticles as an Anti-Aging Ingredient

Yun-Zhen Wu et al.

Summary: The study demonstrated that GA-AuNPs have a superior ability to inhibit high-glucose-mediated MMP-1-elicited ECM degradation by reducing ROS production. These nanoparticles were found to block the phosphorylation of c-Jun, c-Fos, ATF-2, and NF kappa B through p38 MAPK/ERK signaling pathway, leading to the down-regulation of MMP-1 gene and protein expression under high glucose conditions.

PHARMACEUTICALS (2021)

添加到收藏夹

Article Biophysics

A resveratrol-loaded nanostructured lipid carrier hydrogel to enhance the anti-UV irradiation and anti-oxidant efficacy

Liu Miao et al.

Summary: Preparation of RES-loaded nanostructured lipid carrier gel (RES-NLC-gel) improved RES stability and accumulation in the epidermis. The gel effectively scavenged free radicals, protected skin cells from UV radiation, decreased expression of apoptotic proteins, and increased expression of survival proteins. Pretreatment with RES-NLC-gel reduced erythema, wrinkles, and scabs on mouse skin, decreased epidermal thickness, and increased antioxidant enzyme activities in skin tissue. RES-NLC-gel demonstrated significant anti-UV irradiation and antioxidant activity in vivo, showing great potential in skin protection.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Resveratrol delay the cataract formation against naphthalene-induced experimental cataract in the albino rats

Amrita Singh et al.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Resveratrol ameliorates rheumatoid arthritis via activation of SIRT1-Nrf2 signaling pathway

Gaoyuan Wang et al.

BIOFACTORS (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Resveratrol isomeric switching during bioreduction of gold nanoparticles: a gateway forcis-resveratrolArchita

Gupta et al.

NANOTECHNOLOGY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Direct Conjugation of Resveratrol on Hydrophilic Gold Nanoparticles: Structural and Cytotoxic Studies for Biomedical Applications

Iole Venditti et al.

NANOMATERIALS (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Development of resveratrol-conjugated gold nanoparticles: interrelationship of increased resveratrol corona on anti-tumor efficacy against breast, pancreatic and prostate cancers

Velaphi C. Thipe et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

添加到收藏夹

Article Medicine, General & Internal

Severe Abnormalities of Lens Epithelial Cells in Exfoliation Syndrome: A Transmission Electron Microscopy Study of Patients with Age-Related Cataract

Konstantina N. Sorkou et al.

MEDICINA-LITHUANIA (2019)

添加到收藏夹

Review Pharmacology & Pharmacy

Nanotechnology in regenerative ophthalmology

Fitsum Feleke Sahle et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

添加到收藏夹

Article Nanoscience & Nanotechnology

Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo

Duoduo Zhang et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2019)

添加到收藏夹

Article Cell Biology

Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury

Eun Nim Kim et al.

AGING-US (2018)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Senescent cells: an emerging target for diseases of ageing

Bennett G. Childs et al.

NATURE REVIEWS DRUG DISCOVERY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Unmasking Transcriptional Heterogeneity in Senescent Cells

Alejandra Hernandez-Segura et al.

CURRENT BIOLOGY (2017)

添加到收藏夹

Review Medicine, Research & Experimental

A focus on resveratrol and ocular problems, especially cataract: From chemistry to medical uses and clinical relevance

Ganesh Goutham et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

添加到收藏夹

Article Ophthalmology

SIRT1 Protects Human Lens Epithelial Cells Against Oxidative Stress by Inhibiting p53-Dependent Apoptosis

Tianyu Zheng et al.

CURRENT EYE RESEARCH (2016)

添加到收藏夹

Article Medicine, General & Internal

Effects of senescent lens epithelial cells on the severity of age-related cortical cataract in humans: A case-control study

Qiuli Fu et al.

MEDICINE (2016)

添加到收藏夹

Article Ophthalmology

Prevalence of Age-Related Cataract and Cataract Surgery in a Chinese Adult Population: The Taizhou Eye Study

Yating Tang et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2016)

添加到收藏夹

Review Ophthalmology

Nanotechnology for the Prevention and Treatment of Cataract

Sibel Cetinel et al.

ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY (2015)

添加到收藏夹

Review Geriatrics & Gerontology

Senescent cells: SASPected drivers of age-related pathologies

Yossi Ovadya et al.

BIOGERONTOLOGY (2014)

添加到收藏夹

Article Geriatrics & Gerontology

Resveratrol As Anti-Aging Therapy for Age-Related Bone Loss

Isabel F. Tresguerres et al.

REJUVENATION RESEARCH (2014)

添加到收藏夹

Article Ophthalmology

Aging and Age-Related Diseases of the Ocular Lens and Vitreous Body

J. Mark Petrash

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2013)

添加到收藏夹

Editorial Material Chemistry, Multidisciplinary

Nano/Microscale Motors: Biomedical Opportunities and Challenges

Joseph Wang et al.

ACS NANO (2012)

添加到收藏夹

Review Biochemical Research Methods

Ultrafast laser nanosurgery in microfluidics for genome-wide screenings

Adela Ben-Yakar et al.

CURRENT OPINION IN BIOTECHNOLOGY (2009)

添加到收藏夹

Article Multidisciplinary Sciences

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

KT Howitz et al.

NATURE (2003)

添加到收藏夹

Article Multidisciplinary Sciences

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

SJ Lin et al.

SCIENCE (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.