相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Low-dose metformin targets the lysosomal AMPK pathway through PEN2
Teng Ma et al.
NATURE (2022)
Dose-dependent accumulation of glucose in the intestinal wall and lumen induced by metformin as revealed by 18F-labelled fluorodeoxyglucose positron emission tomography-MRI
Jun Ito et al.
DIABETES OBESITY & METABOLISM (2021)
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells
Ming Yang et al.
SCIENTIFIC REPORTS (2021)
Mechanism of glucose-lowering by metformin in type 2 diabetes: Role of bile acids
Daniel J. Sansome et al.
DIABETES OBESITY & METABOLISM (2020)
Long-term Effects of Metformin on Diabetes Prevention: Identification of Subgroups That Benefited Most in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study
David M. Nathan et al.
DIABETES CARE (2019)
Metformin acutely lowers blood glucose levels by inhibition of intestinal glucose transport
Olga Horakova et al.
SCIENTIFIC REPORTS (2019)
Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus
Marc Foretz et al.
NATURE REVIEWS ENDOCRINOLOGY (2019)
Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon-like peptide-1, and gastric emptying after oral glucose, in type 2 diabetes
Malcolm J. Borg et al.
DIABETES OBESITY & METABOLISM (2019)
Metformin Alters Upper Small Intestinal Microbiota that Impact a Glucose-SGLT1-Sensing Glucoregulatory Pathway
Paige V. Bauer et al.
CELL METABOLISM (2018)
Metformin: old friend, new ways of action-implication of the gut microbiome?
Julie Rodriguez et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2018)
High Accumulation of Metformin in Colonic Tissue of Subjects With Diabetes or the Metabolic Syndrome
Laura Paleari et al.
GASTROENTEROLOGY (2018)
Intestinal absorption of glucose in mice as determined by positron emission tomography
Monica Sala-Rabanal et al.
JOURNAL OF PHYSIOLOGY-LONDON (2018)
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo
Anila K. Madiraju et al.
NATURE MEDICINE (2018)
A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study
Hyewon Chung et al.
PLOS ONE (2018)
A reappraisal on metformin
Tugba Adak et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2018)
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase
Roger W. Hunter et al.
NATURE MEDICINE (2018)
Metformin as an Anticancer Agent
Ales Vancura et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk
Sara B. Seidelmann et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)
The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes
Andreas Bronden et al.
DIABETES OBESITY & METABOLISM (2018)
Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes
Emilie Bahne et al.
JCI INSIGHT (2018)
New insights into the anti-diabetic actions of metformin: from the liver to the gut
Tongzhi Wu et al.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY (2017)
Metformin - a new old drug
Marta Patrycja Wrobel et al.
ENDOKRYNOLOGIA POLSKA (2017)
Acute Effect of Metformin on Postprandial Hypertriglyceridemia through Delayed Gastric Emptying
Daisuke Sato et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Duodenal Sodium/Glucose Cotransporter 1 Expression Under Fasting Conditions Is Associated With Postload Hyperglycemia
Teresa Vanessa Fiorentino et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes: Results from a randomized clinical trial
Jukka P. Koffert et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2017)
Metformin: historical overview
Clifford J. Bailey
DIABETOLOGIA (2017)
The mechanisms of action of metformin
Graham Rena et al.
DIABETOLOGIA (2017)
The Primary Glucose-Lowering Effect of Metformin Resides in the Gut, Not the Circulation: Results From Short-term Pharmacokinetic and 12-Week Dose-Ranging Studies
John B. Buse et al.
DIABETES CARE (2016)
Bile Diversion in Roux-en-Y Gastric Bypass Modulates Sodium-Dependent Glucose Intestinal Uptake
Gregory Baud et al.
CELL METABOLISM (2016)
Metformin and the gastrointestinal tract
Laura J. McCreight et al.
DIABETOLOGIA (2016)
Selective sodium-dependent glucose transporter 1 inhibitors block glucose absorption and impair glucose-dependent insulinotropic peptide release
Robert L. Dobbins et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2015)
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
Kristoffer Forslund et al.
NATURE (2015)
The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH): Design of a pharmacogenetic Resource for Type 2 Diabetes
Geoffrey A. Walford et al.
PLOS ONE (2015)
Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
Hannah R. Bridges et al.
BIOCHEMICAL JOURNAL (2014)
Protective Effect of Metformin Against Walker 256 Tumor Growth is Not Dependent on Metabolism Improvement
Claudineia Conationi da Silva Franco et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2014)
Novel Gut-Based Pharmacology of Metformin in Patients with Type 2 Diabetes Mellitus
Antonella Napolitano et al.
PLOS ONE (2014)
Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose-Absorption and Glucose-Dependent Incretin Secretion
Valentin Gorboulev et al.
DIABETES (2012)
Diarrhea Caused By Carbohydrate Malabsorption
Heinz F. Hammer et al.
GASTROENTEROLOGY CLINICS OF NORTH AMERICA (2012)
Defining the Contribution of AMP-activated Protein Kinase (AMPK) and Protein Kinase C (PKC) in Regulation of Glucose Uptake by Metformin in Skeletal Muscle Cells
Sophie Turban et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Metformin primarily decreases plasma glucose not by gluconeogenesis suppression but by activating glucose utilization in a non-obese type 2 diabetes Goto-Kakizaki rats
Taishi Yoshida et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Protein Kinase-A Affects Sorting and Conformation of the Sodium-Dependent Glucose Co-Transporter SGLT1
Supriya Subramanian et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
Metformin and the intestine
C. J. Bailey et al.
DIABETOLOGIA (2008)
Dose translation from animal to human studies revisited
Shannon Reagan-Shaw et al.
FASEB JOURNAL (2008)
High and typical F-18-FDG bowel uptake in patients treated with metformin
Eric Gontier et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2008)
Inhibitory effect of metformin on intestinal glucose absorption in the perfused rat intestine
T Ikeda et al.
BIOCHEMICAL PHARMACOLOGY (2000)
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
MY El-Mir et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)