Sugammadex in Emergency Situations

Sugammadex may be required or used in multiple emergency situations. Moderate and high doses of this compound can be used inside and outside the operating room setting. In this communication, recent developments in the use of sugammadex for the immediate reversal of rocuronium-induced neuromuscular blockade were assessed. In emergency surgery and other clinical situations necessitating rapid sequence intubation, the tendency to use rocuronium followed by sugammadex instead of succinylcholine has been increasing. In other emergency situations such as anaphylactic shock caused by rocuronium or if intubation or ventilation is not possible, priority should be given to resuming ventilation maintaining hemodynamic stability, in accordance with the traditional guidelines. If necessary for the purpose of resuming ventilation, reversal of neuromuscular blockade should be done in a timely fashion.

Automated summary

Sugammadex is used in various emergency situations, including emergency surgery and rapid sequence intubation. The trend of using sugammadex after rocuronium instead of succinylcholine is increasing. In other emergency situations, such as anaphylactic shock caused by rocuronium or when intubation or ventilation is not possible, priority should be given to maintaining ventilation and hemodynamic stability, according to the traditional guidelines. Prompt reversal of neuromuscular blockade should be done if necessary for resuming ventilation.